Protein Alignment TTLL4B and Ttll7

DIOPT Version :9

• Sequence 1: NP_001260010.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_001289886.1
• Gene: Ttll7 / 70892
• MGIID: 1918142
• Length: 912
• Species: Mus musculus
• Alignment Length: 601
• Identity: 160/601 - (26%)
• Similarity: 263/601 - (43%)
• Gaps: 114/601 - (18%)

  Fly   431 PHVPP--YLNFTSHADKGPPMPAALHRVLKWKLSPVMPK-IVKRVVLNSGFRIIKNTTDWMA--- 489
            |.:|.  .:..:|..|.|..:|  ....:|.|:.....| |:...|..:.|.|::...|.|.
Mouse     2 PSLPQDGVIQGSSPVDLGTELP--YQCTMKRKVRKKKKKGIITANVAGTKFEIVRLVIDEMGFMK 64

  Fly   490 ----------VW-EKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKK---EF 540
                      :| :..::......::::|:.||.||...|.|||.:.|    ||.|..|.   ::
Mouse    65 TPDEDETSNLIWCDAAVQQEKITDLQNYQRINHFPGMGEICRKDFLAR----NMTKMIKSRPMDY 125

  Fly   541 GFMQKSYIMPDDLESLRQVWPKNASKLTK---WIVKPPASARGTGIRIVNKWSQFPKDRPLVVQK 602
            .|:.:::|.|.:.... |.:.|...|..|   :||||...|.|.||.::....:.|....|:||:
Mouse   126 TFVPRTWIFPSEYTQF-QNYVKELKKKRKQKTFIVKPANGAMGHGISLIRNGDKVPSQDHLIVQE 189

  Fly   603 YIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKY-SSELSNLDERCMHLTNYSIN 666
            |||:|.|:...|||:|:|:::||.:||:|::|.|||.|..:.|| ....|||.:..|||||||:|
Mouse   190 YIEKPFLMEGYKFDLRIYILVTSCDPLKIFLYHDGLVRMGTEKYIPPNESNLTQLYMHLTNYSVN 254

  Fly   667 KFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYR-- 729
            |.::.:.:||..:  :|.|.:::.....|:....:..:.|:.:..||:|.::..|..:...||
Mouse   255 KHNERFERNETED--KGSKRSIKWFTEFLQANQHDVTKFWSDISELVVKTLIVAEPHVLHAYRMC 317

  Fly   730 ---QNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVK-GPLIQA--VLNTAL 788
               |.......|||:.|||:|||..|.|||||||.:||..::..:|..|| |.|:.|  :||...
Mouse   318 RPGQPPGSESVCFEVLGFDILLDRKLKPWLLEINRAPSFGTDQKIDYDVKRGVLLNALKLLNIRT 382

  Fly   789 YQVPPKLNERQQADILEELNLTGPLCHDKRIFTTCLTAEEVRKHNQYTNRSIEFREEYVDTILDN 853
            ......| .:|:|:....|....|:   :|:.......|:.|  :|...|..|.:|..:
Mouse   383 SDKRKNL-AKQKAEAQRRLYGQNPV---RRLSPGSSDWEQQR--HQLERRKEELKERLL------ 435

  Fly   854 LLPDDVRCLIVAED-ELARCQPLERIFPTAGTHVYLRYVENARYYNRLLDAWETKYAKNREMGIA 917
                .||..:..|: |........||:|.....:.      .:|...|..|::|
Mouse   436 ----QVRKQVSQEEHENRHMGNYRRIYPPEDKALL------EKYEGLLAVAFQT----------- 479

  Fly   918 LLSRYCRDKYHLQVSDAAMEKEPNVALTEIDMLHVRKDEVLDGATTLAILKPVVQEGCEV----- 977
                      .|....|:.::|.|..|.:     :|::::||           :.|.||:
Mouse   480 ----------FLSGRAASFQREMNNPLKK-----MREEDLLD-----------LLEQCEIDDEKL 518

  Fly   978 --------APIPDACI 985
                    .|.|..|:
Mouse   519 MGKTGRVRGPKPLCCM 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	108/309 (35%)
Ttll7	NP_001289886.1	TTL	91..376	CDD:281171	105/291 (36%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q6ZT98	388..450		16/77 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..570
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	658..688

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920