Protein Alignment TTLL4B and ttll-11

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_741471.2
• Gene: ttll-11 / 177677
• WormBaseID: WBGene00019230
• Length: 707
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 165/668 - (24%)
• Similarity: 302/668 - (45%)
• Gaps: 121/668 - (18%)

  Fly   339 SLNKGAGHDNDRKHEDDPCAAIDDINYYDDSDSEEEY-----VGTPFFLEEDNTETRQ-SKHTRL 397
            |::....|..|.   ..|..||..:.:|::...:::.     :....:.|::..:..| |.:.|:
 Worm    17 SISTSKVHPTDL---STPSYAIKPVEFYEEPLKDDQLFYKVALAKKEYREKEKDKKEQLSSNRRV 78

  Fly   398 LPQKTPSKESV---RTTDSEASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVLKW 459
            ..|..|:|..:   |::...:.:..||.:.:|.|.|      :...:.|.:...:..:..:..::
 Worm    79 SLQVEPNKLPIPLTRSSSLSSIMENRPPSGISNSSF------IRSRNTASRRFTIDTSRAKSNQY 137

  Fly   460 KLSPVMPKIVKRVVLNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSHQ-KYNHIPGSFRIGRKDT 523
            .:|....||  .::.....|..|...|  ..|...:.|...:.:.|.| :.|..||...:.:|.:
 Worm   138 VVSLCSKKI--GIIEYPDGRSDKQPCD--VYWHNVVLSDMNKIVTSPQSRVNKFPGMTELAKKIS 198

  Fly   524 MWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNAS--KLTKW-IVKPPASARGTGIRI 585
            :..|| ::|:|....|:.|...|:.:|..|......:.|..:  |...| ||||...|:||||.:
 Worm   199 LTHSI-SSMQKLFPDEYAFYPNSWFLPAHLADFHAFYRKAQALGKTEMWFIVKPDEGAQGTGIYL 262

  Fly   586 VNKWSQFPK-DRPLVVQKYIERPLLINDN-KFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSS 648
            :|..:|... |:..:||:|:..|||:||. |||.|:|.|:.|||||.||:.::|:|||.:.||..
 Worm   263 INSPNQIRNVDQRQLVQEYVADPLLMNDKLKFDFRVYGVIKSINPLSIYVAREGMARFCTEKYEK 327

  Fly   649 -ELSNLDERCMHLTNYSINKFSQNYAKNEDF-NACQGHKWTLQSLWSCLENRGVNTKRLWATLRN 711
             :.||......||||||:||.::.|..:... :..:|.|..|.:::..||:|||.|||||..::.
 Worm   328 PDSSNFKNLYAHLTNYSLNKANEAYVHSNTLQDQTRGSKRLLSTVFHQLESRGVKTKRLWHDIKL 392

  Fly   712 LVIKGIVSGESGLNRMYRQNVNFRYN-----CFELFGFDVLLDENLVPWLLEINISPSLHSE--L 769
            :::|..::....:...|..:.   |:     ||::.||||::.|:..|.|||:|.:|||.::  :
 Worm   393 ILVKTTLAMLPEIMLHYEHHF---YDSTGPQCFQIMGFDVMIREDGTPILLEVNAAPSLTADHIV 454

  Fly   770 PLDLHVKGPLIQAVLNTALYQVPPKLNERQQADILEELNLTGPLCHDKRIFTTCLTAEEVRKHNQ 834
            |   |....|::.             .:|.::.:.|.:.:  ||..|..:....|..||
 Worm   455 P---HPGRTLLEG-------------GQRVRSIVDEVIKI--PLVRDTLLLVLGLMEEE------ 495

  Fly   835 YTNRSIEFREEYVDTILDNLLPDDVRCLIVAEDELARCQPLERIFPTA-GTHV-YLRYVENARYY 897
            |.|.|::...:.:         ||::.:     :..|...|..||||. |.|. :|.:::.|.|
 Worm   496 YQNNSLKGETKSL---------DDMQTI-----KQRRKPHLSEIFPTRYGAHSGHLLFLDKAMY- 545

  Fly   898 NRLLDAWETKYAKNREMGIALLSRYCRDKYHLQVSDAAMEKEPNVALTEIDMLHVRKDEVLDGAT 962
                                :..::.:.:.::.:::|.:::            .|||..::|
 Worm   546 --------------------IYMQFVQLRSNVNITNAGLKQ------------FVRKCNLID--- 575

  Fly   963 TLAILKPVVQEGCEVAPI 980
                :.|||....:|:.|
 Worm   576 ----IIPVVHVDAKVSEI 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	102/308 (33%)
ttll-11	NP_741471.2	CPSase_L_D2	183..451	CDD:473076	97/271 (36%)