Protein Alignment capu and diaph2

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: XP_021336921.1
• Gene: diaph2 / 556029
• ZFINID: ZDB-GENE-090115-1
• Length: 1166
• Species: Danio rerio
• Alignment Length: 688
• Identity: 188/688 - (27%)
• Similarity: 298/688 - (43%)
• Gaps: 128/688 - (18%)

  Fly   702 SSVDEPPRRPSKRCVNLTELLNASEATVYEYNKTGAEGCVKSFTDAETQTESEDCEGTC---KCG 763
            :.|||..:|.::......|..:|.:....|..|  .|..:|:|   |:|..:...:.|.   |..
Zfish   478 AKVDESEQRAAEFSKKFDEEFSARQEAQAELQK--QEEKIKAF---ESQINTLQAQLTSERDKLK 537

  Fly   764 QSSTKVSDNESAKEDGEKPHAVAPPPPPPPPPLHAFVAPPPPPP---------PPPPPPPPL-AN 818
            ::...:|:..|....|.|.....||||||||   ..:|||||||         ||||||||. |:
Zfish   538 EAEKSISERNSKIAAGPKAAGAGPPPPPPPP---GGIAPPPPPPPPPPPIGGAPPPPPPPPFPAS 599

  Fly   819 YGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWFHRT 883
            .|  |||||||||.|..||||||     ||| |||||.|.::|....:.   ||          .
Zfish   600 LG--PPPPPPPPGCGPPPPPPPP-----GGG-PPPPPGMPSAPPPLVVQ---LP----------Y 643

  Fly   884 NTMRKSAVNPPKPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAP 948
            ....|....|...|:.:.|::||        |..:|      ||.
Zfish   644 GLAPKKTYKPDSIMKRVNWSKIV--------PQEMA------ENC-------------------- 674

  Fly   949 PATKEIWTEIEETPLDNIDEFTEL-FSRQAIAPVSKPKE--------LKVKRAKSIKVLDPERSR 1004
                 .|.:::|...:|.|.|:|| .|..:.:.|.|..|        .| |:||.:::||.:.::
Zfish   675 -----FWLKVKEERFENTDMFSELSLSFSSKSRVKKDVEETDDRMTQFK-KKAKELRILDAKTAQ 733

  Fly  1005 NVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQATEDELQRIKEAAGGDIPLDHPEQF 1069
            |:.|...|..:|..||...:..:|...:|...:|::......:.||..:.|.......|...|||
Zfish   734 NLSIFLGSFRLPYEEIRDIVLQVDEERLSEALIQNLIKNLPEQKELSNLAELKNEYEELCESEQF 798

  Fly  1070 LLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMN 1134
            .:.:|.:.|...|::.|:|:..|||.|..:...:..|:...:::.:||...::..::|.:|||||
Zfish   799 GIVMSSVKMLRPRLNGILFKLTFEEQVNNIRPDIMNVTFACEEVKKSEGFHMLLEMVLLVGNYMN 863

  Fly  1135 GGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPADVE 1199
            .|:| ..|..|||:..|.||:|.||.:.:||||||:.      .:.|..:|..::.| .|...||
Zfish   864 SGSR-NAQTFGFNISFLCKLRDTKSTDQNTTLLHFLA------EKCEEKYPEMLKFP-DELEHVE 920

  Fly  1200 RAAQM-------DFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEPFKSKMEEFVEGADKSM 1257
            .|:::       ..:.:::.|..|........:|..|         .:.|..||..|.:.:.:..
Zfish   921 SASKVAAQTLKASLDIMERHIQRLENDIQNFPKTDDK---------QDKFVEKMSGFSKHSREQY 976

  Fly  1258 AKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNE 1322
            .||.......:.|:.....::.|.|...::       :.||....||.|.|.|..::....  .|
Zfish   977 EKLSTMHKNMQKLYENLGSYFAFDPHTVSI-------EDFFGDLANFRNLFMDAVRENHKK--RE 1032

  Fly  1323 LMKKSKQAQIESRRNVSTKVEKSGRISLKERMLMRRSK 1360
            :.:|.|:|:|...:....|:|:    ..|::.|:..:|
Zfish  1033 MEEKIKRAKIAKEKAEREKIER----QQKKKQLIDMNK 1066

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	106/442 (24%)
diaph2	XP_021336921.1	Drf_GBD	86..276	CDD:461886
		Drf_FH3	284..470	CDD:461885
		EnvC	477..>545	CDD:443969	15/71 (21%)
		FH2	647..1020	CDD:396655	104/436 (24%)