Protein Alignment TTLL4B and Ttll3

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_038963762.1
• Gene: Ttll3 / 362415
• RGDID: 1311255
• Length: 1031
• Species: Rattus norvegicus
• Alignment Length: 864
• Identity: 188/864 - (21%)
• Similarity: 310/864 - (35%)
• Gaps: 300/864 - (34%)

  Fly    78 PASSHHLQPHLAAPNRNHGRIVQSSTP-QHRSSAGGGSAAGA---------------TASDSVSA 126
            |||:   :|.:|....:.|..  |..| :|.|||......||               |..:.:..
  Rat    68 PASA---RPEVARSGNSQGDC--SPLPARHLSSARERFVPGALDTVNPEPACSLVPPTLDEPLPD 127

  Fly   127 RYSPPGQKQRSPPSPRKRLTPEKV----ANLGGGGGGSKVGAQRIIIRGTPPNSSTPKVAATPSN 187
            ...|||.:.::.|.|   |||.::    |.:.|.|.........::.||.        ...||.:
  Rat   128 APPPPGGEAQNGPPP---LTPYRLQTEAAKVEGMGTLECTRDSLLLWRGF--------TKGTPHH 181

  Fly   188 VPVVANSVLQSE---PYKKVQMLLKR-------AREEAFAKHTAGNSAANGNGPKRSAHSPPIQA 242
            :..:.|:.:..|   ..||:.|:..|       .|:..:.:             |:..|
  Rat   182 MGRLRNAKIHVERAVKQKKIFMIHGRYPVIRCLLRQRGWVE-------------KKMVH------ 227

  Fly   243 KVPPSNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEEKSRLLTQNGLTKSAATALETSL-- 305
              ||.        |:.| ||||.:.:|..|.|..:..:.||:|.:..::.|..     |:..|
  Rat   228 --PPG--------TILP-PPSKDLDSSMLGDSDATEDEDEEESEMFRESQLLD-----LDGFLEF 276

  Fly   306 -----YASLYANAPQNSQPQF---------------------HSPRISGGDHVASYVGVSLNKGA 344
                 ..:|.:...:|..|..                     |..|...   ..:.||:.||
  Rat   277 DDLDGIHALMSRMVRNETPYLIWTTRRDVLDCRFLSKDQMINHYARAGS---FTTKVGLCLN--- 335

  Fly   345 GHDNDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFF-------LEEDN---------TETR--- 390
                           :.::.::|::|::.      ||       .|:|.         |..|
  Rat   336 ---------------LRNLPWFDEADADS------FFPRCYRLGAEDDKKAFIEDFWLTAARNVL 379

  Fly   391 ---------------QSKHTRLLPQKTPSKESVR--TTDSEASVYFRPEAILSPSLFPHVPPYLN 438
                           |::....|....|.|:..:  |..|:    |..||:.:      ...:|:
  Rat   380 KLVVKLEGRSQSIPIQAREEEALEDTQPKKQEKKPVTVSSD----FVDEALSA------CEEHLS 434

  Fly   439 FTSH--ADKGPPMPAALHRVLKWKLSPVMPKIVKRVVLNSGFRIIKNTTDWMAVWEKHMKSPGFR 501
            ..:|  .||.|..|.        .|||                     .||....:::     ::
  Rat   435 NIAHKDIDKDPNAPL--------YLSP---------------------DDWSLFLQRY-----YQ 465

  Fly   502 TIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDD-LESLRQVWPKNAS 565
            .::.|              ...:..|.|:.     ..|..:::......:| |:.||.|.|:...
  Rat   466 IVQPH--------------SPQVLLSPYSQ-----GAELRYLEVQVQRCEDILQQLRAVVPQIDM 511

  Fly   566 KLTK--WIVKPPASARGTGI----------RIVNKWSQFPKDRPLVVQKYIERPLLINDNKFDMR 618
            :..:  |||||.|.:||.||          ::|:......||...:|||||||||||...|||:|
  Rat   512 EGDRNIWIVKPGAKSRGRGITCMDHLDEMLKLVDCNPMLMKDGKWIVQKYIERPLLIFGTKFDLR 576

  Fly   619 LYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQG 683
            .:.::|..|||.::.|:|...||::..:|  |.||| ..:||.|.||.:..:        .:|..
  Rat   577 QWFLVTDWNPLTVWFYRDSYIRFSTQPFS--LKNLD-NSVHLCNNSIQRHLE--------ASCHR 630

  Fly   684 H-------KWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFEL 741
            |       .|:.|...:.|:.  |:..:.|:|   :::.|:.:......:..:.||..|...|||
  Rat   631 HPMLPPDNMWSSQRFQAHLQE--VDAPKAWST---VIVPGMKAAVIHALQTSQDNVQCRKASFEL 690

  Fly   742 FGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQADILEE 806
            :|.|.:..|:..|||:|||.||::           .|      :||   |..:|....|||.|.
  Rat   691 YGADFVFGEDFQPWLIEINASPTM-----------AP------STA---VTARLCAGVQADTLR- 734

  Fly   807 LNLTGPLCHDKRIFTTCLT 825
                  :..|:|:..:|.|
  Rat   735 ------VVIDRRMDRSCDT 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	87/313 (28%)
Ttll3	XP_038963762.1	TTL	439..743	CDD:397308	102/399 (26%)