Protein Alignment capu and fmnl3

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_001333083.1
• Gene: fmnl3 / 407694
• ZFINID: ZDB-GENE-030131-1571
• Length: 1047
• Species: Danio rerio
• Alignment Length: 921
• Identity: 203/921 - (22%)
• Similarity: 332/921 - (36%)
• Gaps: 284/921 - (30%)

  Fly   511 AAAGGVAGGAGSRRGSSYVPEKLSFAAYEKFEGQMLIKWLISTMQSNPKSSSGDANQELFNTLAL 575
            ||...|.||           .::..:|::.|:.....|.....:....:|..|:.:   |....:
Zfish   264 AAVCLVRGG-----------HEIILSAFDNFKEVCKEKHRFEKLMEYFRSEDGNID---FMVACM 314

  Fly   576 QFCNNLKYVGVLKQISNEHLDCGFSPYEMYQWT------------HTEQPTTSLPLTPGKLDKVA 628
            ||.|.:.:       |.|  |..|..:..|::|            |||....|:.: ...||.|
Zfish   315 QFINIVVH-------SVE--DMNFRVHLQYEFTKLGLDDFLEKSKHTESDKLSVQI-QAYLDNV- 368

  Fly   629 AWPFSSTPSGIRALESASLASLGAGGVAGSLATIATASTASSDNQKTLQQILKKRL-LNCTTLAE 692
                                 ...||:.....|...|.....:.::.|..:.:|.| :...|:.:
Zfish   369 ---------------------FDVGGLLEDAETKNVALEKVEELEEHLSHVTEKLLDVENETMTK 412

  Fly   693 VHAVVNEL------LSSVDEPPRRPSKRCVNLTELLNASEATVYEYNKTGAEGCVKSFTDAETQT 751
            |..:..:|      |:.:.|.....|.:...|..::...:|....:|            :.|.|.
Zfish   413 VADLEKQLLHKDKELAVIKETYESASTQVHTLRRMIQEKDAAFQRHN------------NIEKQL 465

  Fly   752 ESEDCEGTCKCGQ----------------SSTKVSDNES-----------AKEDGEKPHAVAPPP 789
            ...:.:||.:..:                :.|.::|..|           .........||||||
Zfish   466 LELEQQGTIRLRKQPDGDIAIETLGAGAVAGTPLTDLRSLTVGMSTIGGLGGTSAVPVEAVAPPP 530

  Fly   790 PPPPPPLHAFVAPPPPPPPPPPPPPPLANYGAPPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPP 854
            ||||        |||||||.||.|..:.:...|||||||.||       |.|:.|...|
Zfish   531 PPPP--------PPPPPPPAPPLPSEVESIPIPPPPPPPLPG-------PSPSVILSVG------ 574

  Fly   855 PPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMR-----PLY-WTRIVTSAPPAP 913
                                             .||:...||::     |:: ||.:
Zfish   575 ---------------------------------LSAIRIKKPIKTKFRLPVFNWTAL-------- 598

  Fly   914 RPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEE----TPLDNIDEFTELFS 974
                                :|...||.            ::.||::    ..|| :::|.|||.
Zfish   599 --------------------KPNQINGT------------VFNEIDDDRVLEELD-LEKFEELFK 630

  Fly   975 RQAIAPV-----SKPKELKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTSVVSL 1034
            .:|..||     ||.| :..|....:::||..||:|:.|..|..:..:.||..||...|...:.:
Zfish   631 TKAQGPVVDLSCSKSK-VSQKVINKVQLLDANRSKNLAITLRKANKTTEEICKAIQTFDLKALPV 694

  Fly  1035 EALQHMSNIQATEDELQRIKEAAGGDIPLD---HPEQFLLDISLISMASERISCIVFQAEFEESV 1096
            :.::.:.....||.|.:.:::......|||   ..::|:|..|.|...::|:|.|.|...|.::|
Zfish   695 DFVECLMRFLPTEAESKLLRQYERERRPLDQLAEEDRFMLLFSKIERLTQRMSIITFVGNFNDNV 759

  Fly  1097 TLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSKE 1161
            .:|..:|..:...|..:..|..||.:..|||.||||||  :.:||...||.|..|..|.|.||.:
Zfish   760 NMLTPQLNAIIAASASVKSSPKLKKILEIILALGNYMN--SSKRGSVYGFKLQSLDLLLDTKSTD 822

  Fly  1162 SHTTLLHFIVRTYIAQRRKEGVHPLEIRLPIPEPAD-------VERAAQMDFEEVQQQIFDLNKK 1219
            ...||||:|.              |.::...||.|:       |::||.:..|.|.     |:.|
Zfish   823 RKMTLLHYIA--------------LVVKEKYPELANFYNELHFVDKAAAVSLENVL-----LDVK 868

  Fly  1220 FLGCKRTTAKVLAASRPEIMEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKA 1284
            .||      |.:...|.|......:.::.|.:.:|..:.||.:......:.|...:.::..|||.
Zfish   869 ELG------KGMDLVRRECSLHDHAVLKGFAQTSDTQLDKLAKDAKTAEEAFNNVVLYFGESPKT 927

  Fly  1285 CTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQAQIESRRNVSTKVEKSGRIS 1349
                   ..|..||..:..|...:|:..::      ||..||.::|
Zfish   928 -------TPPSVFFPVFVRFIRAYKEAVEE------NEQRKKQEEA------------------- 960

  Fly  1350 LKERMLMRRSK 1360
            ::|::|.:.:|
Zfish   961 MREKLLAQEAK 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	112/451 (25%)
fmnl3	NP_001333083.1	Drf_GBD	23..268	CDD:461886	2/3 (67%)
		Drf_FH3	271..462	CDD:461885	40/248 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	520..561		25/48 (52%)
		FH2	580..945	CDD:396655	109/440 (25%)
		CwlO1	<941..>999	CDD:443091	9/56 (16%)