Protein Alignment Cep97 and Cep97

DIOPT Version :10

• Sequence 1: NP_608811.2
• Gene: Cep97 / 33610
• FlyBaseID: FBgn0031575
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_001100566.1
• Gene: Cep97 / 304007
• RGDID: 1307400
• Length: 845
• Species: Rattus norvegicus
• Alignment Length: 922
• Identity: 268/922 - (29%)
• Similarity: 422/922 - (45%)
• Gaps: 230/922 - (24%)

  Fly     9 EKHVLNLSKQKLKK----VPKQDDAHSIRQLILDENELQKIDNIDSYLKIETLSLARNQLLRMYG 69
            |..|:|.|.|.|:|    :|...|.|:   ||||:|::.|::|::...::..||:|.|:|:||.|
  Rat    14 EGSVVNWSGQGLQKLGANLPCDADVHT---LILDKNQIIKLENLEKCKQLIQLSVANNRLVRMMG 75

  Fly    70 VCRLHCLRELNLSFNGILSIEGLKECIHLRVLNLEGNNIKTIEHLNTNVNLECLNLADNSIGSIS 134
            |.:|..||.|||..|.|..:||||:.:||..|||.|||:||:|.:|:...|:.|:|:||:|..|.
  Rat    76 VAKLTQLRVLNLPHNSIGCMEGLKDLVHLEWLNLAGNNLKTMEQINSCSALQHLDLSDNNIPQIG 140

  Fly   135 DMSYLRNLKELYLHGNRLTHLRQCDKCLPTSLETLTLAKNSINDLNEICTLSHLSNLLSISIADN 199
            |:|.|..||.|.||||.:|.||.....||.:|..|:||:|.|.|||||..|:.||.|..:||.:|
  Rat   141 DVSKLTALKTLLLHGNIITSLRMAPAYLPRNLSILSLAENEIRDLNEISFLASLSELEQLSIMNN 205

  Fly   200 PCVTMINSLDGFDYRPFVLNWCMSLKYIDGFVVDPIESLKAEWLYSQGRGRQFRVGEQQGLAKYL 264
            |||....|:.||||||::::||::|:.:||:|:...||||||||||||:||.:|.|:...|.:||
  Rat   206 PCVMATPSIPGFDYRPYIVSWCLNLRVLDGYVISQKESLKAEWLYSQGKGRSYRPGQHVQLVQYL 270

  Fly   265 SSVCPLVGK-ALENENDRKLRLILSKAQHHQRQLQEEIMDNANSSASTSPSSHRKKPTSRIQS-- 326
            ::||||:.. .|:...|.||..||||.:.|||||..:   :.|...|         |.:.:::
  Rat   271 ATVCPLISALGLQTAEDAKLEKILSKQRFHQRQLMNQ---SQNEELS---------PIAAVETRV 323

  Fly   327 PRFSRLSG-----RQGSPESMVNSYHGNSSNNS---IVSDNG-STNHSLQMSIS--LIENIKNDG 380
            ||....|.     ::..|...:||:.|:|||:.   .|.:|. :|.|:.:.|.:  .:|:|:.|.
  Rat   324 PRTPECSSPVQDFQESEPVLQINSWVGSSSNDDQLYAVKNNFLATTHATRYSRNDLHLEDIQTDE 388

  Fly   381 EGFSLAGSGMSSSVTTKTYNSTESTPRNITPNPYNDQTFISQTPSGGPLAAASKMVPVPETLMSP 445
            :  .|..|.:||                       :.||         :..||.:.||     ||
  Rat   389 D--KLNCSLLSS-----------------------ESTF---------MPVASGLSPV-----SP 414

  Fly   446 DVCPAAVAQRVTVTALNPQLHK-------TKINKNKDNKLNLPRVRS------PQLKRNQSPTSS 497
            .|       .:.:..:|..|..       ||..:::|  |:..|.:|      ..|||..|...:
  Rat   415 TV-------ELRLQGINLGLEDDDGTDEFTKGLEHQD--LDKDREKSLWDSDVQMLKRKISTEGN 470

  Fly   498 PRRMANKCSADNMQAPEKLQQSAVLAD------SGGFS---TDDDGEQI----NIEKLRAIRKMA 549
            .       .|..:..|:....:|:|.:      |||.|   |:.:.|::    ..||...  ::.
  Rat   471 E-------EAGLLPCPKSSIITALLKEDNHSLTSGGHSVSHTEPNREEVMSPTTSEKFPC--RIF 526

  Fly   550 AQKQQQMHQEQLKQQVDNNLNCQDRLIEHVTESSAVTIQKMWRGYHTR--KKTNKDIAERLQRRR 612
            .|:...:.|:::..|   .||           ::|..:|..|||::||  ....|.:...::.||
  Rat   527 TQRPVALGQDKVTLQ---KLN-----------AAATKLQACWRGFYTRNYNPQAKGVRYEIRLRR 577

  Fly   613 TQEYIEQLGKDMLLTKAQLENERKIQQLQMQAINALWKKVSTME--------------------- 656
            .||:|..|..::...:.:.:.||....:|.:|:..||.:|..::
  Rat   578 MQEHIVCLTDEVRRLRKERDEERVKNFVQEEAVRVLWNEVRALQAWQQTVEQRLVSWHSDVPPIS 642

  Fly   657 ---VDPKGIPAAAEQGEDSNGGGSGHLSLDQNSA-AVVNDLAKR------------CTMLTDQVQ 705
               |.||  |....|.:|.        |.||||. .::.|.|.:            .:.||:||.
  Rat   643 STLVSPK--PPLLPQHQDP--------SSDQNSDWLIIEDDAPQEKSVPDFPDSGFHSSLTEQVH 697

  Fly   706 MLQ---------------SSIGTIVNCLTMVCNLPQDAIKKQAEIIDCS---------STQTDLI 746
            .||               |::|...:.:..|.:...:|..:  |..|||         :|.....
  Rat   698 CLQDSLDFEKSSVESSENSALGNSADTVKYVKDPDSEATAE--EHSDCSKESSTSEQDNTLLQQY 760

  Fly   747 AVHTPQIEDLTNFPFTKTRPSTLALESKH--------------EAALACPKIDELNDVDLKETQE 797
            .....|::|..:    :..|..:|.::|.              ||..|.|.:.|    ::.:|.|
  Rat   761 LASVQQLDDADD----RAGPDDMAGDNKRLLACSPERLGASDSEAHRASPTLQE----EISQTPE 817

  Fly   798 D---SENLDKDP 806
            :   :|.:...|
  Rat   818 NCKLNEEVQGQP 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cep97	NP_608811.2	leucine-rich repeat	11..31	CDD:275380	8/23 (35%)
		PPP1R42	13..229	CDD:455733	101/219 (46%)
		leucine-rich repeat	32..53	CDD:275380	7/20 (35%)
		leucine-rich repeat	76..97	CDD:275380	11/20 (55%)
		leucine-rich repeat	98..119	CDD:275380	11/20 (55%)
		leucine-rich repeat	120..141	CDD:275380	10/20 (50%)
		leucine-rich repeat	142..165	CDD:275380	12/22 (55%)
		leucine-rich repeat	166..190	CDD:275380	13/23 (57%)
		IQ	581..599	CDD:197470	7/19 (37%)
Cep97	NP_001100566.1	leucine-rich repeat	17..37	CDD:275380	9/23 (39%)
		PPP1R42	18..242	CDD:455733	104/227 (46%)
		leucine-rich repeat	38..59	CDD:275380	7/20 (35%)
		leucine-rich repeat	60..81	CDD:275380	10/20 (50%)
		leucine-rich repeat	82..103	CDD:275380	10/20 (50%)
		leucine-rich repeat	104..125	CDD:275380	10/20 (50%)
		leucine-rich repeat	126..149	CDD:275380	10/22 (45%)
		leucine-rich repeat	150..171	CDD:275380	10/20 (50%)
		leucine-rich repeat	172..196	CDD:275380	13/23 (57%)
		IQCD	540..>560	CDD:467745	4/23 (17%)