Protein Alignment TTLL4B and Ttll8

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_056840443.1
• Gene: Ttll8 / 315214
• RGDID: 1306462
• Length: 927
• Species: Rattus norvegicus
• Alignment Length: 792
• Identity: 168/792 - (21%)
• Similarity: 290/792 - (36%)
• Gaps: 212/792 - (26%)

  Fly   129 SPPGQKQRSPPSPRKRLTPEKVANLGGG---------------GGGSKVGA----QRIIIRGTPP 174
            |..|...|..|.|..|..|.:..:...|               ...|:|.:    |||.:..:||
  Rat     4 SVQGLSPRPRPRPHPRPGPGRSLDRNTGLDLEPRFCVKASNSVRTASRVPSLRRCQRIPLSRSPP 68

  Fly   175 NSSTPKVAATPSNVPVV----ANSVLQSEPYKKVQMLLKRAREEAFAKHTAGNSAANGNGPKRSA 235
            .|..|....:|:  |.|    |...|:.:.:...| .:.:||..|.     ||....|...:|||
  Rat    69 QSLPPVRPRSPT--PRVGRRSARRKLRRQRHGSAQ-CIAQARPVAL-----GNRKTPGRSGRRSA 125

  Fly   236 HSPPIQAKVPP---SNMSCPSTQTLKPSPPSKIVVNSFHGSSMLSTQQQEEKSRLLTQNGLTKSA 297
            .:.....:||.   ...:.....:::.....|:       :|.||....:|:::|  :.|:.:..
  Rat   126 AAARAVGRVPAGAGGQRNQLREASMENGERKKL-------TSTLSDGDHKEENKL--KQGIPQDL 181

  Fly   298 ATALETSLYA----------------SLYANAP------------QNSQPQFHSP--RISGGDHV 332
            :::.:...|.                |:|.:.|            :.....|..|  .:.|.|..
  Rat   182 SSSPKLDRYKIARQLTEKAIKEKKIFSIYGHYPVIRATLRRKGWVEKKFNFFPKPLQNVEGEDKS 246

  Fly   333 ASYVGVSLNKGAGHDNDRKHEDDPCAAIDDI---------------------------------- 363
            |              ..:::::......|||
  Rat   247 A--------------ETKENQEIALERFDDIHDVMSRLVKNEIPYLLWTIKRDVVDYHSLTCDQM 297

  Fly   364 -NYYDDSDSEEEYVGTPFFLEEDNTETRQSKHTRLLP---QKTPSKESVR----TTDSEASVY-- 418
             |:|..:.|....:|.             ..:.|.||   |..|:....|    .|:||...:
  Rat   298 LNHYGKTASFTTKIGL-------------CLNMRSLPWYVQANPNTFFPRCYGLCTESEKQEFLD 349

  Fly   419 -FRPEAILSPSLFPHVPPYLNFTS---------HADKGPPMPAALHRVLKWKLSPVMPKI----V 469
             ||  ..::.|:...|..:.|:.:         .|..|.|.|         |..|..|.:    :
  Rat   350 DFR--RTVAASILKWVVHHQNYCNRAKGKSKKEEAKNGDPSP---------KKDPDNPDLKLPSL 403

  Fly   470 KRVVLNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRI---GRKDTMWRSIYNN 531
            ...|:::..::.:.....:...:..:.......: |.:::|.:...:.:   |.     .||.::
  Rat   404 SGQVVDTACKVCQAYLGQLEHEDIDLSDASAEAL-SEEEWNDLTQQYYLLVHGN-----ASITDS 462

  Fly   532 MKKFGKKEFGFMQKSYIMPD-DLESLRQVWPKNASKLTKWIVKPPASARGTGI----RIVN---- 587
            ...|.:.:....:.|.:.|. :::.:|.:          ||:||.|.:||..|    |:.|
  Rat   463 RSYFAQCQALLSKISSVNPQTEIDGIRNI----------WIIKPAAKSRGRDIVCMDRVENILDL 517

  Fly   588 --KWSQFPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSEL 650
              ..||..||...|||||||.|:||.|.|||:|.:.::|..|||.|:.||:...||::.::|  |
  Rat   518 VATDSQTTKDNKWVVQKYIETPMLIYDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFS--L 580

  Fly   651 SNLDERCMHLTNYSINKFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIK 715
            ..||. .:||.|.||.:..:|..:......|. :.||.......|:.||..     .|..:::..
  Rat   581 DKLDS-AIHLCNNSIQRRLKNDKERSPLLPCH-NMWTSTRFQEYLQKRGRG-----GTWGSIIYP 638

  Fly   716 GIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLHSELP----LDLHVK 776
            .:....:...|:.:.:|..|.|.|||:|.|.:|..:..|||:|||.||::|...|    |...|:
  Rat   639 SMKRAVTNAMRVAQDHVEARKNSFELYGADFILGRDFKPWLIEINSSPTMHPSTPVTAQLCAQVQ 703

  Fly   777 GPLIQAVLNTAL 788
            ...|:.|::..|
  Rat   704 EDTIKVVVDRKL 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	89/303 (29%)
Ttll8	XP_056840443.1	TTL	<489..711	CDD:397308	79/240 (33%)