DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cep97 and TbCMF46

DIOPT Version :9

Sequence 1:	NP_608811.2	Gene:	Cep97 / 33610	FlyBaseID:	FBgn0031575	Length:	806	Species:	Drosophila melanogaster
Sequence 2:	NP_609325.2	Gene:	TbCMF46 / 34318	FlyBaseID:	FBgn0032163	Length:	566	Species:	Drosophila melanogaster

Alignment Length:	161	Identity:	48/161 - (29%)
Similarity:	82/161 - (50%)	Gaps:	18/161 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 KQDDAHSIRQL-----------ILDENELQKIDNIDSYLKIETLSLARNQLLRMYGVCRLHCLRE 78
            |:.:|..:.||           .|:...:.:||::.....:..|.|..|::..:..:..|..|::
  Fly    51 KKGEARRLHQLEPVVYDRITTMRLEFKNILRIDHLWMMPNLTKLCLNCNKIEVIEHLEMLTALKD 115

  Fly    79 LNLSFNGILSIEGLKECIHLRVLNLEGNNIKTIEHLNTNVNLECLNLADNSIGSISDMSYLR--- 140
            ||||||.|..||.|::.:.|..|:|..|.|:.||:::|..||..|::.:|.|.::..:..||
  Fly   116 LNLSFNYITRIENLEKLVKLEKLSLFSNRIRKIENIHTLQNLVILSIGNNLIDTVEGIERLRFVS 180

  Fly   141 NLKELYLHGNRLTHLRQCDKCLPTSLETLTL 171
            :||.|.|.||.:.  :|.|  .|.||..:.:
  Fly   181 SLKVLNLEGNPIA--KQPD--FPLSLYVIAI 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cep97	NP_608811.2	leucine-rich repeat	11..31	CDD:275380	2/5 (40%)
		leucine-rich repeat	32..53	CDD:275380	5/31 (16%)
		LRR_RI	<49..189	CDD:238064	41/126 (33%)
		LRR_4	76..115	CDD:289563	18/38 (47%)
		leucine-rich repeat	76..97	CDD:275380	11/20 (55%)
		LRR_8	97..152	CDD:290566	21/57 (37%)
		LRR_4	97..137	CDD:289563	13/39 (33%)
		leucine-rich repeat	98..119	CDD:275380	8/20 (40%)
		leucine-rich repeat	120..141	CDD:275380	6/23 (26%)
		LRR_8	140..200	CDD:290566	12/35 (34%)
		leucine-rich repeat	142..165	CDD:275380	9/22 (41%)
		leucine-rich repeat	166..190	CDD:275380	1/6 (17%)
		IQ	581..599	CDD:197470
TbCMF46	NP_609325.2	leucine-rich repeat	69..90	CDD:275378	3/20 (15%)
		LRR_8	89..145	CDD:290566	19/55 (35%)
		LRR_4	89..131	CDD:289563	15/41 (37%)
		leucine-rich repeat	91..112	CDD:275378	4/20 (20%)
		leucine-rich repeat	113..134	CDD:275378	11/20 (55%)
		LRR_8	134..192	CDD:290566	21/57 (37%)
		LRR_4	134..174	CDD:289563	13/39 (33%)
		leucine-rich repeat	135..156	CDD:275378	8/20 (40%)
		leucine-rich repeat	157..181	CDD:275378	6/23 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447153
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45973
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940