DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cep97 and Drc3

DIOPT Version :9

Sequence 1:NP_608811.2 Gene:Cep97 / 33610 FlyBaseID:FBgn0031575 Length:806 Species:Drosophila melanogaster
Sequence 2:NP_001013879.1 Gene:Drc3 / 287371 RGDID:1309150 Length:523 Species:Rattus norvegicus


Alignment Length:551 Identity:112/551 - (20%)
Similarity:200/551 - (36%) Gaps:145/551 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 DENELQKIDNIDSYLKIETLSLARNQLLRMYGVCRLHCLRELNLSFNGILSIEGLKECIHLRVLN 102
            :..:|.|.:.| .:..:..|.|....:||:..:.:...||:|.|:.|.|..||||:...||..|:
  Rat    30 EAGQLAKQEGI-LFKDVLALQLDFQNILRIDNLWQFENLRKLQLNNNIIERIEGLENLTHLVWLD 93

  Fly   103 LEGNNIKTIEHLNTNVNLECLNLADNSIGSISDMSYLRNLKELYLHGNRLTHLRQCDKCLPTSLE 167
            |..|||:.||.|:|.||||.|:|:.|.|..|..:..|.|                        |:
  Rat    94 LSFNNIEAIEGLDTLVNLEDLSLSHNRISKIDSLDPLVN------------------------LQ 134

  Fly   168 TLTLAKNSINDLNEICTLSHLSNLLSISIADNPCVTMINSLDGFDYRPFVLNWCMSLKYIDGFVV 232
            .|:|..|.||::..|..|.....|.::|::.||.      .:..:|:.|:..:...|.|:|...|
  Rat   135 VLSLGNNQINNMMNIIYLRRFPCLRTLSLSGNPV------SEAEEYKVFIYAYLPDLVYLDFRRV 193

  Fly   233 D----PIESLKAEWLYSQGRGR----QFRVGEQQGLAKYLS------------------------ 265
            |    .:..:|.::...:.:.|    |.|:.|:|...:.|:                        
  Rat   194 DEQAREVAKMKHQYSIDELKHREALMQIRLEEEQAKQQKLAEHKMAFVEHLNGPFLFDSMYSDDV 258

  Fly   266 -----SVCPLVGKALENENDRKLRLILS-----KAQHHQRQLQEEIMDNANSSASTSPSSHRKKP 320
                 |..|.||:.||...|:.:.:.|:     .:|..:|:::.:..:.....|........|..
  Rat   259 EGNKLSYLPGVGELLEAYKDKFVIICLNIFEYGLSQQEKRKIELDTFNECIQEAIQENQDQGKLK 323

  Fly   321 TSRIQSPRFSRLSGRQGSPESMVNSYHGNSSNNSIVSDNGSTNHSLQMSISLIENIKNDGEGFSL 385
            .::.:......|:..:...:...........|.||..   ..|..:.:.:.|:|.::        
  Rat   324 IAKFEEKHLLNLNAIREESDLFTMEQKLTECNESITE---LFNTLMILEMQLVEQLE-------- 377

  Fly   386 AGSGMSSSVTTKTYNSTESTPRNITPNPYNDQT--FISQTPSGGPLAAA---------SKMVPVP 439
                       :|.|..|   ||||     |..  ||....|   |.|.         .|::.:.
  Rat   378 -----------ETINVFE---RNIT-----DLVGLFIENVQS---LIAQCRDLENHHHEKLLEIA 420

  Fly   440 ----ETLMS-------PDVCPAAVAQRVTV---TALNPQLHKTKINKNKDNKLN---------LP 481
                |.::.       ||...|....:.|:   ...:..:|..||:..:|..:.         :.
  Rat   421 INTLEKILKGEMDEDLPDDVRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTGVNSWCAHLVD 485

  Fly   482 RVRSPQLKRNQSPTSSPRRMANKCSADNMQA 512
            ::...::.||:.......:.     .|:||:
  Rat   486 KIHKDEIMRNRKRVKEINQF-----VDHMQS 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cep97NP_608811.2 leucine-rich repeat 11..31 CDD:275380
leucine-rich repeat 32..53 CDD:275380 3/14 (21%)
LRR_RI <49..189 CDD:238064 44/139 (32%)
LRR_4 76..115 CDD:289563 19/38 (50%)
leucine-rich repeat 76..97 CDD:275380 10/20 (50%)
LRR_8 97..152 CDD:290566 22/54 (41%)
LRR_4 97..137 CDD:289563 20/39 (51%)
leucine-rich repeat 98..119 CDD:275380 10/20 (50%)
leucine-rich repeat 120..141 CDD:275380 8/20 (40%)
LRR_8 140..200 CDD:290566 11/59 (19%)
leucine-rich repeat 142..165 CDD:275380 0/22 (0%)
leucine-rich repeat 166..190 CDD:275380 8/23 (35%)
IQ 581..599 CDD:197470
Drc3NP_001013879.1 LRR 1 44..65 4/20 (20%)
leucine-rich repeat 48..66 CDD:275378 4/17 (24%)
LRR_4 65..105 CDD:289563 19/39 (49%)
LRR_8 66..121 CDD:290566 28/54 (52%)
LRR 2 66..87 10/20 (50%)
leucine-rich repeat 67..88 CDD:275378 10/20 (50%)
LRR_4 87..129 CDD:289563 20/41 (49%)
LRR 3 88..109 11/20 (55%)
leucine-rich repeat 89..110 CDD:275378 10/20 (50%)
LRR 4 110..131 8/20 (40%)
leucine-rich repeat 111..132 CDD:275378 8/20 (40%)
LRR 5 132..153 8/44 (18%)
leucine-rich repeat 158..169 CDD:275378 4/16 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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