DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cep97 and LRRC46

DIOPT Version :9

Sequence 1:NP_608811.2 Gene:Cep97 / 33610 FlyBaseID:FBgn0031575 Length:806 Species:Drosophila melanogaster
Sequence 2:XP_005257832.1 Gene:LRRC46 / 90506 HGNCID:25047 Length:330 Species:Homo sapiens


Alignment Length:319 Identity:70/319 - (21%)
Similarity:112/319 - (35%) Gaps:99/319 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    87 LSIEGLKECIHLR----------VLNLEGNNIKTIEHLNTNVNLECLNLADNSIGSISDMSYLRN 141
            ||:.|.::|..:.          .:|.......|::.|.|      :.|....|.:|.::..|:|
Human    18 LSLVGTQQCCGMNEWVDGTSAFFSMNDSKGRFHTLDELQT------VRLDREGITTIRNLEGLQN 76

  Fly   142 LKELYLHGNRLTHLRQCDKCLPTSLETLTLAKNSINDLNEICTLSHL------------------ 188
            |..|||.||::..:... .|:| ||..|:||.|.|..:..:..|..|                  
Human    77 LHSLYLQGNKIQQIENL-ACIP-SLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLKLDEF 139

  Fly   189 -SNLLSISIADNPCVTMINSLDGFDYRPFVLNWCMSLKYIDGFVVDPIESLKAEWLYSQGRGRQF 252
             .:||.::::.|.|...    ||  ||..|......|..:||      :.:...|:..:    :.
Human   140 PQSLLILNLSGNSCTNQ----DG--YRELVTEALPLLLDLDG------QPVVERWISDE----ED 188

  Fly   253 RVGEQQGLAKYLSSVCPLVG--KALENENDRKLRLILSKAQHHQRQ-----------LQEEIMD- 303
            .....:...:.....|...|  |.||.|        ||:.:.|::|           :|..:.| 
Human   189 EASSDEEFPELSGPFCSERGFLKELEQE--------LSRHREHRQQTALTEHLLRMEMQPTLTDL 245

  Fly   304 --------NANSSASTSP----------------SSHRKKPTSRIQSPRFSRLSGRQGS 338
                    ..:||.|.:|                ||..|||.|.|.....|...||:|:
Human   246 PLLPGVPMAGDSSPSATPAQGEETVPEAVSSPQASSPTKKPCSLIPRGHQSSFWGRKGA 304

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cep97NP_608811.2 leucine-rich repeat 11..31 CDD:275380
leucine-rich repeat 32..53 CDD:275380
LRR_RI <49..189 CDD:238064 30/130 (23%)
LRR_4 76..115 CDD:289563 6/37 (16%)
leucine-rich repeat 76..97 CDD:275380 4/9 (44%)
LRR_8 97..152 CDD:290566 15/64 (23%)
LRR_4 97..137 CDD:289563 7/49 (14%)
leucine-rich repeat 98..119 CDD:275380 4/30 (13%)
leucine-rich repeat 120..141 CDD:275380 4/20 (20%)
LRR_8 140..200 CDD:290566 20/78 (26%)
leucine-rich repeat 142..165 CDD:275380 8/22 (36%)
leucine-rich repeat 166..190 CDD:275380 8/42 (19%)
IQ 581..599 CDD:197470
LRRC46XP_005257832.1 LRR_8 54..109 CDD:290566 21/62 (34%)
leucine-rich repeat 55..76 CDD:275378 6/26 (23%)
LRR_4 75..115 CDD:289563 16/41 (39%)
leucine-rich repeat 77..98 CDD:275378 8/22 (36%)
LRR_8 97..151 CDD:290566 12/54 (22%)
LRR_4 97..135 CDD:289563 10/38 (26%)
leucine-rich repeat 99..120 CDD:275378 7/20 (35%)
leucine-rich repeat 121..142 CDD:275378 1/20 (5%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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