DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC101883531

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021333841.1	Gene:	LOC101883531 / 101883531	-ID:	-	Length:	398	Species:	Danio rerio

Alignment Length:	441	Identity:	97/441 - (21%)
Similarity:	159/441 - (36%)	Gaps:	119/441 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKLLIIGQL--------WLSIGLISGDDSLDTREGVDLVLKCRFT-------------------- 40
            |.||||.::        :.|:.:.:..||       .:::.|.||
Zfish    12 IFLLIINRVSCADWGVNYSSLHICALKDS-------SVIMSCTFTYPTGHQIMKVFWNKDLVIHG 69

  Fly    41 -EHYDSTDFTFYWARWTCCPTLFENVAIGDVQLNSNYRLDFRPSRGIYDLQIKNTSYNRDNGRFE 104
             ||.|.::...|..|..         .:||.|.|...||              :....:|..::.
Zfish    70 EEHADLSEDPEYSPRLQ---------YLGDKQQNCTVRL--------------SHVTKKDEHKYY 111

  Fly   105 CRIKAKGTGADVHQEFY--------NLTVLTAPHPPMVTPGNLAVATEEKPLELTCSSIGGSPD- 160
            ||..     .:|.:|.:        ::|.|....|..||.|:        .:.|||:|.....|
Zfish   112 CRFT-----TNVTKERWIGTPGVRLSVTDLQLESPERVTEGD--------SVRLTCNSSCELTDT 163

  Fly   161 PMITWYREGSTVPLQSYALKGGSKNHYTNAT----LQIVPRRADDGAKYKCVVWNRAMPEGHMLE 221
            |...|||...|:               |..|    |.:.|.|.:|..:|:|.|      :||.|.
Zfish   164 PTFIWYRNSHTL---------------TEGTIGDKLILNPVRREDAGRYRCAV------DGHTLT 207

  Fly   222 T-SVTLNVNYYP-RVEVGPQNPLKVERDHVAKLDCRVDAKPMVSNVRWSRNGQYVSATPTHTIYR 284
            : .|.|||.|.| .:.|.......:.......|:|..|:.| .:.:.|.:..::|.:.....|.:
Zfish   208 SPEVYLNVTYPPNNISVSISGSAVIMSGDSVTLNCSSDSNP-PAEIHWYKGTKFVGSGRIFNISK 271

  Fly   285 VNRHHAGKYTCSADNGLGKTGEKDIVLDVLYPPIVFIESKTHEA--EEGETVLIRCNVTANPSPI 347
            ::...:|:|.|...|.........:.|:|.|||.....|....|  ..|::|.:.|...:||..:
Zfish   272 ISSDDSGEYKCKTRNDHKVKYSDPVTLNVQYPPRNVSVSINGSAVIMSGDSVSLMCISDSNPPAL 336

  Fly   348 NVEWLKEGAPDFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSSKRVEGV 398
            :..|.||.......:|:     |..|..:|.:.|.:.|   |..::|.:.|
Zfish   337 SFSWFKENQSSAVGSGQ-----SFSAVQSGRFYCEAHN---PHGAQRSDAV 379

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845	20/125 (16%)
		IG_like	141..228	CDD:214653	24/92 (26%)
		Ig	147..228	CDD:299845	24/86 (28%)
		I-set	232..313	CDD:254352	14/81 (17%)
		IGc2	250..302	CDD:197706	11/51 (22%)
		IG_like	323..385	CDD:214653	15/63 (24%)
		IGc2	330..385	CDD:197706	13/54 (24%)
		Ig_2	416..501	CDD:290606
		IG_like	418..501	CDD:214653
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC101883531	XP_021333841.1	Ig	41..134	CDD:325142	19/120 (16%)
		Ig_3	140..199	CDD:316449	21/81 (26%)
		Ig	<184..216	CDD:325142	13/37 (35%)
		Ig_2	229..300	CDD:316418	12/71 (17%)
		Ig_2	314..383	CDD:316418	18/74 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010