Protein Alignment capu and inft-2

DIOPT Version :10

• Sequence 1: NP_001137784.1
• Gene: capu / 33611
• FlyBaseID: FBgn0000256
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: NP_506253.4
• Gene: inft-2 / 179786
• WormBaseID: WBGene00008848
• Length: 1120
• Species: Caenorhabditis elegans
• Alignment Length: 1203
• Identity: 249/1203 - (20%)
• Similarity: 409/1203 - (33%)
• Gaps: 393/1203 - (32%)

  Fly   359 SSRFTAAVTQTPPGVTSSTPNESGVTGPAGPLGATTSSPS---------------LETQSTVIIS 408
            :|:.:..:.|.|....:.||..|..:.|...|    |:||               ...|...:..
 Worm     7 NSKKSHRINQPPGSTKAKTPPFSDGSRPTSRL----SNPSDVENAGHADVPSKTKCNAQKPQVFG 67

  Fly   409 FKSSQTPVQSQTNSAASENVEDDTAPLPLPPPPPGF------GTPTTPLLSSNV----------- 456
            .||||..:.::..|..:.::.          |.|..      ..|.:.:.||.:
 Worm    68 NKSSQLNIAAKPRSNGAHSIS----------PEPNVSERCVDSLPVSSISSSRLDDTDVHIREMI 122

  Fly   457 -------------LKKVAS--------------FTVEK--------SSAGNNSSNPPNLCPTSDE 486
                         ||.:|.              ||:.|        |:...::...|......:|
 Worm   123 SEFRDEIGEETTRLKAIADINYMIGSTSSFFQRFTIRKKLHSYGFLSALAAHADRSPQSKAIDEE 187

  Fly   487 TTLLATPCSSSLTVATL------PPEIAVGAAAGGVAGGAGSRRGSSYVPEKLSFAAYEKFEGQM 545
            ..:.....|....:..|      |.||.                  :.:..|.|...:|.|.|
 Worm   188 VNMYLQSESRDARIMGLHDDNSQPIEIL------------------TRILSKTSDQQWENFIG-- 232

  Fly   546 LIKWLISTMQSNP---KSSSG------------------DANQELFNTLALQFCNNLKYVGVLKQ 589
                |:.|::.:.   .|.||                  |..|...|....:...|  :.|:.::
 Worm   233 ----LLETIEKSTDIGASISGLRVSCSSNVLTKDSETQTDVVQRKLNKERREPSRN--FHGIPEE 291

  Fly   590 ISNEHLDCGFSPYEMYQWTHTEQPTTSLPLTPGKLD---KVAAWPFSSTPSGIRALESASLASLG 651
            .:   :.|.:|..:......:..||     ||..:|   .:..|        :.|::..:.:.:|
 Worm   292 SA---VFCDYSTSDDESKLSSPDPT-----TPNSIDSNINLKKW--------MTAMDLPAQSQIG 340

  Fly   652 AGGVAGSLATIATASTASSDNQKTLQQILKKRLLNCTTLAEVHAVVNELLSSVDEPPRRPSKRCV 716
             |..|...:..:| ||.|||:...|..:      :.|||    .|:.|:||       ..::.|.
 Worm   341 -GNHAFFQSNFST-STFSSDDDGPLSPV------HDTTL----QVITEVLS-------EEAESCE 386

  Fly   717 NLTELLNASEATVYEYNKTGAEGCVKSFTDAETQTESEDCEGTCKCGQSSTKVSDNESAKEDGEK 781
            ..|. |.||.:.|:. :|...     :|.|..|.....|..|      .|..::.:....|.|:.
 Worm   387 MHTG-LEASPSAVFP-DKANI-----AFIDESTSASPLDGLG------FSDILTMSFEMIETGKM 438

  Fly   782 PHAVAP-----PPPPPPP----PLHAFVAPPP------------PPPPPP-----------PPPP 814
            ..|:||     ||||.||    ||....||||            ||||||           ||||
 Worm   439 NSAIAPINANAPPPPGPPSSLLPLINTNAPPPPPMPSINGHAPNPPPPPPLLGIAPMSTNAPPPP 503

  Fly   815 PL-----ANYGAPPPPPPPPPG-SGSAPPPPPPAPIE-------------GGGGIPPPPPPMS-- 858
            |:     .:.|||.||||||.| :...||||||.|::             ||...||||||.|
 Worm   504 PMPGMAPLSTGAPTPPPPPPVGMANGGPPPPPPLPLDLLKGAVAGLKSVPGGPPPPPPPPPPSFM 568

  Fly   859 --------ASPSKTTISPAPLPDPAEGNWFHRTNTMRKSAVNPPKPMRPLY--WTRIVTSAPPAP 913
                    .||..:|   :|:..|.          :.||||...|..:..:  |.::......|.
 Worm   569 FNGKVPNAFSPGTST---SPVLSPG----------VVKSAVVYRKQKKTAFVRWPKLTMQMQDAG 620

  Fly   914 RPPSVANSTDSTENSGSSPDEPPAANGADAPPTAPPATKEIWTEIEETPLDNID----------- 967
            ...:.:...|..|:..:..:|                      ..||.|:..::
 Worm   621 TVFNDSLCVDFNEDERTKMEE----------------------VFEEAPVKQLNRKIAGSVGRAF 663

  Fly   968 -----------EFTELFSRQAIAP--VSKPKELKVKRAKSIKVLDPERSRNVGIIWRSLHVPSSE 1019
                       ||..:.:|....|  :..||.|.::..  ||.|.|              :..::
 Worm   664 GKSLRATTSSSEFNPMSARSPTNPQVLVSPKALTIEIL--IKKLKP--------------MEFTQ 712

  Fly  1020 IEHAIYHIDTSVVSLEALQHMSNIQATEDELQ---RIKEAAGGDIPLDH-PEQFLLDISLISMAS 1080
            :...:...||..:.::.:..::|....:.||.   :::.|.     |.| .:||...|:......
 Worm   713 LIEKLDANDTEGIKVDLMTTLNNNFPDKVELDPFLKVEYAT-----LTHASDQFCWHIARNKHLR 772

  Fly  1081 ERISCIVFQAEFEESVTLLFRKLETVSQLSQ---QLIESEDLKLVFSIILTLGNYMNGGNRQRGQ 1142
            .||...:    .:|:||....|.::..:|.|   ||...|.::::....|..|||:|.|: ...:
 Worm   773 LRIELFI----SKENVTAEIGKFQSQIELLQTGCQLARGEIVQVLLRKCLQYGNYLNQGS-MFAE 832

  Fly  1143 ADGFNLDILGKLKDVKSKESHTT--LLHFIVRTYI---------AQRRKEGVHPLEIRLPIPEPA 1196
            |.||....|.:|..:|.|..||:  |:..|| .|.         .|.|...|.||.::
 Worm   833 AAGFQFSYLIQLLQMKGKGQHTSVRLVDLIV-AYCDLATAEVEEVQSRMGSVRPLNLK------- 889

  Fly  1197 DVERAAQMDFEEVQQQIFDLNKKFLGCKRTTAK--VLAASRPEIMEPFKSKMEEFVEGADKSMAK 1259
                    |.|:|..|:....:|..|..|::::  ::||     .|||.::..|.::.....::.
 Worm   890 --------DLEDVVGQVQRSIRKLEGQLRSSSEETLIAA-----YEPFVNQTNEKLQNVQNGLSD 941

  Fly  1260 LHQSLDECRDLFLETMRFYHFSPKACTLTLAQCTPDQFFEYWTNFTNDFKDIWKKEITSLLNELM 1324
            |     :.|:..|:..           |.....|....||..........|..|:..|.  |.|.
 Worm   942 L-----KARETELQVY-----------LCAGNMTLQAIFETLEQSMKIVSDAVKQAATK--NRLT 988

  Fly  1325 KKSKQAQIESRRNVSTKVEKSGRISLKERMLMR 1357
            :.|....:.: .:||.:..:.|.:..::.|.::
 Worm   989 RASSLVTLPT-SSVSRRSLREGEVLSRQSMALK 1020

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
capu	NP_001137784.1	FH2	888..1315	CDD:214697	92/472 (19%)
inft-2	NP_506253.4	FH2	597..975	CDD:396655	86/462 (19%)