Protein Alignment TTLL4B and ttll4

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_001417762.2
• Gene: ttll4 / 558702
• ZFINID: ZDB-GENE-070912-313
• Length: 1069
• Species: Danio rerio
• Alignment Length: 973
• Identity: 320/973 - (32%)
• Similarity: 471/973 - (48%)
• Gaps: 194/973 - (19%)

  Fly    62 KDKMVMCKKLAHHNHVPASSHHLQPHLAAPNRNHGRIVQSSTPQHRSSAGGGSAAGATASDSVSA 126
            :.:.|:.|.|.|.|..||:.|. |||.           :..:.:.:|...|..|.....|...:.
Zfish   102 RTQSVLSKSLPHINTTPAACHR-QPHW-----------KLESLRFKSGLLGKRAFSPQLSVCPAC 154

  Fly   127 RYSPPGQKQRS------PPSPRKRLTPEKVANLGGGGGGSKVGAQRIIIRGTPPNSSTPKVAATP 185
            ...|....||.      |.:.....|..|:.|...|           ::|  |||:..|
Zfish   155 PSPPKSSSQRGVIEKVMPTNQSSPWTSNKLRNNSNG-----------VVR--PPNAKMP------ 200

  Fly   186 SNVPVVANSVLQSEPYKKVQMLLKRAREEAFAKHTAGN--SAANG---NGPKRSAHSPPIQAKVP 245
                          .:.|.:|            |:..|  |:.||   .|.|..|..|| |..||
Zfish   201 --------------TFSKQEM------------HSPANVMSSCNGTFSRGLKVDAMKPP-QPSVP 238

  Fly   246 PSNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEEKSRLLTQNGL---------------TK 295
            ..::|            :.:::|  ||.: :...:|.||.::...|.|               ||
Zfish   239 LKDIS------------TDVILN--HGKA-VKDLRQFEKIKVDNANELDCCMGHGVNEAPQRVTK 288

  Fly   296 -------SAATALETSLYA---------------------------SLYANAPQNSQPQF----- 321
                   :|:..|:.:::|                           |.:|....||...|
Zfish   289 ISSEAEFNASAVLKPNVHARQRTLNGLSNVKRITVGAVPVCLNDEESRFAPMETNSALSFGIIAD 353

  Fly   322 --------------HSPRISGGD-------------------------HVASYVGVSLNKGAGHD 347
                          ..|.::|.|                         ..||.|| .||..||.|
Zfish   354 EKCPSDVVCIGGDCAIPEVTGHDISPQSPSVYTVTNQISAIQLTKEESCQASPVG-PLNGEAGDD 417

  Fly   348 NDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFFLEEDNTETRQSKHTRLLPQKTPSKESVRTTD 412
            |...........:|:....|..:.:        |.::|:.:......|..:...:..:|.: :.|
Zfish   418 NSEIQRQGMLLDVDEEELPDKLEDD--------FSDDDDFDDCDVSSTASMAASSNVEEPI-SPD 473

  Fly   413 SEASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVLKWKLSPVMPKIVKRVVLNSG 477
            .|..:..|  :.|.||||||:|..|.|::..::...:||...::||||::.|.|.:||..:..|.
Zfish   474 VEGDLVER--SALVPSLFPHMPSTLYFSTANERVELLPAEQMKLLKWKITTVTPNVVKNTIFRSH 536

  Fly   478 FRIIKNTTDWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGF 542
            |:..|.:.||:..|..|||||||:.||..||.||.||||:|||||.:||::.....:|||:||||
Zfish   537 FKATKKSHDWLGCWGHHMKSPGFKAIREFQKLNHFPGSFQIGRKDRLWRNLSKMQARFGKREFGF 601

  Fly   543 MQKSYIMPDDLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQFPKDRPLVVQKYIERP 607
            ..:|:|:|.|::.||:.|....|| .||||||||||||.||::::||||.|:.|||:||||:.:|
Zfish   602 FPRSFILPQDIKLLRKAWDDGGSK-QKWIVKPPASARGIGIQVIHKWSQMPRKRPLLVQKYLHKP 665

  Fly   608 LLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNY 672
            .||:.||||:|:||.:||.:||.||::.|||.||||.||||.:..|:.:.|||||||:||.:..|
Zfish   666 YLISGNKFDLRIYVYVTSYDPLCIYIFNDGLVRFASCKYSSSMKTLNNKFMHLTNYSVNKKNSEY 730

  Fly   673 AKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYN 737
            ..|.|..|||||||.|::||..|.::|:||..:|..::::|||.|::.:..:|.:.:.:|...|:
Zfish   731 QSNSDDKACQGHKWALKALWQYLGSQGINTTLIWEKIKDMVIKTIIASDPYVNSLVKMHVRSPYS 795

  Fly   738 CFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQAD 802
            |.||||||::|||||.||:||:||||||||..|||:.:||.:|:.:||.|.:.:|  |.:.....
Zfish   796 CHELFGFDIMLDENLKPWVLEVNISPSLHSNTPLDVSIKGQMIRDLLNLAGFVLP--LRDDFAPS 858

  Fly   803 ILEELNLTGPLCHDKR-IFTTCLTAEEVRKHNQYTNRSIEFREEYVDTILDNLLPDDVRCLIVAE 866
            .....:.|..||...| .:...::.:|..|...|.::... .:::..|:||.|.|||||.|..:|
Zfish   859 GSSASSSTSSLCGGVREKWRPDISPDEKVKRAFYLSQRFG-DQDFCATVLDVLTPDDVRVLAESE 922

  Fly   867 DELARCQPLERIFPTAGTHVYLRYVENARYYNRLLDAWETKYAKNREMGIALLSRYCRDKYHL 929
            |||:|....||:||:..:..|||:.|..||.|.||:.||.||..:|..||.||...|..:.||
Zfish   923 DELSRKGDFERVFPSHASSRYLRFFEQPRYLNILLNQWEQKYWLSRSKGINLLRDLCEKRVHL 985

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	155/293 (53%)
ttll4	NP_001417762.2	None