Protein Alignment capu and Daam1

DIOPT Version :9

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: XP_038968188.1
• Gene: Daam1 / 314212
• RGDID: 1305119
• Length: 1078
• Species: Rattus norvegicus
• Alignment Length: 1190
• Identity: 273/1190 - (22%)
• Similarity: 445/1190 - (37%)
• Gaps: 328/1190 - (27%)

  Fly   327 TMEPCAAGSGSPLANGELFNVSKAKKVELQNLSSRFTAAVTQTPPG-----VTSSTPNESGVTGP 386
            ||||..     |:...|..:|..::.|:..:|:.:...|:...|..     ..|...::....|
  Rat    40 TMEPAL-----PMPPVEELDVMFSELVDELDLTDKHREAMFALPAEKKWQIYCSKKKDQEENKG- 98

  Fly   387 AGPLGATTSSPSLETQSTVIISFKSSQTPVQSQTNSAASENVED-DTAPLPLPPPPPGFGTPTTP 450
                  .||.|.........::.:.|...::.:.....|:.:|. .||   |...|..|.|....
  Rat    99 ------ATSWPEFYIDQLNSMAARKSLLALEKEEEEERSKTIESLKTA---LRTKPMRFVTRFID 154

  Fly   451 L--LSS--NVLK----KVASFTVEKSSAG------NNSSNPPNLCPTSDETTLLATPCSSSLTVA 501
            |  ||.  |.||    :.:...:..|..|      |||....::...|:...::|    .||:..
  Rat   155 LDGLSCILNFLKTMDYETSESRIHTSLIGCIKALMNNSQGRAHVLAHSESINVIA----QSLSTE 215

  Fly   502 TLPPEIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAY--EKFEGQMLIKWL-ISTMQSNPKSSSG 563
            .:..::||....|.|....|..:  ..:...|.:..|  |:...|.||..| .||.:...:.|..
  Rat   216 NIKTKVAVLEILGAVCLVPGGHK--KVLQAMLHYQKYASERTRFQTLINDLDKSTGRYRDEVSLK 278

  Fly   564 DANQELFNTL--------ALQFCNNLKY----VGV------LKQISNEHLDCGFSPYEM------ 604
            .|.....|.:        :|.|..:|:|    :|:      |::..|..||.....:||
  Rat   279 TAIMSFINAVLSQGAGVESLDFRLHLRYEFLMLGIQPVIDKLREHENSTLDRHLDFFEMLRNEDE 343

  Fly   605 ------YQWTH--TEQPTTSLPLTPGKLDKVAAWP-FSSTPSGIRALESASLASLGAGGVAGSLA 660
                  ::..|  |:..|....||..:|....|:| |.|.                       |.
  Rat   344 LEFAKRFELVHIDTKSATQMFELTRRRLTHSEAYPHFMSI-----------------------LH 385

  Fly   661 TIATASTASSDN--------QKTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRR--PSKRC 715
            .........|.|        .:.:|||:               :.|:.....|..|..  ..|..
  Rat   386 HCLQMPYKRSGNTVQYWLLLDRIIQQIV---------------IQNDKGQDPDSTPLENFNIKNV 435

  Fly   716 VNLTELLNASEATVYEYNKTGAEGCVKSFTDAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGE 780
            |.:  |:|.:|...:   |..||...|...:.:.:.|.::.|...|..:....:......||..|
  Rat   436 VRM--LVNENEVKQW---KEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLE 495

  Fly   781 KP-----------------------HAVAPPPPPPPPPLHAFVAPPPPPPPP------PPPPPPL 816
            |.                       .||....|..|.|    .||..|.||.      |||||||
  Rat   496 KETTEHKQVKQQVADLTAQLHELNRRAVCASVPGGPSP----GAPGGPFPPSGLGSLLPPPPPPL 556

  Fly   817 ANYGA-PPPPPPPPPGSGSAPPPPPPAPIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWF 880
            .:.|| ||||||.|||.    |||||.|...||.:|||..|:|.:..|..|     |.|
  Rat   557 LSGGALPPPPPPLPPGG----PPPPPGPPPLGGILPPPGAPVSLTLKKKNI-----PQP------ 606

  Fly   881 HRTNTMRKSAVNPPKPMRPLYWTRIVTSAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPP 945
              ||.::.           ..|:::          |.  |..:.|
  Rat   607 --TNALKS-----------FNWSKL----------PE--NKLEGT-------------------- 626

  Fly   946 TAPPATKEIWTEIEET------PLDNIDEFTELFSRQA---IAPVSKPKE-----------LKVK 990
                    :||||::|      .|::::.....:.||.   :...||.||           |||
  Rat   627 --------VWTEIDDTKVFKILDLEDLERTFSAYQRQQEFFVNNNSKQKEADAIDDALSSKLKV- 682

  Fly   991 RAKSIKVLDPERSRNVGIIWRSLHVPSSEIEHAIYHIDTS--------VVSLEALQHMSNIQATE 1047
              |.:.|:|..|::|..|:...|.:.:.||:.||..:|..        ...|:.:...|:|...|
  Rat   683 --KELSVIDGRRAQNCNILLSRLKLSNDEIKRAILTMDEQEDLPKDMLEQLLKFVPEKSDIDLLE 745

  Fly  1048 D---ELQRIKEAAGGDIPLDHPEQFLLDISLISMASERISCIVFQAEFEESVTLLFRKLETVSQL 1109
            :   ||.|:.:|          ::||.::|.|:...:|:..:.|:.:|.|.|..:..|:|.:...
  Rat   746 EHKHELDRMAKA----------DRFLFEMSRINHYQQRLQSLYFKKKFAERVAEVKPKVEAIRSS 800

  Fly  1110 SQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQADGFNLDILGKLKDVKSK-ESHTTLLHFIVRT 1173
            |::::.|..||.:..::|..|||||.|  |||.|.||.:..|.|:.|.||. :.:.||||::: |
  Rat   801 SEEVLRSSALKQLLEVVLAFGNYMNKG--QRGNAYGFKISSLNKIADTKSSIDKNITLLHYLI-T 862

  Fly  1174 YIAQRRKEGVHPLEIRLPIPEPADVERAAQMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEI 1238
            .:     |..:|..:.|. .|..|:.:||:::..|:.::|..| :..|....|..:...:..|:.
  Rat   863 IV-----ENKYPKVLNLS-EELRDIPQAAKVNMTELDKEISTL-RSGLKAVETELEYQKSQPPQP 920

  Fly  1239 MEPFKSKMEEFVEGADKSMAKLHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTN 1303
            .:.|.|.:.:|:..|..|.:.:...|.|.::||.:.::  ||..:|     .:..||:||..:..
  Rat   921 GDKFVSVVSQFITLASFSFSDVEDLLAEAKELFTKAVK--HFGEEA-----GKIQPDEFFGIFDQ 978

  Fly  1304 FTNDFKDIWKKEITSLLNELMKKSK---------QAQIESRRNVSTKVEK--------------- 1344
            |.....:. |:|     ||.|:|.|         :||::.:|....|:.|
  Rat   979 FLQAVTEA-KQE-----NENMRKRKEEEERRARLEAQLKEQRERERKMRKAKESSEESGEFDDLV 1037

  Fly  1345 ----SGRISLKERMLMRRSK 1360
                ||.:..|:...::|::
  Rat  1038 SALRSGEVFDKDLSKLKRNR 1057

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	108/458 (24%)
Daam1	XP_038968188.1	Drf_GBD	45..232	CDD:399398	40/205 (20%)
		Drf_FH3	235..439	CDD:368862	45/245 (18%)
		PRK12704	444..>513	CDD:237177	12/71 (17%)
		FH2	600..983	CDD:396655	113/476 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1922
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810