Protein Alignment capu and DAAM2

DIOPT Version :9

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: XP_006715102.3
• Gene: DAAM2 / 23500
• HGNCID: 18143
• Length: 1176
• Species: Homo sapiens
• Alignment Length: 1294
• Identity: 274/1294 - (21%)
• Similarity: 474/1294 - (36%)
• Gaps: 399/1294 - (30%)

  Fly   289 APNSPAESSPDEELMALQLGKKLAQ---VLGSGAGSPLTPG---------------------TME 329
            ||.|.:|...:|:  ::|.|..|:|   .|.|....|::.|                     ||.
Human    39 APQSWSEKEWEEK--SMQQGDGLSQHPHPLQSKCPRPISCGMDTDHNEDLGHLSADAPWPAVTMA 101

  Fly   330 P------------CAAGS------------------GSPLANGELFNVSKAKKVELQNLSSRFTA 364
            |            |..||                  .||:.|.|..|:..|:.|:..:|:.:...
Human   102 PRKRSHHGLGFLCCFGGSDIPEINLRDNHPLQFMEFSSPIPNAEELNIRFAELVDELDLTDKNRE 166

  Fly   365 AVTQTPP----------GVTSSTPNESGVTGPAGPLGATTSSPSLETQSTVIISFKSSQTPVQSQ 419
            |:...||          ......||:...:.|...:....|..::::    :.:|...:|.:::|
Human   167 AMFALPPEKKWQIYCSKKKEQEDPNKLATSWPDYYIDRINSMAAMQS----LYAFDEEETEMRNQ 227

  Fly   420 TNSAASENVED-DTAPLPLPPPPPGFGT------PTTPLLSSNVLKKVASFTVEK----SSAG-- 471
            .       ||| .||   |...|..|.|      ..|.||  |.|:.:...|.|.    |..|
Human   228 V-------VEDLKTA---LRTQPMRFVTRFIELEGLTCLL--NFLRSMDHATCESRIHTSLIGCI 280

  Fly   472 ----NNSSNPPNLCPTSDETTLLATPCSSSLTVATLPPEIAVGAAAGGVAGGAGSRRG------- 525
                |||....::....:..:.:|    .||.......::||....|.|....|..:.
Human   281 KALMNNSQGRAHVLAQPEAISTIA----QSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAMLH 341

  Fly   526 -SSYVPEKLSF--------AAYEKFEGQMLIKW-LISTMQSNPKSSSGDANQELFNTLALQFCNN 580
             ..|..|:..|        .:..::..::.:|. ::|.:.:...:.:|:.|        |:|..:
Human   342 YQVYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDN--------LEFRLH 398

  Fly   581 LKY----VGV------LKQISNEHLDCGFSPYEM------------YQWTH--TEQPTTSLPLTP 621
            |:|    :|:      |:|..|..||.....:||            :...|  |:..:....|..
Human   399 LRYEFLMLGIQPVIDKLRQHENAILDKHLDFFEMVRNEDDLELARRFDMVHIDTKSASQMFELIH 463

  Fly   622 GKLDKVAAWPFSSTPSGIRALESASLASLGAGGVAGSLATIATASTASSDNQKTLQQILKK---- 682
            .||....|:|                          .|.::.         ...||...|:
Human   464 KKLKYTEAYP--------------------------CLLSVL---------HHCLQMPYKRNGGY 493

  Fly   683 --------RLLNCTTLAEVHAVVNELLSSVDEPPRRP-----SKRCVNLTELLNASEATVY---- 730
                    |:|....|.:...|         :|...|     .|..||:  |:|.:|...:
Human   494 FQQWQLLDRILQQIVLQDERGV---------DPDLAPLENFNVKNIVNM--LINENEVKQWRDQA 547

  Fly   731 -EYNKTGAE---GCVKSFTDAETQT-ESEDCEGTCKCGQSSTKVSDNESAKEDGEKPHAVAPPPP 790
             ::.|...|   ...:...:.||:| |.|:...|....:........|..:..|:....||....
Human   548 EKFRKEHMELVSRLERKERECETKTLEKEEMMRTLNKMKDKLARESQELRQARGQVAELVAQLSE 612

  Fly   791 PPPPPLHAFVAPPPPPPPP------------PPPPPPLANYGAPPPPPPP-PPGSGSAPPPPPPA 842
            ....|    |:.||||..|            |||||||.....||||||| |||   .||.||.|
Human   613 LSTGP----VSSPPPPGGPLTLSSSMTTNDLPPPPPPLPFACCPPPPPPPLPPG---GPPTPPGA 670

  Fly   843 PIEGGGGIPPPPPPMSASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRPLYWTRIVT 907
            |...|.|:|.|..|.   ||    |..||              .:|....|..|::...|.::
Human   671 PPCLGMGLPLPQDPY---PS----SDVPL--------------RKKRVPQPSHPLKSFNWVKL-- 712

  Fly   908 SAPPAPRPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNI---DEF 969
                                           |....|.|       :|.||::..:..|   ::|
Human   713 -------------------------------NEERVPGT-------VWNEIDDMQVFRILDLEDF 739

  Fly   970 TELFS-----RQAIAPVSKPKE--------LKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSEIE 1021
            .::||     ::.|...|:.||        |..::.|.:.|:|..|::|..|:...|.:.:.||.
Human   740 EKMFSAYQRHQELITNPSQQKELGSTEDIYLASRKVKELSVIDGRRAQNCIILLSKLKLSNEEIR 804

  Fly  1022 HAIYHIDTSV-VSLEALQHM-------SNIQATEDELQRIKEAAGGDIPLDHPEQFLLDISLISM 1078
            .||..:|... ::.:.|:.:       |:|...|:....|:..|..|       :||.::|.|..
Human   805 QAILKMDEQEDLAKDMLEQLLKFIPEKSDIDLLEEHKHEIERMARAD-------RFLYEMSRIDH 862

  Fly  1079 ASERISCIVFQAEFEESVTLLFRKLETVSQLSQQLIESEDLKLVFSIILTLGNYMNGGNRQRGQA 1143
            ..:|:..:.|:.:|:|.:.....|:|.:...|::|:.|:.|:.:..:||.:||:||.|  |||.|
Human   863 YQQRLQALFFKKKFQERLAEAKPKVEAILLASRELVRSKRLRQMLEVILAIGNFMNKG--QRGGA 925

  Fly  1144 DGFNLDILGKLKDVKSK-ESHTTLLHFIVRTYIAQRRKEGVHPLEIRLP--IPEPADVE---RAA 1202
            .||.:..|.|:.|.||. :.:.:|||:::..            ||...|  :..|::::   .||
Human   926 YGFRVASLNKIADTKSSIDRNISLLHYLIMI------------LEKHFPDILNMPSELQHLPEAA 978

  Fly  1203 QMDFEEVQQQIFDLNKKFLGCKRTTAKVLAASRPEIMEP---FKSKMEEFVEGADKSMAKLHQSL 1264
            :::..|:::::.:|.:..    |.....|...|.::.||   |...|.:|:..:..|.::|...|
Human   979 KVNLAELEKEVGNLRRGL----RAVEVELEYQRRQVREPSDKFVPVMSDFITVSSFSFSELEDQL 1039

  Fly  1265 DECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELMKKSKQ 1329
            :|.||.|.:.:  .||....     ::..||:||..:..|...|.:. ::::.::.....::.::
Human  1040 NEARDKFAKAL--MHFGEHD-----SKMQPDEFFGIFDTFLQAFSEA-RQDLEAMRRRKEEEERR 1096

  Fly  1330 AQIES-------------RRNV---STKVE------------KSGRISLKERMLMRRSK 1360
            |::|:             :|.|   .:.:|            :||.:..|:...::||:
Human  1097 ARMEAMLKEQRERERWQRQRKVLAAGSSLEEGGEFDDLVSALRSGEVFDKDLCKLKRSR 1155

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	104/459 (23%)
DAAM2	XP_006715102.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910