Protein Alignment TTLL4B and TTLL4B

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_061510801.1
• Gene: TTLL4B / 1280107
• VectorBaseID: AGAMI1_003091
• Length: 1312
• Species: Anopheles gambiae
• Alignment Length: 1031
• Identity: 413/1031 - (40%)
• Similarity: 567/1031 - (54%)
• Gaps: 192/1031 - (18%)

  Fly    16 TAAKENHSLTGRQNQQNHHNQGHQRSGKGIEILDFHESWLEEVELYKDKMVMCKKLAHHNHVPAS 80
            |:|.......|:|.|...:...:...|.|:...|.:.|.|:  .|.||:
Mosquito   192 TSASNAIGSNGQQQQAKENVAQNHLYGAGVNAKDVYMSELD--GLRKDR---------------- 238

  Fly    81 SHHLQPHLAAPNRNHGRIVQSSTPQHRSSAGGGSAAGATASDSVSARYSPPGQKQRSPPSPRKRL 145
                        ||.|..|.:........|....|..||.: ::..|.|....:.||...|::.:
Mosquito   239 ------------RNGGYYVPNELQLESRFARNLEANFATRA-TILERSSGRKLRARSESEPQEFM 290

  Fly   146 TPEKVAN-----LGGGGGGSKVGAQRII----------IRGTPPNSSTPKVAATPSNVPVVANSV 195
            ......|     .|||||.|.:..||..          :|.:..|:
Mosquito   291 YHSAHRNGAGFSAGGGGGSSLLAGQRTAGHHHHHHLHHLRHSRDNT------------------- 336

  Fly   196 LQSEPYKKVQMLLKRAR---------EEAFAKHTAGNSAANGNGPKRSAHSPPIQAKVPPSNMSC 251
                        |||.|         :|::|..|.....|.|:  :.|..|..:...||   :.|
Mosquito   337 ------------LKRTRDTISPTLEADESYAMLTGEEDTALGS--EASLSSSAVITCVP---VHC 384

  Fly   252 PSTQTLKPSPPSKIV-------VNSFH---GSSMLSTQQQEEK-SRLL--TQNGLTKSAATA--- 300
            |     |.|||||:|       |:..|   .|..::.|||..| :::|  |..|.:::|...
Mosquito   385 P-----KDSPPSKMVNAADEMDVSGDHVLSSSRTVADQQQRVKPAKILTGTATGQSRTAKVTVRA 444

  Fly   301 -------LETSLYASLYA------NAPQNSQPQFHSPRISG-GDHVASYVGVSLNKG-------- 343
                   |:..|.::|.:      :.|..::.:..||:... |...:|.:||..|.|
Mosquito   445 NRVGINRLKPKLASTLTSTGVVGTSVPGETKRKSASPQPQAKGTAGSSIIGVVHNTGSSSPTPSG 509

  Fly   344 -------------------------AGHDNDRKHEDDPCAAIDDINYYDDSDSE-----EEYVGT 378
                                     ||.|:|.   ||.|...|     ||.|.|     :|.:..
Mosquito   510 VSVGTSGGESVHTQDLDAETIDQSDAGDDDDL---DDECNGED-----DDLDDEIAISGDEVLDD 566

  Fly   379 PFFLEEDN-----------TETRQSKHTRLLPQKTPSKESVRTTDSEASVY--FRPEAILSPSLF 430
            .....|||           .::.....:..|..:.|:..|:      .||.  :.|...|:||||
Mosquito   567 SLTDSEDNYRSYLAAAYQKPKSHSGSPSPSLGNRAPAVTSI------GSVVGGYAPAGPLAPSLF 625

  Fly   431 PHVPPYLNFTSHADKGPPMPAALHRVLKWKLSPVMPKIVKRVVLNSGFRIIKNTTDWMAVWEKHM 495
            |:|||||.|.:|.:||||||.|:|:||||||:.:.|.:|::|:||||||::|.|.||:.:|.:||
Mosquito   626 PYVPPYLTFATHEEKGPPMPPAIHKVLKWKLTLITPIVVRKVLLNSGFRLLKKTNDWIGIWGRHM 690

  Fly   496 KSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPDDLESLRQVW 560
            ||..|:|:|.:||:||:||||:|||||.:||::...|.:.||||||||.::||:|.||:.|||:|
Mosquito   691 KSTLFKTLRPYQKFNHLPGSFQIGRKDRVWRNLQTQMNRHGKKEFGFMPRTYIIPQDLKMLRQMW 755

  Fly   561 PKNASKLTKWIVKPPASARGTGIRIVNKWSQFPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTS 625
            |:...:..|||:|||||||||||::||:|||.||.:||:||:|||||||||.:|||:||||::||
Mosquito   756 PRYNQRNCKWIIKPPASARGTGIKVVNRWSQIPKRKPLIVQRYIERPLLINGSKFDLRLYVLVTS 820

  Fly   626 INPLRIYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQGHKWTLQS 690
            :||||:||:.||||||||||||.:...|.:|.||||||||||.|.|||:|||.:||||||||::|
Mosquito   821 MNPLRVYMHTDGLARFASVKYSEKSETLSDRYMHLTNYSINKLSNNYAQNEDADACQGHKWTIKS 885

  Fly   691 LWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLVPW 755
            |||....:|:|..|||..|||||::.:::||..::.|.:.||..:|||:||||.|||||..||||
Mosquito   886 LWSYFAEQGINVDRLWGALRNLVLRTVLAGEGSIHAMSKVNVGSKYNCYELFGIDVLLDSELVPW 950

  Fly   756 LLEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQADILEELNLTGPLCHDKRIF 820
            |||:||||||||...|||.|||||::|:|||.:|||||::...:|.:||:|..|.||||.||||:
Mosquito   951 LLEVNISPSLHSASSLDLCVKGPLVKALLNTVMYQVPPRIPMAEQKEILKEQGLEGPLCFDKRIY 1015

  Fly   821 TTCLTAEEVRKHNQYTNRSIEFREEYVDTILDNLLPDDVRCLIVAEDELARCQPLERIFPTAGTH 885
            ||.|:..|..||.|:..:.:. ||:|::|||:.|.|||||||::.||||||..|||||.|...::
Mosquito  1016 TTGLSKTERLKHTQFIQKDMA-REDYLNTILEELTPDDVRCLLLTEDELARSAPLERILPAPNSY 1079

  Fly   886 VYLRYVENARYYNRLLDAWETKYAKNREMGIALLSRYCRDKYHLQVSDAAMEKEPN 941
            .|:.:.||.|||||||||||.:|..||..|||||...|..|.||||..:.::|:.|
Mosquito  1080 RYIGFTENPRYYNRLLDAWEHRYGHNRSEGIALLQSLCERKVHLQVPPSTLKKDCN 1135

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	186/293 (63%)
TTLL4B	XP_061510801.1	None