Protein Alignment TTLL4B and Ttll3

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: NP_598684.4
• Gene: Ttll3 / 101100
• MGIID: 2141418
• Length: 927
• Species: Mus musculus
• Alignment Length: 852
• Identity: 178/852 - (20%)
• Similarity: 303/852 - (35%)
• Gaps: 321/852 - (37%)

  Fly    78 PASSHHLQPHLAA---PNRNHGRIVQSSTP-QHRSSAGGGSAAGATASDSVSARYSPPGQKQRSP 138
            |||:   :|.:|:   ..|::     ||.| :|.|||...|..||..:      .:|...:...|
Mouse    68 PASA---KPEVASCGDSRRDY-----SSLPARHLSSARESSMPGALGT------VNPQPVRTLVP 118

  Fly   139 PSPRKRLTPEKVANLGGGGGGSKVGAQRIIIRGTPPNSST---PKVAATPSNVPVVANSVLQSE- 199
            |:..:.| |:.:                     .||:.|.   ..:...|:::..:.|:.:..|
Mouse   119 PTLDEPL-PDAL---------------------RPPDDSLLLWRGLTKGPNHMGRLRNAKIHVER 161

  Fly   200 --PYKKVQMLLKR-------AREEAFAKHTAGNSAANGNGPKRSAHSPPIQAKVPPSNMSCPSTQ 255
              ..||:.|:..|       .|:..:.:             |:..|        ||.
Mouse   162 AVKQKKIFMIHGRYPVIRCLLRQRGWVE-------------KKMVH--------PPG-------- 197

  Fly   256 TLKPSPPSKIVVNSFHGSSMLSTQQQEE------KSRLLTQNGLTKSAATALE----TSLYASLY 310
            |..|: |.|.:.:|..|.|..:..:.||      :|:||..:|.       ||    ..::| |.
Mouse   198 TALPA-PQKDLDSSMLGDSDATEDEDEEENEMFRESQLLDLDGF-------LEFDDLDGIHA-LM 253

  Fly   311 ANAPQNSQPQF---------------------HSPRISGGDHVASYVGVSLNKGAGHDNDRKHED 354
            :...:|..|..                     |..|...   ..:.||:.||
Mouse   254 SRMVRNETPYLIWTTRRDVLDCRFLSKDQMINHYARAGS---FTTKVGLCLN------------- 302

  Fly   355 DPCAAIDDINYYDDSDSEEEYVGTPFF---------------------------------LEEDN 386
                 :.::.::|::|::.      ||                                 |||.:
Mouse   303 -----LRNLPWFDEADADS------FFPRCYRLGAEDDKKAFIEDFWLTAARNVLKLVVKLEEKS 356

  Fly   387 TETRQSKHTRLLPQKT-PSKESVR--TTDSEASVYFRPEAILSPSLFPHVPPYLNFTSH--ADKG 446
            ............|:.| |.|:..:  |..|:    |..||:.:      ...:|:..:|  .||.
Mouse   357 QSISIQAREEEAPEDTQPKKQEKKLVTVSSD----FVDEALSA------CQEHLSSIAHKDIDKD 411

  Fly   447 PPMPAALHRVLKWKLSPVMPKIVKRVVLNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSHQKYNH 511
            |..|.        .|||                     .||....:::     ::.:....:..:
Mouse   412 PNSPL--------YLSP---------------------DDWSQFLQRY-----YQIVHEGAELRY 442

  Fly   512 IPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQKSYIMPD-DLESLRQVWPKNASKLTKWIVKPP 575
            :  ..::.|.:.:.:.:.|                 ::|. |:|..|.:          |||||.
Mouse   443 L--EVQVQRCEDILQQLQN-----------------VVPQLDMEGDRNI----------WIVKPG 478

  Fly   576 ASARGTGIRIVNKWSQ----------FPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLR 630
            |.:||.||..:|:..:          ..||...:|||||||||||...|||:|.:.::|..|||.
Mouse   479 AKSRGRGIMCMNRLDEMLKLVDCNPMLMKDGKWIVQKYIERPLLIFGTKFDLRQWFLVTDWNPLT 543

  Fly   631 IYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFNACQGH-------KWTL 688
            ::.|:|...||::..:|  |.||| ..:||.|.||.:..:        .:|..|       .|:.
Mouse   544 VWFYRDSYIRFSTQPFS--LKNLD-NSVHLCNNSIQRHLE--------ASCHRHPMLPPDNMWSS 597

  Fly   689 QSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLV 753
            |...:.|:.  |:..:.|:   ::::.|:.:......:..:.||..|...|||:|.|.:..|:..
Mouse   598 QRFQAHLQE--VDAPKAWS---SVIVPGMKAAVIHALQTSQDNVQCRKASFELYGADFVFGEDFQ 657

  Fly   754 PWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQADILEELNLTGPLCHDKR 818
            |||:|||.||::           .|      :||   |..:|....|||.|.       :..|:|
Mouse   658 PWLIEINASPTM-----------AP------STA---VTARLCAGVQADTLR-------VVIDRR 695

  Fly   819 IFTTCLT 825
            :..:|.|
Mouse   696 LDRSCDT 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	82/311 (26%)
Ttll3	NP_598684.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..113		17/58 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..227		12/49 (24%)
		TTL	423..698	CDD:397308	89/351 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	735..799
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	897..927