Protein Alignment TTLL4B and ttll6

DIOPT Version :9

• Sequence 1: NP_001260010.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_001098994.1
• Gene: ttll6 / 564075
• ZFINID: ZDB-GENE-080107-1
• Length: 778
• Species: Danio rerio
• Alignment Length: 552
• Identity: 167/552 - (30%)
• Similarity: 252/552 - (45%)
• Gaps: 92/552 - (16%)

  Fly   441 SHADKGP---PMPAALHRVLKWK-----LSPVMPKIVKRVVLNSGFRIIKNTTDWMAVW-EKHMK 496
            :||:...   |:|.|..:..:.|     |:....:.|:|.....|.|......||...| :..:.
Zfish    30 THAEPSNTPIPLPVANKKKKRKKKLWINLTNCKYESVRRAARRYGIREAAEGEDWTLYWTDCSVS 94

  Fly   497 SPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVWP 561
            ......::.:||.||.||...|.|||.:.|:: |.|.|...||:....:::.:|.|.... |.:.
Zfish    95 LDRVMDMKRYQKINHFPGMNEICRKDLLARNM-NRMLKLFPKEYNIFPRTWCLPADYSDF-QAYT 157

  Fly   562 KNASKLTKWIVKPPASARGTGIRIVNKWSQFPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSI 626
            : |.|...:|.||.:..:|.||.:............::.|.|:.:|.:|:..|||:|:||::||.
Zfish   158 R-AKKHKTFICKPDSGCQGRGIYLTKSSKDIRPGEHMICQVYMSKPFIIDGFKFDLRIYVLVTSC 221

  Fly   627 NPLRIYMYKDGLARFASVKYSS-ELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQGHKWTLQS 690
            :|.|::||.:||.||.:..|:. .:|||::.|||||||:|||.|:|:.::||    .|.|..|.|
Zfish   222 DPFRVFMYDEGLVRFCTTHYTEPTVSNLEDVCMHLTNYAINKHSENFVRDED----TGSKRKLSS 282

  Fly   691 LWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYR---QNVNFRYNCFELFGFDVLLDENL 752
            ....:|:...:|::||..:.:.:||.::|....|...|:   .|......|||:.|||||||..|
Zfish   283 FKKHMEDMSYDTEKLWTDIEDAIIKTLISAHPILKHNYQTCFPNHASGSACFEILGFDVLLDRRL 347

  Fly   753 VPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQADILEELNLTGPLCHDK 817
            .|||||:|.|||..::..||..||..|        ||            |.|..:||..  |..:
Zfish   348 KPWLLEVNHSPSFTTDSRLDREVKDSL--------LY------------DTLVLINLGA--CDRR 390

  Fly   818 RIFTTCLTAEEVR--KHNQYTNRSIEFREEYVDTILDNLLPDDVRCLIVAEDELARCQPLE---- 876
            :|     |.||.|  |.....|||.|.|.|            :.|....|..||  .|..|
Zfish   391 KI-----TEEEKRRVKERLQQNRSREARNE------------EPRQSQAASMEL--MQKYEAKHM 436

  Fly   877 ----RIFPTAGTHVYLRYVENARYYNRLLDAWETKYAKNREMGIALLSRYCRDKYHLQVSDAAME 937
                ||||..|...|.:|.:::   :.|..  ||..:|.||        .|..:   |:.:..::
Zfish   437 GGFRRIFPRDGGEKYEKYFQHS---SSLFQ--ETAASKARE--------ECARQ---QLQELRLK 485

  Fly   938 KEPNVALTEIDMLHVRKDEVLDGATTLAILKP 969
            :|..    |.|....||.: |.|.:....:||
Zfish   486 QEQK----ERDKKGSRKQD-LQGESAGEKVKP 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	106/298 (36%)
ttll6	NP_001098994.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43		3/12 (25%)
		TTL	99..379	CDD:281171	107/306 (35%)
		c-MTBD region. /evidence=ECO:0000250|UniProtKB:Q8N841	365..445		33/120 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	402..422		7/31 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	485..542		9/33 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	758..778

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920