DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fred and LOC100536927

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021333846.1	Gene:	LOC100536927 / 100536927	-ID:	-	Length:	376	Species:	Danio rerio

Alignment Length:	331	Identity:	81/331 - (24%)
Similarity:	125/331 - (37%)	Gaps:	87/331 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 PLQSYALKGGSKNHYTNATLQIVPRRADDGAKYKCVVWNRAMPEGHMLETSVTLNVNYYPRVE-V 236
            ||...|||..|       .:.....:...|.:.:.|.||:.:.:.......::::..|..|:: :
Zfish    93 PLHICALKDSS-------VIMSCTYKYPTGHQIRKVFWNKNLAKHREELADLSVDPEYSQRLQYL 150

  Fly   237 GP--QNPLKVERDHVAKLDCRVDAKPMVSNVRWSRNGQYVSATPTHTIYRVNRHHAGKYTCSADN 299
            |.  || ..|...||.|.|               .:..|...|...|        .||
Zfish   151 GDKRQN-CTVRLSHVTKKD---------------EHKYYFRFTTDKT--------RGK------- 184

  Fly   300 GLGKTGEKDIVLDVLYPPIVFIESKTHEAEEGETVLI----RCNVTANPSPI---NVEWLKEGAP 357
            |.|.||.:..|.|:.      :|| .....||::|.:    .||:|..|:.|   |.|.|.||.
Zfish   185 GTGNTGVRLSVTDLQ------LES-PERVTEGDSVRLTCRSSCNLTDTPTFIWYRNSERLTEGT- 241

  Fly   358 DFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSSKRVEGVGNSTVALLVRHRPGQAYIT-PNKP 421
                .|:.|.|..||.|..|.|.|            .|:|:.:..|.|.|.:.|....:: ....
Zfish   242 ----IGDKLILNPVRREDLGRYRC------------AVDGLTSPEVYLNVTYPPKSVSVSISGSA 290

  Fly   422 VVHVGNGVTLTCS--ANPPGWPVPQYRWFRDMDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCH 484
            |:..|:.|||:||  :|||.    |..|::.::        .:..|..::|.:......|:|.|.
Zfish   291 VIMSGDSVTLSCSSDSNPPA----QIFWYKGIE--------YVEYGRIFNISRISSDDSGEYKCR 343

  Fly   485 AVNELG 490
            |.:|.|
Zfish   344 AYSESG 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653	10/54 (19%)
		Ig	147..228	CDD:299845	10/54 (19%)
		I-set	232..313	CDD:254352	19/83 (23%)
		IGc2	250..302	CDD:197706	8/51 (16%)
		IG_like	323..385	CDD:214653	23/68 (34%)
		IGc2	330..385	CDD:197706	22/61 (36%)
		Ig_2	416..501	CDD:290606	20/78 (26%)
		IG_like	418..501	CDD:214653	20/75 (27%)
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC100536927	XP_021333846.1	Ig	103..196	CDD:325142	24/130 (18%)
		Ig_3	202..261	CDD:316449	22/64 (34%)
		Ig_2	289..360	CDD:316418	20/73 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010