Protein Alignment TTLL4B and TTLL5

DIOPT Version :9

• Sequence 1: NP_001260010.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_001287520.1
• Gene: TTLL5 / 43015
• FlyBaseID: FBgn0051108
• Length: 917
• Species: Drosophila melanogaster
• Alignment Length: 903
• Identity: 231/903 - (25%)
• Similarity: 360/903 - (39%)
• Gaps: 279/903 - (30%)

  Fly   161 KVGAQR--IIIRGTPPNSSTPKVAATPSNVPVVANSVLQSEPYKKVQMLLKRAREEAFAKHTAGN 223
            |:|::.  ::.|....|....|..:..|:..|:.::....|  |.||...|.|.||..:...:..
  Fly    29 KLGSREAVLVFRTNILNPKIRKTLSEKSSAQVLTDTKDNEE--KPVQSPQKLAEEEPTSSEPSSK 91

  Fly   224 SAANGNGPKRSAHSPPIQAKVPPSNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEE----- 283
            .|.:|     |........|.|   ..|..:..|..|.|.|.::|.:..|....:.:.||
  Fly    92 EALSG-----STQQKIFLLKKP---QQCDKSDKLTFSSPFKKILNRYSSSDTSISSEGEEPANSS 148

  Fly   284 --KSRLL--TQNGLTKSAATALETSLYASLYANAPQNSQPQFHSPRISGGDHVASYVGVSLNKGA 344
              |||:|  :||.:....||.|...                      ||.:.:|
  Fly   149 ENKSRVLKTSQNAINIKLATDLSNE----------------------SGYESIA----------- 180

  Fly   345 GHDNDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFFLEEDNTETRQSKHTRLLPQKTPSKESVR 409
                       |...|        |::|        .:|||..||.:.
  Fly   181 -----------PAKTI--------SNTE--------VIEEDQEETSED----------------- 201

  Fly   410 TTDSEASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVLKWKLSPVMPKIVKRVV- 473
              |:|.                              |..|||:..:: .:|......|:::::.
  Fly   202 --DAEC------------------------------GINMPASKLKI-TYKFHQTETKLLRKLFN 233

  Fly   474 ---------LNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIY 529
                     .|:.|.::     |..|   |||....|.:..:|:.||.|.|:.:.|||.::::|.
  Fly   234 VHGLTEVQGENNNFNLL-----WTGV---HMKLDIVRNLAPYQRVNHFPRSYEMTRKDRLYKNIE 290

  Fly   530 NNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQFPK 594
            ......|.|.|..:.:::::|  :||...|...|..: ..|||||.||:||.||.|||...|.|:
  Fly   291 RMQHLRGMKHFDIVPQTFVLP--IESRDLVVAHNKHR-GPWIVKPAASSRGRGIFIVNSPDQIPQ 352

  Fly   595 DRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMH 659
            |...||.|||..||.|:.:|.|:|:||::||.:||.||:|::|:.|.|:|||.....||...|||
  Fly   353 DEQAVVSKYIVDPLCIDGHKCDLRVYVLVTSFDPLIIYLYEEGIVRLATVKYDRHADNLWNPCMH 417

  Fly   660 LTNYSINKFSQNY-----AKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVS 719
            |.||||||:..:|     |::||.    ||||||.:|...|:.:..:|::|...:.:|:||.:::
  Fly   418 LCNYSINKYHSDYIRSSDAQDEDV----GHKWTLSALLRHLKLQSCDTRQLMLNIEDLIIKAVLA 478

  Fly   720 -GESGLN--RMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQ 781
             .:|.::  ||:..|.|   |||||:|||:|:|..|.|||||||:|||:..:.|||..||..|:
  Fly   479 CAQSIISACRMFVPNGN---NCFELYGFDILIDNALKPWLLEINLSPSMGVDSPLDTKVKSCLM- 539

  Fly   782 AVLNTALYQVPPKLNERQQADILEELNLTGPLCHDKRIFTTCL----TAEEVRKHNQYTNRSIEF 842
                               ||:|                 ||:    .:.|::.|  |..:...|
  Fly   540 -------------------ADLL-----------------TCVGIPAYSPEMKSH--YDQKWSRF 566

  Fly   843 REEYVDTILD--------------------NLLPDDVRCLIVAEDELARCQPLERIFPTAGT-HV 886
            |......|..                    ||..::.|.|..|..:.:|.....|||||..: ..
  Fly   567 RSSSCQRIATFPSTSQKTKKSKKKGAAINLNLTGEEQRILRNARLQYSRRGGFVRIFPTDDSMQR 631

  Fly   887 YLRYVENA---------------------RYYNRLLDAWETKYAK--------NREMGIALLSRY 922
            |..::::|                     ..||::|.  :..|:|        |.|     ..|.
  Fly   632 YGNFLDSANGIPISTPNVQSQTFQTPIIQHNYNQMLH--QNLYSKDGRQKQDDNNE-----ADRI 689

  Fly   923 CRDKYHLQV-SDAAMEKEPNVALTEIDMLHVRKDEVLDGATTLAILKPVVQEGCEVAP 979
            .:.:..|:. |:....|:|.|...|::...:||           |:...:..|.|:.|
  Fly   690 WQYERALETDSEIPFVKKPTVEKCEVEGRRLRK-----------IMLKKISNGSELTP 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	121/302 (40%)
TTLL5	NP_001287520.1	TTL	266..549	CDD:281171	126/329 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450536
Domainoid	1	1.000	75	1.000	Domainoid score	I2480
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101354
Panther	1	1.100	-	-	P	PTHR12241
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850