Protein Alignment TTLL4B and TTLL11

DIOPT Version :9

• Sequence 1: NP_001260010.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_001132914.2
• Gene: TTLL11 / 158135
• HGNCID: 18113
• Length: 710
• Species: Homo sapiens
• Alignment Length: 619
• Identity: 173/619 - (27%)
• Similarity: 269/619 - (43%)
• Gaps: 136/619 - (21%)

  Fly   379 PFFLEEDNTETRQSKHTRLLPQKTPSKESVRTTDSEASVYFRPEAILSPSLFPHVPP------YL 437
            |...||.||:..|    |..|...|||               |:.:  ..|.||..|      ..
Human    70 PSAAEEGNTQVLQ----RPPPTLPPSK---------------PKPV--QGLCPHGKPRDKGRSCK 113

  Fly   438 NFTSH--ADKGPPMPAALH---------------RVLKWKLSPVMPKIVKRVVLNSGFRIIKNTT 485
            ..:.|  .:.|...|..:.               |.||||..|...::...:
Human   114 RSSGHGSGENGSQRPVTVDSSKARTSLDALKISIRQLKWKEFPFGRRLPCDI------------- 165

  Fly   486 DWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMP 550
                .|  |..|.....|.|.| .|..||...:.||.|:.|:: ..|:....:|:.|..:|:|:|
Human   166 ----YW--HGVSFHDNDIFSGQ-VNKFPGMTEMVRKITLSRAV-RTMQNLFPEEYNFYPRSWILP 222

  Fly   551 DDLE----SLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQFPKD---------RPLVVQK 602
            |:.:    .::.|...:.|....:||||....:|.||.::..    |.|         ||.|||:
Human   223 DEFQLFVAQVQMVKDDDPSWKPTFIVKPDGGCQGDGIYLIKD----PSDIRLAGTLQSRPAVVQE 283

  Fly   603 YIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSEL-SNLDERCMHLTNYSIN 666
            ||.:||||:..|||:||||:|.|::||.||:.||||:||.:..|.... .||....|||||||:|
Human   284 YICKPLLIDKLKFDIRLYVLLKSLDPLEIYIAKDGLSRFCTEPYQEPTPKNLHRIFMHLTNYSLN 348

  Fly   667 KFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQN 731
            ..|.|:..::  :|..|.|.|..|:...|.::||:.|::|:.:.::|||.:::....|...|:.:
Human   349 IHSGNFIHSD--SASTGSKRTFSSILCRLSSKGVDIKKVWSDIISVVIKTVIALTPELKVFYQSD 411

  Fly   732 VNFRY---NCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPP 793
            :....   .||::.|||:||.:||.|.|||:|.:||:..|     |      :..|:..:::..|
Human   412 IPTGRPGPTCFQILGFDILLMKNLKPILLEVNANPSMRIE-----H------EHELSPGVFENVP 465

  Fly   794 KL--NERQQADILEELNLTGPLCHDKRIFTTCLTAEEVRKHNQYTNRSIEFREEYVDTILDNLLP 856
            .|  .|.:.|.|.:.|.|..|| ..||           ...:|...:....:|:.:|..|.: .|
Human   466 SLVDEEVKVAVIRDTLRLMDPL-KKKR-----------ENQSQQLEKPFAGKEDALDGELTS-AP 517

  Fly   857 DDVRCLIVAEDEL-ARCQPLERIFPT-AGTHVYLRYVEN-ARYYNRLLDAWETKYAKNREMGIAL 918
            |   |....|..| :.|  |:::||. |....|||.|:. |..:.|.|....|  .|....|...
Human   518 D---CNANPEAHLPSIC--LKQVFPKYAKQFNYLRLVDRMANLFIRFLGIKGT--MKLGPTGFRT 575

  Fly   919 LSRYCRDKYHLQVSDAAMEKEPNVALTEIDMLHV 952
            ..|.|:      :|.:::      ::..:|:|::
Human   576 FIRSCK------LSSSSL------SMAAVDILYI 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	107/313 (34%)
TTLL11	NP_001132914.2	CPSase_L_D2	181..482	CDD:418439	108/319 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920