Protein Alignment TTLL4B and Ttll4

DIOPT Version :9

• Sequence 1: NP_001260010.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_001074653.1
• Gene: Ttll4 / 690512
• RGDID: 1594742
• Length: 1198
• Species: Rattus norvegicus
• Alignment Length: 971
• Identity: 323/971 - (33%)
• Similarity: 476/971 - (49%)
• Gaps: 171/971 - (17%)

  Fly    78 PASSHHLQPH--LAAPNRNHGRIVQSSTPQHRSSAGGGSAAGATA---------------SDSVS 125
            |.:|....|:  |||...|..|       :..|||..|..|...:               |..|.
  Rat   173 PMASSPTDPYLSLAAAGENPSR-------KSLSSAISGKIASPLSSYKPMLNNNSFMRPNSTKVP 230

  Fly   126 ARYSPPGQKQRSPPSPRKRLTPEKVANLGGGG------GGSKVGAQRIIIRGTPPNS-------- 176
            ...:..|.|..|.|    ::.|....:.||.|      |..||           |.|
  Rat   231 LSQATDGLKPVSSP----KIQPVSWHHSGGTGDCVPQPGDHKV-----------PQSIATVLDDV 280

  Fly   177 STPKVAATPSNVPVVANSVLQSEPYKKVQMLLKRAREEAFAKHTAG-NSAANGNGPKRSAH-SPP 239
            :.|...:|||.:.:...||..|      |......|.||   |..| :...:.....:..| :..
  Rat   281 TAPMAPSTPSTLNISTASVASS------QCSQSNFRREA---HPCGLDENTDSQSATKEVHFTEA 336

  Fly   240 IQ-------AKVPPSNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEEKSRLLTQNGLTKSA 297
            ::       .|:|...........:.||....::..|.....::..:..:|...|  .:|:...|
  Rat   337 VRKLAAKGFEKMPRQGYQFEQACFVNPSFQWGLLNRSRRWKPLMGQRFPQEDIGL--DSGILPGA 399

  Fly   298 A--TALETSLYA----SLYANAPQ----NSQPQFHS---PRISGGD----------------HVA 333
            :  ..|:::::.    |::..|..    |..|...|   |::.|.|                .||
  Rat   400 SDTLGLDSTVFCTKRISIHLLASHVHGLNPSPTCGSVVDPQLLGEDRAPVPPSSSLQPLGVAEVA 464

  Fly   334 SYVGVSLNKG-AGHDNDRKHEDDPCAAIDDINYYD-------DSDSEEEYVGTPFFLE-----ED 385
            :.:. |::.| .|.:.:...:.:.|:...|.:..|       ..|||:| :|..  ||     ::
  Rat   465 TRLS-SVHLGQPGKEPEEAKDLNSCSTKGDCSPTDLRPKQLEPEDSEDE-LGDG--LEDSCSHDE 525

  Fly   386 NTETRQSKHTRLLPQKTPSKESV-----RTTDSEASVYFRPEAILSP----SLFPHVPPYLNFTS 441
            |.|.........|...:|| |||     ...|..:......|.::.|    ||||:|.|.:.|.:
  Rat   526 NEEEEGDSECSSLSVVSPS-ESVAIISRNCVDLMSKSISNHEKVVRPALIYSLFPNVSPTIYFGT 589

  Fly   442 HADKGPPMPAALHRVLKWKLSPVMPKIVKRVVLNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSH 506
            ..::...:|....|:|:||:|.|.|.|||:.:..|.|:|.|...||:..|..||||||||:||.|
  Rat   590 RDERVEKLPWEQRRLLRWKMSTVTPNIVKQTIGRSHFKISKRNDDWLGCWGHHMKSPGFRSIREH 654

  Fly   507 QKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNASKLTKWI 571
            ||.||.||||:|||||.:||::.....:||||||.|..:|:|:|.|.:.||:.|  .:|...|||
  Rat   655 QKLNHFPGSFQIGRKDRLWRNLSRMQSRFGKKEFSFFPQSFILPQDSKLLRKAW--ESSSRQKWI 717

  Fly   572 VKPPASARGTGIRIVNKWSQFPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKD 636
            |||||||||.||::::||||.||.|||:||:|:.:|.||:.:|||:|:||.:||.:|||||::.|
  Rat   718 VKPPASARGIGIQVIHKWSQLPKRRPLLVQRYLHKPYLISGSKFDLRIYVYVTSYDPLRIYLFSD 782

  Fly   637 GLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVN 701
            ||.||||.|||..:.:|..:.|||||||:||.:..|..|.|..|||||||.|::||:.|..:|||
  Rat   783 GLVRFASCKYSPSMKSLSNKFMHLTNYSVNKKNAEYQANADETACQGHKWALKALWNYLSQKGVN 847

  Fly   702 TKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLH 766
            :..:|..::::|:|.|:|.|..:..:.:..|...|:|.||||||::|||||.||:||:|||||||
  Rat   848 SDAIWEKIKDVVVKTIISSEPYVTNLLKLYVRRPYSCHELFGFDIMLDENLKPWVLEVNISPSLH 912

  Fly   767 SELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQADIL---------------------EELNLT 810
            |..|||:.:||.:|:.:||.|.:.:|      ...|||                     |:..:|
  Rat   913 SNSPLDISIKGQMIRDLLNLAGFVLP------NMEDILSSSSSPSSSSGSSTSLPSSPREKCQMT 971

  Fly   811 GPLCHDKRIFTTCLTAEEVRKHNQYTNRSIEFREEYVDTILDNLLPDDVRCLIVAEDELARCQPL 875
            ..  |        .||::::|....|.:..:  :::..::||.|.|||||.|:..|||.:|....
  Rat   972 PE--H--------FTAQKMKKAYYLTQKVPD--QDFYSSVLDVLTPDDVRVLVEMEDEFSRRGQF 1024

  Fly   876 ERIFPTAGTHVYLRYVENARYYNRLLDAWETKYAKNREMGIALLSRYCRDKYHLQ-VSDAA 935
            |||||:..:..|||:.|..||:|.|...||.||..|:..|:.||..:|...:|.. |||:|
  Rat  1025 ERIFPSRISSRYLRFFEQPRYFNILTTQWEQKYHGNKLKGVDLLRNWCYKGFHTGIVSDSA 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	153/294 (52%)
Ttll4	XP_001074653.1	TTL	652..944	CDD:397308	154/299 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340496
Domainoid	1	1.000	340	1.000	Domainoid score	I1059
eggNOG	1	0.900	-	-		E1_KOG2156
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	1	1.000	-	-		FOG0006381
OrthoInspector	1	1.000	-	-		otm45378
orthoMCL	1	0.900	-	-		OOG6_101354
Panther	1	1.100	-	-	O	PTHR12241
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4643
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.710