Protein Alignment Cep97 and ccep-97

DIOPT Version :10

• Sequence 1: NP_608811.2
• Gene: Cep97 / 33610
• FlyBaseID: FBgn0031575
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_504289.1
• Gene: ccep-97 / 178871
• WormBaseID: WBGene00019842
• Length: 630
• Species: Caenorhabditis elegans
• Alignment Length: 711
• Identity: 170/711 - (23%)
• Similarity: 267/711 - (37%)
• Gaps: 210/711 - (29%)

  Fly     5 ESGEEKHVLNLSK---QK---LKKVPKQD--DAH--SIRQLILDENELQKIDNIDSYLKIETLSL 59
            |..|.|| |.:|.   ||   :|..||..  ||.  .|.:.|.|.|          |..:| |.|
 Worm    75 EYSEVKH-LKISGNCFQKFTYIKLFPKCQIIDARDCQINKFIADFN----------YNLLE-LHL 127

  Fly    60 ARNQLLRMYGVCRLHCLRELNLSFNGI-----LSIEGLKECIHLRVLNLEGNNIKTIEHLNTNVN 119
            |||||.....:.|...|:.|:||.|.|     .|::      :|.:|||.||.:..|..|:..|.
 Worm   128 ARNQLKETNQLGRFENLKILDLSNNLIEPPVSFSLK------NLEILNLSGNFLNEIPDLSKCVA 186

  Fly   120 LECLNLADNSIGSISDMSYLRNLKELYLHGNRLTHLRQCDKCLPTSLETLTLAKNSINDLNEICT 184
            |:.::||||   .|||::.:..|                  ..||:|:.|.::.|||.||::...
 Worm   187 LQTISLADN---KISDLTTITKL------------------ICPTNLKNLDISSNSIEDLSQFSV 230

  Fly   185 LSHLSNLLSISIADNPCVTMINSLDGFDYRPFVLNWCM-SLKYIDGFVVDPIESLKAEWLYSQGR 248
            ||....|....:|.||.:|.:...|.||||.::...|. .|..|||..::.....:.|||..||.
 Worm   231 LSTFKKLEEFVVAGNPSITSVLDSDLFDYRSYIFACCSEQLHTIDGQKIEDQVQTEGEWLALQGS 295

  Fly   249 GRQFRVGEQQGLAKYLSSVCPLVG----------KALENENDRKLRLILSKAQHHQRQLQEEIMD 303
            .::...|....|.:.::|..|..|          ||||.....|:      .:.|..:..|:...
 Worm   296 IKKIGPGNHDALCQQIASHFPDSGPPTPAQKSCHKALEKRRSMKV------PEKHLEEFSEDTDR 354

  Fly   304 NANSSASTSPSSHRKKPTSRIQSPRFSRLSGRQG---SPESMVNSYHGNSSNNSIVSDNGSTNHS 365
            ..||                :.|| |...:|:.|   :||:       :.|:..|     ..|.:
 Worm   355 TENS----------------VYSP-FREWNGKIGALMTPEA-------SGSSRRI-----PVNKN 390

  Fly   366 LQMSISLIENIKNDGEGFSLAGSGMSSSVTTKTYNSTESTPRNITPNPYNDQTFISQTPSGGPLA 430
            |:| .|..|..||                  ||:.....|    :||.|.:    :..|.|...:
 Worm   391 LRM-CSPPEARKN------------------KTFKFQNET----SPNRYPE----NFRPLGSTRS 428

  Fly   431 AASKMVPVPETLMSPDVCPAAVAQRVTVTALNPQLHKTKINKNKDNKLNLPRVRSPQLKRNQSPT 495
            .:::.|          :|.:......||             ..:.....|||:....|:|.:
 Worm   429 ISTETV----------ICSSRTEVSFTV-------------DGRSESTPLPRIDCAPLERKE--- 467

  Fly   496 SSPRRMANKCSADNMQAPEKLQQSAVLADSGGFSTDDDGEQINIEKLRAIRKMAAQKQQQMHQEQ 560
                           |.||:....:| ||......:.|||         :::..|..::.:  ::
 Worm   468 ---------------QEPEQRHTPSV-ADVTYVGEESDGE---------LKQKVAYLEKSV--DE 505

  Fly   561 LKQQVDNNLNCQDRLIEHVTESSAVTIQKMWRGYHTRKKTNKD-IAERLQRRRTQEYIEQLGKDM 624
            ||.|.:|.....|||::.:.|..|...: ||:.......|.:: |:..|.......::.|:..||
 Worm   506 LKIQNENLTAINDRLVDTLEEFKAEQAE-MWKAIRNMIPTPQNVISNFLVENEDGHHVHQVRWDM 569

  Fly   625 LLTK-----------AQLE---NERKIQQL--------QMQAI--NALWKKVS-TMEVDPK 660
            ...|           .|::   |..:|..|        |:||:  |.|..::| .:.:.||
 Worm   570 PAVKEFRIFVDGNQCGQIKGKNNSARITDLTSNEPHTVQIQAVGNNGLHGEISKKLHIVPK 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cep97	NP_608811.2	leucine-rich repeat	11..31	CDD:275380	10/29 (34%)
		PPP1R42	13..229	CDD:455733	72/231 (31%)
		leucine-rich repeat	32..53	CDD:275380	5/20 (25%)
		leucine-rich repeat	76..97	CDD:275380	7/25 (28%)
		leucine-rich repeat	98..119	CDD:275380	8/20 (40%)
		leucine-rich repeat	120..141	CDD:275380	8/20 (40%)
		leucine-rich repeat	142..165	CDD:275380	2/22 (9%)
		leucine-rich repeat	166..190	CDD:275380	9/23 (39%)
		IQ	581..599	CDD:197470	4/17 (24%)
ccep-97	NP_504289.1	LRR	<57..293	CDD:443914	81/256 (32%)
		leucine-rich repeat	57..78	CDD:275380	1/2 (50%)
		leucine-rich repeat	122..143	CDD:275380	9/21 (43%)
		leucine-rich repeat	144..164	CDD:275380	7/25 (28%)
		leucine-rich repeat	165..186	CDD:275380	8/20 (40%)
		leucine-rich repeat	187..211	CDD:275380	10/44 (23%)
		leucine-rich repeat	212..236	CDD:275380	9/23 (39%)
		leucine-rich repeat	237..256	CDD:275380	5/18 (28%)