Protein Alignment TTLL4B and ttll3

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_002941012.2
• Gene: ttll3 / 100497708
• XenbaseID: XB-GENE-6035679
• Length: 749
• Species: Xenopus tropicalis
• Alignment Length: 654
• Identity: 146/654 - (22%)
• Similarity: 259/654 - (39%)
• Gaps: 148/654 - (22%)

  Fly   251 CPSTQTLKPSPPSK----IVVNSFHGSSMLSTQQ----QEEKSRLLTQNGLTKSAATALETSLYA 307
            |.|....|..|.:|    :.....|.|....|::    ..::::||.:..:.::....:
 Frog    18 CNSDTKTKKQPTAKDKHDVSPTKGHVSKKTHTKKINPDSLKQAKLLVEKAIQENKIFTI------ 76

  Fly   308 SLYANAPQNSQPQFHSPRISGGDHVASYVGVSLNKGAGHDNDRKHEDDPCAAIDDINYYDDSDSE 372
                        |.:.|.|..|.....:|..:.:| :.||    :.||| ..|.|:......:.:
 Frog    77 ------------QGYYPYIRSGLRSRGWVEKNFHK-SQHD----YFDDP-EGICDLTSRLLRNQD 123

  Fly   373 EEYVGTPFFLEEDNTETRQSKHTRLLPQKTPSKESVRTT---------------DSEASVYF--- 419
            ..:|..|.:   ::.::|..|:.:::...  ..:||.||               |::.:.:|
 Frog   124 PNFVWVPTY---NSLDSRLLKNDQIIINH--YSKSVFTTKVGLCLNLRNLHWFADADLNSFFPRC 183

  Fly   420 -------RPEAILSPSLFPHVPPYLNFTSHADKGPP--------MPAALHRVLKW--KLSPVMPK 467
                   ..||.:...........|...|...|..|        :.|||  :||:  |..|::..
 Frog   184 YRLGVKEEKEAFIEDFRLTAACSILKLVSREGKNMPNRRDVKKEITAAL--LLKYYKKAKPLITS 246

  Fly   468 IVKRVVLNSGFRIIK---NTT-----DWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTM 524
            :..::: .:..:..|   ||:     ||        |......|...:....:.|.::...|:.
 Frog   247 VPVQII-KTALKACKQYLNTSEHKDIDW--------KLGSTNAITEDEWKEFLHGYYQAIHKNI- 301

  Fly   525 WRSIYNNMKKFGKKEFGFMQK-SYIMPD-DLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVN 587
               |.|..:.:..:....:|| ..:.|. |::..|.:          |||||.||:||.||..::
 Frog   302 ---IINEAENYVSQCQDMLQKLKAVKPQLDIDGERNI----------WIVKPGASSRGRGITCID 353

  Fly   588 KWSQ----------FPKDRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFA 642
            ...:          |..|..|||||||||||||...|||:|.:.::|:.|||.|:.||:...||:
 Frog   354 YLEEALKYVDCDPLFINDDKLVVQKYIERPLLIYGTKFDVRQWFMVTNWNPLTIWYYKECYLRFS 418

  Fly   643 SVKYSSELSNLDERCMHLTNYSINKFSQNY--AKNEDFNACQGHKWTLQSLWSCLENRGVNTKRL 705
            |..:|  |.|| ...:||.|.::.|   ||  :::......:.:.|........|:..|..  ..
 Frog   419 SQPFS--LKNL-HSSIHLCNNAVQK---NYKISRSRHPRLPKENMWFKNQFQDYLQMTGAT--NA 475

  Fly   706 WATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLHSELP 770
            |   :.::..|:.:......:..:.....|.|.|:::|.|.:..||..|||:|||.:|    ::.
 Frog   476 W---KEIIEPGMKAAIIHTMQCSQDMEEGRKNSFQIYGADFMFGENFQPWLIEINANP----DMS 533

  Fly   771 LDLHVKGPLIQAVLNTALYQVPPKLNERQQAD--------ILEELNLTGPLCHDKRIFTTCLTAE 827
            |...|...|:..|....|..:   |:.:|.||        |.::..:..|||..|::.   :...
 Frog   534 LSTSVTSRLVVRVQEDILRLI---LDRKQDADAYVGVFELIYKQPVIKIPLCERKQLL---VKGN 592

  Fly   828 EVRK 831
            :::|
 Frog   593 QIKK 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	84/307 (27%)
ttll3	XP_002941012.2	TTL	286..552	CDD:397308	82/294 (28%)