Protein Alignment capu and Daam2

DIOPT Version :9

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_001008232.2
• Gene: Daam2 / 76441
• MGIID: 1923691
• Length: 1115
• Species: Mus musculus
• Alignment Length: 1189
• Identity: 250/1189 - (21%)
• Similarity: 423/1189 - (35%)
• Gaps: 341/1189 - (28%)

  Fly   338 PLANGELFNVSKAKKVELQNLSSRFTAAVTQTPP----------GVTSSTPNESGVTGPAGPLGA 392
            |:.|.|..||..|:.|:..:|:.:...||...||          ......||:...:.|...:..
Mouse    41 PIPNPEELNVRFAELVDELDLTDKNREAVFALPPEKKWQIYCSKRKEQEDPNKLATSWPEYYIDR 105

  Fly   393 TTSSPSLETQSTVIISFKSSQTPVQSQTNSAASENVED-DTAPLPLPPPPPGFGT------PTTP 450
            ..:..:::.    :...:..:|..::|.       ||| .||   |...|..|.|      ..|.
Mouse   106 INAMAAMQN----LYETEDEETDKRNQV-------VEDLKTA---LRTQPMRFVTRFIDLEGLTC 156

  Fly   451 LLSSNVLKKVASFTVEK----SSAG------NNSSNPPNLCPTSDETTLLATPCSSSLTVATLPP 505
            ||  |.|:.:...|.|.    |..|      |||....::....:..:::|    .||.......
Mouse   157 LL--NFLRGMDHTTCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISIIA----QSLRTENSKT 215

  Fly   506 EIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAY--EKFEGQMLIKWLISTM-----QSNPKSSSG 563
            ::||....|.|....|..:  ..:...|.:.||  |:...|.|:..|..::     :.|.|::..
Mouse   216 KVAVLEILGAVCLVPGGHK--KVLQAMLHYQAYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIM 278

  Fly   564 DANQELFNTLA----LQFCNNLKY----VGV------LKQISNEHLDCGFSPYEM---------- 604
            .....:.|..|    |:|..:|:|    :|:      |:|..|..||.....:||
Mouse   279 SFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELA 343

  Fly   605 --YQWTH--TEQPTTSLPLTPGKLDKVAAWPFSSTPSGIRALESASLASLGAGGVAGSLATIATA 665
              :...|  |:..:....|...||....|:|                          .|.::.
Mouse   344 RRFDMVHIDTKSASQMFELIHKKLKHTEAYP--------------------------CLLSVL-- 380

  Fly   666 STASSDNQKTLQQILKK------------RLLNCTTLAEVHAVVNELLSSVDEPPRRP-----SK 713
                   ...||...|:            |:|....|.:...|         :|...|     .|
Mouse   381 -------HHCLQMPYKRNGGYFQQWQLLDRILQQIVLQDERGV---------DPDLAPLENFNVK 429

  Fly   714 RCVNLTELLNASEATVY-----EYNKTGAE---GCVKSFTDAETQT-ESEDCEGTCKCGQSSTKV 769
            ..||:  |:|.:|...:     ::.|...|   ...:...:.||:| |.|:...|....:.....
Mouse   430 NIVNM--LINENEVKQWRDQAEKFRKEHMELMSRLERKERECETKTLEKEEMMRTLNKMKDKLAR 492

  Fly   770 SDNESAKEDGEKPHAVAPPPPPPPPPLHAFVAPPPPPPPP------------PPPPPPLANYGAP 822
            ...|..:..|:....||........|    |:.||||..|            |||||||.....|
Mouse   493 ESQELRQARGQVAELVARHNESSTGP----VSSPPPPGGPLTLSSSRTTNDLPPPPPPLPFDSCP 553

  Fly   823 PPPPPP-PPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWFHRTNTM 886
            |||.|| |||   .||.||.||.....|.||...|.|:       :.|||              .
Mouse   554 PPPAPPLPPG---GPPIPPGAPPCFSSGPPPSHDPFSS-------NEAPL--------------R 594

  Fly   887 RKSAVNPPKPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPAT 951
            :|....|..|::...|.::                 :....||:
Mouse   595 KKRIPQPSHPLKSFNWVKL-----------------NEERVSGT--------------------- 621

  Fly   952 KEIWTEIEETPLDNI---DEFTELF---------------------------------------- 973
              :|.||:::.:..|   ::|.::|
Mouse   622 --VWNEIDDSQVFRILDLEDFEKMFSAYQRHQACMQEGPQRERGNVRDGGAASRPLPAVEASAHR 684

  Fly   974 ----SRQAIAPVSKPKEL--------KVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYH 1026
                ||..::.....|||        ..::.|.:.|:|..|::|..|:...|.:.:.||..||..
Mouse   685 TEKASRSMVSATGAKKELGSTEDIYITSRKVKELSVIDGRRAQNCIILLSKLKLSNDEIRQAILR 749

  Fly  1027 IDTSV-VSLEALQHM-------SNIQATEDELQRIKEAAGGDIPLDHPEQFLLDISLISMASERI 1083
            :|... ::.:.|:.:       |:|...|:....|:..|..|       :||.::|.|....:|:
Mouse   750 MDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARAD-------RFLYEMSRIDHYQQRL 807

  Fly  1084 SCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNL 1148
            ..:.|:.:|:|.:.....|:|.:...|::|..|:.||.:..::|.:||:||.|  |||.|.||.:
Mouse   808 QALFFKKKFQERLAEAKPKVEAILLASRELTLSQRLKQMLEVVLAIGNFMNKG--QRGGAYGFRV 870

  Fly  1149 DILGKLKDVKSK-ESHTTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPADVERAAQMDFEEVQQQ 1212
            ..|.|:.|.||. :.:.:|||:::...      |...|..:.:| .|...:..||:::..|::::
Mouse   871 ASLNKIADTKSSIDRNISLLHYLIMIL------EKHFPDILNMP-SELKHLSEAAKVNLAELEKE 928

  Fly  1213 IFDLNKKFLGCKRTTAKVLAASRPEIMEP---FKSKMEEFVEGADKSMAKLHQSLDECRDLFLET 1274
            :..|.:..    |.....|...|.:..:|   |...|.:|:..:..|.::|...|:|.||.|.:.
Mouse   929 VSILRRGL----RAVEVELEYQRHQARDPNDKFVPVMSDFITVSSFSFSELEDQLNEARDKFAKA 989

  Fly  1275 MRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVS 1339
            :.  ||..:.     ::..||:||..:..|...|     .|....|..:.::.::.:..:|....
Mouse   990 LT--HFGEQE-----SKMQPDEFFGIFDTFLQAF-----LEARQDLEAMRRRKEEDERRARMEFM 1042

  Fly  1340 TKVEKSGRISLKERMLMRR 1358
            .|.::.     |||...:|
Mouse  1043 LKEQRE-----KERWQRQR 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	101/493 (20%)
Daam2	NP_001008232.2	Drf_GBD	43..228	CDD:283920	44/204 (22%)
		Drf_FH3	231..435	CDD:283917	44/251 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	510..605		39/122 (32%)
		FH2	595..1016	CDD:280362	100/487 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	655..697		2/41 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810