DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC100006752

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021333405.1	Gene:	LOC100006752 / 100006752	-ID:	-	Length:	385	Species:	Danio rerio

Alignment Length:	273	Identity:	67/273 - (24%)
Similarity:	97/273 - (35%)	Gaps:	75/273 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 IGDVQLNSNYRLDFRPSRGIYDLQIKNTSYNRDNGRFECRIKAKGTGADVHQE--------FYNL 123
            :||.|.|...||              :....:|...:..||.     .||.:|        ..::
Zfish    87 LGDKQQNCTVRL--------------SHVTEKDKHEYYFRII-----TDVREERWIGKPGVILSV 132

  Fly   124 TVLTAPHPPMVTPGNLAVATEEKPLELTC-SSIGGSPDPMITWYREGSTVPLQSYALKGGSKNHY 187
            |.|....|..||.|:        .:.||| ||...:..|...|||...|:..:..    |.|
Zfish   133 TDLQLESPERVTEGD--------SVHLTCRSSCNLTDTPTFIWYRNSHTLTKEMI----GDK--- 182

  Fly   188 TNATLQIVPRRADDGAKYKCVVWNRAMPEGHMLET-SVTLNVNYYPR-VEVGPQNPLKVERDHVA 250
                |.:.|.|.:|..:|:|.|      .||.|.: .|.|||.|.|| |.|......::..:.|:
Zfish   183 ----LILDPVRREDAGRYRCAV------HGHTLTSPEVYLNVTYPPRNVSVSTNYSGQLWLNSVS 237

  Fly   251 KLDCRVDAKPMVSNVRWSR--------NGQYVSATPTHTIYRVNRHHAGKYTCSADNGLGKTGEK 307
             |.|..|:.|...:..|..        :||..||.           .:|::.|.|.|..|.....
Zfish   238 -LMCISDSNPPALSFSWFEENQSSAVGSGQSFSAV-----------QSGRFYCEAHNPHGAQRSD 290

  Fly   308 DIVLDVLYPPIVF 320
            .:.:.|..|..:|
Zfish   291 AVTVTVKGPRELF 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845	13/66 (20%)
		IG_like	141..228	CDD:214653	24/88 (27%)
		Ig	147..228	CDD:299845	24/82 (29%)
		I-set	232..313	CDD:254352	19/89 (21%)
		IGc2	250..302	CDD:197706	13/59 (22%)
		IG_like	323..385	CDD:214653
		IGc2	330..385	CDD:197706
		Ig_2	416..501	CDD:290606
		IG_like	418..501	CDD:214653
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC100006752	XP_021333405.1	Ig	41..133	CDD:325142	12/64 (19%)
		Ig_3	139..198	CDD:316449	21/77 (27%)
		Ig	<183..215	CDD:325142	13/37 (35%)
		Ig_2	235..296	CDD:316418	15/72 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010