Protein Alignment TTLL4B and PBY1

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_009652.2
• Gene: PBY1 / 852391
• SGDID: S000000298
• Length: 753
• Species: Saccharomyces cerevisiae
• Alignment Length: 750
• Identity: 156/750 - (20%)
• Similarity: 259/750 - (34%)
• Gaps: 231/750 - (30%)

  Fly   175 NSSTPK-------VAATPSNVPVVANSVLQSEPYKKVQMLLKRAREEAFAKHTAGNSAANGNGPK 232
            |:..||       :..||::...:...:|.:||:..|.......|..:.|..|:..:....
Yeast    95 NAEIPKDTIEWILIDGTPASCANIGLHLLSNEPFDLVLSGPNVGRNTSAAYITSSGTVGGA---- 155

  Fly   233 RSAHSPPIQAKVPPSNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEEKS----RLLTQNGL 293
                            |....|...|....|....|.....|.|..::..::|    :.|.:|..
Yeast   156 ----------------MESVITGNTKAIAISWAYFNGLKNVSPLLMEKASKRSLDVIKHLVKNWD 204

  Fly   294 TKSAATALETSLYASL-------YANAPQNSQ-PQFHSPRIS---------GGDHVASYVGVSLN 341
            .|:...::...|..||       ||...:|.. |.|:.|.|:         .|:..:|   :|.|
Yeast   205 PKTDLYSINIPLVESLSDDTKVYYAPIWENRWIPIFNGPHINLENSFAEIEDGNESSS---ISFN 266

  Fly   342 ---KGAGHDNDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFFLEEDNT-----ETRQSKHTRLL 398
               |...|.             |.|:|.|      ||        :|.|     |..:|:...:.
Yeast   267 WAPKFGAHK-------------DSIHYMD------EY--------KDRTVLTDAEVIESEMISVT 304

  Fly   399 PQKTPSK------ESVRTTDSEASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVL 457
            |.|...|      ..::.|:.|.:: .:...::..|:.|....|...| ||
Yeast   305 PMKATFKGVNHLLGELKLTEEENNL-SKTNNLIVVSIDPMEYIYKPLT-HA-------------- 353

  Fly   458 KWKLSPVMPKIVKRVVLNSGFRIIKNTTDW-MAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRK 521
               |...:|::          .|:.|..:: ....||.||      :..:..|..:.....:...
Yeast   354 ---LKKYLPQV----------EIVSNLPEFDNGGCEKEMK------VFHYGDYEQLDMDKLMELP 399

  Fly   522 DTMWRSIYNNMKKFGKKEF--------------GFMQKSYI------------MPDDLE---SLR 557
            :..:.:.|...|...:|.|              ..::|:|:            :.|.|:   .||
Yeast   400 NNYFTNSYIYRKALIRKHFLSHTIQTYTAKNPESILKKAYLESFTIDLDYAEFLDDALDENWELR 464

  Fly   558 QVWPKNASKLTKWIVKPPASARGTGIRIV------------------------------------ 586
            |.. :|.|:...|||||..|.:|.|||:.
Yeast   465 QEL-ENESQDKWWIVKPSMSDKGQGIRVFKTIEDLQAIFDSFDDEDSEAEESGNDDDADDVNGEF 528

  Fly   587 --NKWSQFPKDRPLVVQKYIERPLLI---NDNKFDMRLYVVLTSINPLRIYMYKDGLARFASV-- 644
              |......:.|..::|:|:..|||:   ::.||.:|.|||..  ..|::::|...||.||:.
Yeast   529 MDNNKVNISQLRHFIIQEYLTNPLLLASMDNRKFHIRCYVVCR--GDLQVFVYDRMLALFAAKPF 591

  Fly   645 ----KYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRL 705
                .|:..:::|.:...||||..:    |:..|::|.:..:     ..|:......|..|.|..
Yeast   592 VPLDPYAYSVTDLKDLECHLTNTCL----QSKKKDKDSSVLE-----FDSIEEIPNERKSNIKEQ 647

  Fly   706 WATLRNLVIKGIVSGESGLNRMYRQNVNFR--YNCFELFGFDVLLDENLVPWLLEINISPSLHSE 768
            ..::.|.|....|:    :||:     ||:  .|.||.:|.|.|:|.|....|||||..|.. .:
Yeast   648 IHSITNDVFLAAVN----VNRL-----NFQPLPNAFETYGVDFLIDSNYEVKLLEINAFPDF-KQ 702

  Fly   769 LPLDLHVKGPLIQAVLNTALYQVPPKLNE-RQQAD 802
            ...||  |..:.:...:|..|.|.|..|| |.:.|
Yeast   703 TGKDL--KNLIDELFDDTVKYCVTPIFNENRNKTD 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	86/372 (23%)
PBY1	NP_009652.2	surE	1..311	CDD:272899	51/265 (19%)
		TTL	389..732	CDD:397308	85/366 (23%)