Protein Alignment TTLL4B and Ttll13

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_006540976.1
• Gene: Ttll13 / 269954
• MGIID: 1920845
• Length: 849
• Species: Mus musculus
• Alignment Length: 586
• Identity: 165/586 - (28%)
• Similarity: 257/586 - (43%)
• Gaps: 102/586 - (17%)

  Fly   361 DDINYYDDSDSEEEYV----GTPFFLEE-----DNTETRQSKHTRLLPQKTPSK--ESVRTTDSE 414
            |||   ::.:||||.|    .||...::     |..|........::.:|.|.|  .:..|.|.|
Mouse    14 DDI---EEEESEEECVREESTTPNSTQQALRKADYKEFENGVALSVVAKKIPKKILSATDTDDLE 75

  Fly   415 ASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVLKWKLS-PVMPKIVKRVVLNSGF 478
            .....|..        ...|..:|.|:...:...:|..:.......:. ||  ..|:|.....|.
Mouse    76 VGRRRRKR--------KRRPLAINLTNCKYESARVPGFMAGTQAGSVDLPV--STVRRAAQMCGL 130

  Fly   479 RIIKNTTDWMAVW-------EKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFG 536
            :.:....:|...|       |:.|....|      ||.||.||...|.|||.:.|:: |.|:|..
Mouse   131 KEVGEDEEWTVYWTDCSVSLERVMDMKRF------QKINHFPGMTEICRKDLLARNL-NRMQKLY 188

  Fly   537 KKEFGFMQKSYIMPDDLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQFPKDRPLVVQ 601
            ..|:....:::.:|.|.... |.:.:. .|...:|.||.:..:|.||.|.....:......::.|
Mouse   189 PTEYNIFPRTWCLPADYGDF-QAYGRQ-RKTRTYICKPDSGCQGRGIFITRTPKEIKPGEHMICQ 251

  Fly   602 KYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKY-SSELSNLDERCMHLTNYSI 665
            :||.:|.||:..|||||:||::||.:||||:||::||||||::.| ....:||:|.|||||||:|
Mouse   252 QYITKPFLIDGFKFDMRIYVLITSCDPLRIFMYEEGLARFATMPYVEPSHNNLEEVCMHLTNYAI 316

  Fly   666 NKFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQ 730
            ||.::|:.:::    ..|.|..|.:|.:.|.....:.:.||..:.:::||.|:|..|.|...||.
Mouse   317 NKHNENFVRDD----AVGSKRKLSTLNAWLREHSHDPQELWGDIEDIIIKTIISAHSVLRHNYRT 377

  Fly   731 NVNFRY------NCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALY 789
            ... :|      .|||:.|||:|||..|.|||||:|.|||..::..||..||..|:...:|..
Mouse   378 CFP-QYLCGGTCACFEILGFDILLDHKLKPWLLEVNHSPSFTTDSRLDREVKDALLCDAMNLV-- 439

  Fly   790 QVPPKLNERQQADILEELNLTGPLCHDK-----RIFTTCLTAEEVRKHN-QYTNRSIEFREEYVD 848
                .|....:..::||         ||     |:|.......|.|:.. :.:..::..:|.|.|
Mouse   440 ----NLRGCDKKKVIEE---------DKRRVKERLFPCHQQPRETRREQFELSQAAMHDQERYED 491

  Fly   849 TILDNLLPDDVRCLIVAEDELARCQPLERIFPTAGTHVYLRYVE-NARYYNRLLDAWETKYAKNR 912
            :.|..                     ..||:|...:..|..:.: |...:.      ||..:|.|
Mouse   492 SHLGG---------------------YRRIYPGPDSEKYAPFFKHNGSLFQ------ETAASKAR 529

  Fly   913 E 913
            |
Mouse   530 E 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	110/300 (37%)
Ttll13	XP_006540976.1	TTL	154..439	CDD:397308	111/298 (37%)