Protein Alignment fred and si:ch211-180a12.2

DIOPT Version :9

• Sequence 1: NP_608812.3
• Gene: fred / 33613
• FlyBaseID: FBgn0051774
• Length: 1447
• Species: Drosophila melanogaster
• Sequence 2: XP_001920945.3
• Gene: si:ch211-180a12.2 / 100150385
• ZFINID: ZDB-GENE-121214-236
• Length: 903
• Species: Danio rerio
• Alignment Length: 980
• Identity: 193/980 - (19%)
• Similarity: 324/980 - (33%)
• Gaps: 275/980 - (28%)

  Fly     4 IKLLIIGQLWLSIGLISGDDSLD--TREGVDLVLKCRFTEHYDSTDFTFYWARWTCCPTLFENVA 66
            :|..::..||| :|||....|:|  ...|...||.|.|                 ..|.|.:|..
Zfish     1 MKFKVLSYLWL-LGLIKAGSSVDVSVSPGSSTVLNCSF-----------------ALPALVDNSL 47

  Fly    67 I-------GDVQLNSNY-RLDF------RPSRGIYDLQIKNTSYNRDNGRFECRIKAKGTGADVH 117
            :       |.:..:.|: :..|      .||   :.|.:.|.:.:: .|.:|||:....|  |..
Zfish    48 LNITWSSGGSIIASKNHTQAGFFLNSTAFPS---FPLTVFNATPHQ-QGVYECRVSYNDT--DYA 106

  Fly   118 QEFYNLTVLTAPHPPMVTPGNLAVATEEKPLELTCSSIGGSPDPMITWYREGSTV----PLQSYA 178
            .| ..||:|..|...:::|.  ||...:..:|....|. ..|..|.||.|.|:.:    .||...
Zfish   107 TE-VTLTILAPPVVSIISPE--AVLKRKSVVECWARSF-SPPQIMFTWTRGGNKIQEPQKLQVNR 167

  Fly   179 LKGGSKNHYTNATLQIVPRRADDGAKYKCVVWNRAMPEGHMLETSVTLNVNYYPRVEVGPQNPLK 243
            .:.|.  :...:.|..:|:.::....:.|.|.:.|:.:..:.|        :.|.:.|.|:..|.
Zfish   168 TEDGL--YDAVSFLTFIPQISNQNISFGCEVQHSALVKPVLEE--------FTPHITVLPKVTLS 222

  Fly   244 V--ERDHVAKLDCRVDAKPMVSN---VRWSRNGQYVSATPT--------------HTIYRVNRHH 289
            |  ...|.:.:....|......|   |.|..||:.:|..|.              ||:.|..|..
Zfish   223 VVPSSSHSSSVTLSCDISGFYPNNISVLWIHNGKKLSELPLSIQNEDGTYRRHQYHTLTREERSR 287

  Fly   290 AGKYTCSA-----------------------DNGLGKTGEKDIVLDVLYPPIVFIESKTHEAEEG 331
            .|:..|.|                       :.||.|:.:..:.:.::...:||:.......:..
Zfish   288 GGEVQCVALQPSGQEPANGTIDLSTVDLRVQNPGLNKSAKASVAMMIISLTLVFLLCFGFSWKRR 352

  Fly   332 ETVLIRCNVTANPSPINVEWLKEGAPDFRYTGELLTLGSVRAEHA-GNYICRSVNIMQPFSSKRV 395
            :..|...|::|...|..|...|:|.......|.|       ||.. ..:....:.|......::.
Zfish   353 DEKLKSLNISAIVLPPRVVVGKKGRVTISVEGRL-------AERVQTTWFLNDIPIKDTSHKEKK 410

  Fly   396 EGVGNSTVALLVRHRPGQAYITPNKPVVHVGNGVTLTCSANP--PGWPVPQYRWFRDMD-GDIGN 457
            .|...|.           :|.:.|       :.|::....||  |......|:....|. ....|
Zfish   411 YGAFRSA-----------SYTSRN-------SSVSVLSEKNPLLPSSASGYYKLHTQMPLRSSSN 457

  Fly   458 TQKILAQGPQYSIPK--AHLGSEGKYHCHAVNELGIGKIA--------TIILEVHQPPQFLAKLQ 512
            :.|.|.....: ||.  .|.||  .:.|. |:..|..||.        ||:    .||: ::::|
Zfish   458 SSKQLFSSVTF-IPSLAVHKGS--VFKCQ-VSYKGKDKIVAERVSEKFTIL----APPE-VSEIQ 513

  Fly   513 QHMTRRVGDVDYAVTCSAKGKP-TPQI---RWIKDGTEILPTRKMFDIRTTPTDAGGGVVAVQSI 573
            .......|.|   ||.:|.... .|.|   ||..:|.|:.|                  |::...
Zfish   514 FSEPNEEGGV---VTMTAHASHFHPDIITFRWFCEGGELSP------------------VSIPQA 557

  Fly   574 LRFRGKARPNGNQLLPNDRGLYTC-----LYENDVNSANSSMHLRIEH----EPIV------IHQ 623
            |     |.|.     |:..|.::.     |.:.::....:.:.:.|.|    :||.      |.|
Zfish   558 L-----AAPR-----PDAEGFFSAMSQCRLPKAELERGETRVWVTIHHTALKQPITRQTRGFIKQ 612

  Fly   624 YN-------KVAYDLRESAEVVCRVQAYPKPEF--QWQY--GNNPSPLTMSSDGHYEISTRMENN 677
            .:       .||..|.....:.|.:..:..||.  :|.:  ||.   :....|...||.   :..
Zfish   613 PSISEILSCPVASVLEGRLTLACEITGFYPPEISVKWLHSKGNE---IEDGDDSEEEIK---DGA 671

  Fly   678 DVYTSILRIAHL-----------QHSDYGEYICRA-----VNPLDSIRAPIRLQPKGSPEKPTNL 726
            :|:..:..:...           :.:..|:.|||.     :.|:|.:   .|.....:|..|.:|
Zfish   672 EVWGPLQTLPRTFRAKALLKDVNEMTRGGQIICRVSHCCLLKPVDRV---WRNTHTVAPSIPPSL 733

  Fly   727 KILEVGHNYAVLNWTPGFNGGFMSTKYLVSYRRVATPREQTLSDCSGNGYIPSYQISSSSSNSNH 791
            .:          :|:....|.|  :..|...|    |..:.|. .:|...:...|.......:|.
Zfish   734 SV----------HWSSDGVGIF--SIVLCGGR----PSAEVLW-AAGGSTLSRLQSKERERENNE 781

  Fly   792 EWIEFNCFKENPCKLAPLDQHQSYMFKVYALNSKGTSGYSNEILATTKVSKIPPPLHVSYDPNSH 856
            ..:|.    ::.|.|.                 :.|....:|....|...||.||   |.|.|:.
Zfish   782 GKLEL----KSVCALV-----------------RSTGRKDSESRRGTHARKIRPP---SVDFNTD 822

  Fly   857 VLGIN 861
            ...:|
Zfish   823 YEKVN 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845	24/110 (22%)
		IG_like	141..228	CDD:214653	18/90 (20%)
		Ig	147..228	CDD:299845	17/84 (20%)
		I-set	232..313	CDD:254352	24/122 (20%)
		IGc2	250..302	CDD:197706	16/91 (18%)
		IG_like	323..385	CDD:214653	11/62 (18%)
		IGc2	330..385	CDD:197706	11/55 (20%)
		Ig_2	416..501	CDD:290606	22/97 (23%)
		IG_like	418..501	CDD:214653	22/95 (23%)
		I-set	505..612	CDD:254352	21/115 (18%)
		Ig	526..611	CDD:143165	17/93 (18%)
		IG_like	633..715	CDD:214653	17/101 (17%)
		Ig	635..713	CDD:143165	16/97 (16%)
		FN3	720..838	CDD:238020	18/117 (15%)
si:ch211-180a12.2	XP_001920945.3	Ig	19..114	CDD:299845	26/118 (22%)
		IG_like	22..113	CDD:214653	24/114 (21%)
		C1-set	123..205	CDD:284964	19/86 (22%)
		IgC	237..309	CDD:143166	15/71 (21%)
		IgC	515..604	CDD:143166	23/119 (19%)
		IgC	609..720	CDD:143166	21/119 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900