DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TTLL4B and Ttll2

DIOPT Version :9

Sequence 1:	NP_001260010.1	Gene:	TTLL4B / 33609	FlyBaseID:	FBgn0031574	Length:	989	Species:	Drosophila melanogaster
Sequence 2:	XP_006227981.1	Gene:	Ttll2 / 292311	RGDID:	1305200	Length:	541	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	130/382 - (34%)
Similarity:	192/382 - (50%)	Gaps:	48/382 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   450 PAALHRVLKWKLSPVMPKIVKRVVLNSGF----RIIKNTTDWMAVWEKHMKSPGFR-----TIRS 505
            |.|..:.|.:::....|.:|:.|:|..|:    ...::..||...|    :|..||     .|:.
  Rat    38 PGAALKPLVFRVDESTPGVVQSVLLERGWDKFDEQCQDVEDWNLYW----RSSSFRMAEYVNIKP 98

  Fly   506 HQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNASKL-TK 569
            .|:.||.||:..:.|||.:.:.:.:..:.:|:..:.|...::|||.|.......:.|....| ||
  Rat    99 WQRLNHHPGTTSLTRKDCLAKHLAHMRRLYGESIYEFTPLTFIMPSDYTKFVAKYFKEKQDLGTK 163

  Fly   570 ---WIVKPPASARGTGIRIVNKWSQFPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRI 631
               ||.||...::|.||.|.:...........||||||..|||:...|.|:|:||.:|...||.|
  Rat   164 PSYWICKPAKLSQGRGIIIFSDIRDLMFKDAYVVQKYICNPLLVGRYKCDLRIYVCVTGFKPLTI 228

  Fly   632 YMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQGHKWTLQSLWSCLE 696
            |||::||.|||:.|:  :||||::...||||.||||...:|.|.::. ..||.||||...:|.|.
  Rat   229 YMYQEGLVRFATEKF--DLSNLEDYYSHLTNSSINKLGASYEKIKEV-VGQGCKWTLSRFFSYLR 290

  Fly   697 NRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINI 761
            |..|:...|...:.::||..:::        ...:|....|||||||||:|:|:||.|||||:|.
  Rat   291 NWDVDDLLLRRKINHMVILTVLA--------MAPSVPVANNCFELFGFDILIDDNLKPWLLEVNY 347

  Fly   762 SPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQADILEELNLTGPLCHDKR 818
            ||:|..|...|:.||..|:.                    ||:|.|.|.|....:|:
  Rat   348 SPALSLECSTDVSVKRSLVH--------------------DIIELLYLNGLRSEEKK 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	108/298 (36%)
Ttll2	XP_006227981.1	TTL	98..371	CDD:281171	110/303 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920