Protein Alignment TTLL4B and TTLL12

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_610325.1
• Gene: TTLL12 / 35732
• FlyBaseID: FBgn0033225
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 615
• Identity: 139/615 - (22%)
• Similarity: 228/615 - (37%)
• Gaps: 168/615 - (27%)

  Fly   231 PKRSAHSP-PIQAKVPPSNMSCPSTQTLKPSPPSKIVVNSFHGSSML--STQQQEEKSRLLTQNG 292
            |.....|| |:.|      :.....|.:|.|.|..|.:.....:..|  :.||.||..:|..:
  Fly    61 PAEDDDSPNPVFA------LGVAREQGIKASDPQAIYLVDHAWTFRLNGARQQLEEYPQLAER-- 117

  Fly   293 LTKSAATALETSL-------------YASLYANAPQNSQPQFHSPRISGGDHVASYVGVSLNKGA 344
              .||.|.::..|             |...|:...:....:...|..    :|...||.::|
  Fly   118 --LSAITGVDLELKDRVDKILRRLWKYCHAYSIGSEGLSDEERQPIW----YVMDEVGSAVN--- 173

  Fly   345 GHDNDRKHEDDPCAAIDDINYYDDSDSEEEYVGTPFFLEEDNTETRQSKHTRLLP------QKTP 403
                   |.|||...:..:.|.                   ||:|..|.   |.|      .:..
  Fly   174 -------HSDDPNFRLVPLLYL-------------------NTQTTYSV---LFPIRDCDVGEAV 209

  Fly   404 SKESVRTTDSEASVYFRP-------EAILSPSLFPHVPPYLN-FTS-HA----DKGP--PMPAAL 453
            :::.|.....:|..  ||       :|.|:...|..|.|..: ||| |.    .||.  |:||
  Fly   210 TRDMVEHVAKDAPQ--RPALLLPWRDADLTGESFLQVEPRADYFTSGHIPETYPKGDTVPLPA-- 270

  Fly   454 HRVLKWKLSPVMP----KIVKRVVLNSGFRIIKNTTDWMAVWEKHM---------KSPGFRTIRS 505
                :.:..|:..    ::|:|.:.:|.|.::.|..:...:|..|.         :|||
  Fly   271 ----RSRCDPLKVYAEYEVVRRHLTSSEFILVNNADEADVLWLTHHFKNFEDFADRSPG------ 325

  Fly   506 HQKY-NHIPGSFRIGRKDTMWRSIYNNMKKFGKKEF---------GFMQKSYIMPDDLESLRQVW 560
              |: |..|..:.|..||.:  ||..  ::..|:..         .::..:|.:..:::.....:
  Fly   326 --KFINQFPFEYVITIKDLL--SIVG--RRAAKEHHDSLTLETFPAWLPTTYNLSTEVKEFAAYY 384

  Fly   561 PKNASK--LTKWIVKPPASARGTGIRIVNKWSQ---FPKDRPLVVQKYIERPLLINDN------K 614
            ...|:|  ...||:||...|||....|.:...|   .|...|.:.|||||||:|.:..      |
  Fly   385 QTRAAKGLDNHWIIKPWNLARGLDTHITDNIKQIVRLPATGPKIAQKYIERPVLFSRQEVEGSVK 449

  Fly   615 FDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMHLT--NYSINKFSQNYAKNED 677
            ||:|..::|.|:.||:.|:::....|||:..::  |.:.|:...|.|  ||. .:...::.|.:|
  Fly   450 FDIRYVILLKSVKPLKAYIHRKFFLRFANHPFT--LDHFDDYEKHYTVMNYQ-TEAQLHHVKCDD 511

  Fly   678 FNACQGHKWTLQ---SLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCF 739
            |...    |..|   :.||.||.:..:     ..|..|..........||....:...
  Fly   512 FLTL----WQEQYPDNDWSALEQQICS-----MLLEVLQCASQADPPCGLAPCAQSRA------- 560

  Fly   740 ELFGFDVLL------DENLVPWLLEINISP 763
             |:..|::|      ::.:.|.|||||.:|
  Fly   561 -LYAADIMLRWKDDKEKLMEPQLLEINWTP 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	72/292 (25%)
TTLL12	NP_610325.1	CPSase_L_D2	328..613	CDD:473076	71/286 (25%)