Protein Alignment capu and Diaph2

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: XP_006528644.1
• Gene: Diaph2 / 54004
• MGIID: 1858500
• Length: 1109
• Species: Mus musculus
• Alignment Length: 721
• Identity: 182/721 - (25%)
• Similarity: 313/721 - (43%)
• Gaps: 155/721 - (21%)

  Fly   674 KTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKRCVNLTELLNA--SEATVYEYNKTG 736
            |.:::.:.:.:|:|              |.:|...:...:...:.|.||:|  ::|.| |.|:..
Mouse   457 KIIEECVSQIVLHC--------------SGMDPDFKYRQRIDFDFTHLLDACVNKAKV-EENEQK 506

  Fly   737 AEGCVKSFTDAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGE-KPHAVAPPPPPPPPPLHAFV 800
            |....|.|.  |..|..::.:...:......|..:.|..:..|: .|.|:..||||||.|   ..
Mouse   507 AMEFSKKFD--EEFTARQEAQAELQKRDEKIKELETEIQQLRGQGVPSAIPGPPPPPPLP---GA 566

  Fly   801 APPPPPPPPPPPPPPLANYGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTT 865
            .|.|||||||||||||.  |..||||||.||....|||||| |:.|..  ||||||....|..:
Mouse   567 GPCPPPPPPPPPPPPLP--GVVPPPPPPLPGMPGIPPPPPP-PLSGVP--PPPPPPGGVFPLLS- 625

  Fly   866 ISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGS 930
             .|..||          ....:|....|..||:.:.|::|      .|:        :.:||.
Mouse   626 -GPIELP----------YGMKQKKLYKPDIPMKRINWSKI------EPK--------ELSENC-- 663

  Fly   931 SPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNIDEFTELFSRQAIAPVSKPKELK------- 988
                                   :|.:::|...:|.|.|.:|       .::.|.::|
Mouse   664 -----------------------VWLKLKEEKYENADLFAKL-------ALTFPSQMKGQRNTEA 698

  Fly   989 ---------VKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSLEALQHMSNIQ 1044
                     .|:.|.:::||.:.::|:.|...|..:|..||::.|..::..::|...:|::....
Mouse   699 AEENRSGPPKKKVKELRILDTKTAQNLSIFLGSYRMPYEEIKNIILEVNEEMLSEALIQNLVKYL 763

  Fly  1045 ATEDELQRIKEAAGGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQL 1109
            ..::.|:.:.:.......|..||||.:.:|.:.|...|::.|:|:..|||.|..:...:..|:..
Mouse   764 PDQNALRELAQLKSEYDDLCEPEQFGVVMSTVKMLRPRLTSILFKLTFEEHVNNIKPSIIAVTLA 828

  Fly  1110 SQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKESHTTLLHFIVRTY 1174
            .::|.:||..|.:..:||.:|||||.|:| ..|:.||.::.|.|:||.||.:..:|||||:..
Mouse   829 CEELKKSESFKRLLELILLVGNYMNSGSR-NAQSLGFKINFLCKIKDTKSADQKSTLLHFLAE-- 890

  Fly  1175 IAQRRKEGVHPLEIRLPIPEPAD-VERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEI 1238
            |...:...:      |..|:..: ||.|.::..:.::..:..:.:..|..::.......|....
Mouse   891 ICDEKYRDI------LKFPDELEHVESAGKVSAQILKSNLVAMEQSILHLEKNIKNFPPAESHH- 948

  Fly  1239 MEPFKSKMEEFVEGA----DK------SMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCT 1293
             :.|..||..|.:.|    ||      :|.||::||.|          ::.|.|....:
Mouse   949 -DKFVEKMMSFTQNAREQYDKLSTMHSNMLKLYESLGE----------YFIFDPNTVNM------ 996

  Fly  1294 PDQFF----EYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTKVEKSGRISLKERM 1354
             ::||    .:.|.|....|:..|::      |:.:||::|::...:....|:|:    ..|::.
Mouse   997 -EEFFGDLNTFRTLFLEALKENHKRK------EMEEKSRRAKLAKEKAEQEKLER----QKKKKQ 1050

  Fly  1355 LMRRSK 1360
            |:..:|
Mouse  1051 LIDINK 1056

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	102/457 (22%)
Diaph2	XP_006528644.1	Drf_GBD	102..294	CDD:461886
		Drf_FH3	302..490	CDD:461885	6/46 (13%)
		FH2	636..1010	CDD:396655	99/447 (22%)