Protein Alignment TTLL4B and TTLL8

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_024307940.1
• Gene: TTLL8 / 164714
• HGNCID: 34000
• Length: 776
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 90/353 - (25%)
• Similarity: 150/353 - (42%)
• Gaps: 80/353 - (22%)

  Fly   552 DLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQF----PKDRPL------VVQKYIER 606
            |::.||.:          ||:||.|.:||..|..:::..:.    ..|.||      |||||||.
Human   343 DIDGLRNI----------WIIKPAAKSRGRDIVCMDRVEEILELAAADHPLSRDNKWVVQKYIET 397

  Fly   607 PLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQN 671
            ||||.|.|||:|.:.::|..|||.|:.||:...||::.::|  |..||. .:||.|.::.|:.:|
Human   398 PLLICDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFS--LDKLDS-AIHLCNNAVQKYLKN 459

  Fly   672 YAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRY 736
            ........... :.||.......|:.:|...  :|.   :::...:....:...::.:.:|..|.
Human   460 DVGRSPLLPAH-NMWTSTRFQEYLQRQGRGA--VWG---SVIYPSMKKAIAHAMKVAQDHVEPRK 518

  Fly   737 NCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTA------------LY 789
            |.|||:|.|.:|..:..|||:|||.||::|...|:...:...:.:..:..|            |:
Human   519 NSFELYGADFVLGRDFRPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVAVDRSCDIGNFELLW 583

  Fly   790 QVPPKLNERQQADILEELNLTGPLCHDKRIFTTCLTAEEVRKHNQYTNRSIEFREEYVDTILDNL 854
            :.|          ::|....:|.        ..|:....||:..:                  .:
Human   584 RQP----------VVEPPPFSGS--------DLCVAGVSVRRARR------------------QV 612

  Fly   855 LPDDVRCLIVAEDELARCQPLERIFPTA 882
            ||   .|.:.|...|...|||:...|:|
Human   613 LP---VCNLKASASLLDAQPLKARGPSA 637

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	75/267 (28%)
TTLL8	XP_024307940.1	TTL	<348..574	CDD:397308	71/244 (29%)