Protein Alignment TTLL4B and LOC100490189

DIOPT Version :10

• Sequence 1: NP_722946.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_002933977.1
• Gene: LOC100490189 / 100490189
• XenbaseID: XB-GENE-29080059
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 835
• Identity: 180/835 - (21%)
• Similarity: 315/835 - (37%)
• Gaps: 228/835 - (27%)

  Fly   245 PPSNMSCPS-TQTLK-PSPPSKIVVNSFHGSSMLSTQQQE------EKSRLLTQNGLTKSAATAL 301
            |.....|.| |:..| |:...|..|:...|....:|.:::      ::::||.:..:.::....:
 Frog    12 PQQKKECNSDTKPNKQPTAKDKHDVSPTKGHVSKNTHRKKINPDSLKQAKLLVEKAIQENKIFTI 76

  Fly   302 ETSLYASLYANAPQNSQPQFHSPRISGGDHVASYVGVSLNKGAGHDNDRKHEDDPCAAIDDINYY 366
                              |.:.|.|..|..:..:|..:.:| :.||    :.||| ..|.|:...
 Frog    77 ------------------QGYYPYIRSGLRIRGWVEKNFHK-SQHD----YFDDP-EGICDLTSR 117

  Fly   367 DDSDSEEEYVGTPFFLEEDNTETRQSKHTRLLPQKTPSKESVRTT---------------DSEAS 416
            ...:.:..:|..|.:   :..::|..|:.:::  .....:||.||               |::.:
 Frog   118 LLRNQDPNFVWVPTY---NCLDSRLLKNDQII--MNHYSKSVFTTKVGLCLNLRNLHWFADADLN 177

  Fly   417 VYF----------RPEAILSPSLFPHVPPYLNFTSHADKGPP---------MPAALHRVLKWKLS 462
            .:|          ..:|.:...........|...|...|..|         .||.|.:..| |..
 Frog   178 SFFPRCYRLGVKEEKQAFIEDFRLTAACSILKLVSREGKNMPNRRDVKKESTPALLLKYNK-KAQ 241

  Fly   463 PVMPKIVKRVVLNSG--FRIIK----------NT-----TDWMAVWEKHMKSPGFRTIRSHQKYN 510
            |::..:      |:|  ..|||          ||     .||        |......|...:...
 Frog   242 PLITSV------NTGVPVHIIKTALKACKQYLNTLEHEDIDW--------KLGSTNAITEDEWKE 292

  Fly   511 HIPGSFRIGRKDTMWRSIYNNMKKFGKKEFGFMQK-SYIMPD-DLESLRQVWPKNASKLTKWIVK 573
            .:.|.:::..|:    .|.|..:.:..:....:|| ..:.|. |::..|.:          ||||
 Frog   293 FLDGYYQVIHKN----RIINEAENYVSQCQDILQKLKAVKPQLDIDGERNI----------WIVK 343

  Fly   574 PPASARGTGIRIVNKWSQFPK----DRP------LVVQKYIERPLLINDNKFDMRLYVVLTSINP 628
            |.||:||.||..::...:..|    |.|      |||||||||||||...|||:|.:.|:|:.||
 Frog   344 PGASSRGRGITCIDYLEEALKFVDCDPPFINHDKLVVQKYIERPLLIYGTKFDVRQWFVVTNWNP 408

  Fly   629 LRIYMYKDGLARFASVKYSSELSNLDERCMHLTNYSINKFSQNYAKNEDFN--ACQGHKWTLQSL 691
            |.|:.||:...||:|..:|  |.|| ...:||.|.:|.|   ||:.::..:  ..:.:.|.....
 Frog   409 LTIWYYKECYLRFSSQPFS--LKNL-HSSIHLCNNAIQK---NYSISQSRHPQLPKENMWFKNQF 467

  Fly   692 WSCLENRGVNTKRLWATLRNLVIKGIVSGESGLNRMYRQNVNFRYNCFELFGFDVLLDENLVPWL 756
            ...|:..|..  ..|   :.::..|:.:......:..:.....|.|.|:::|.|.:..||..|||
 Frog   468 QDYLQMTGAT--NAW---KEIIEPGMKAAIIHTMQCSQDMEEGRKNSFQIYGADFMFGENFQPWL 527

  Fly   757 LEINISPSLHSELPLDLHVKGPLIQAVLNTALYQVPPKLNERQQAD--------ILEELNLTGPL 813
            :|||.:|    ::.|...|...|:..|....|..:   |:.:|.||        |.::..:..||
 Frog   528 IEINANP----DMSLSTSVTSRLVARVQEDLLCLI---LDRKQHADADVGVFELIYKQPVIKIPL 585

  Fly   814 CHDKRIFTTCLTAEEVRKHNQYTNRSIEFREEYVDTILDNLLPDDVRCLI---VAEDELARCQPL 875
            |:.|::.   :...|::|                      |:.|:...:.   :|:||...|. |
 Frog   586 CYTKQLL---VKGNEIKK----------------------LMTDEKNQMFKGSIAKDERGPCL-L 624

  Fly   876 ERIFPTAG----------------THVYLRYVENARYYNRLLDAWETKYAKNREMGI--ALLSRY 922
            .|...||.                .|:.|..::..              .:.|:.|:  ..|.:.
 Frog   625 HRTKTTATWKEIKGGRETSPSKKVEHIILPTIKQG--------------LEKRKEGVNQYQLPKL 675

  Fly   923 CRDKYHLQVSDAAM--------EKEPNVALTEIDML-HVRKDEVLDGATTLAILK 968
            |..:..::..|.|.        :|.||:...::.:. |:.|.: ..|:.|.::.|
 Frog   676 CAHEKTIRRKDPARTKNEAFDHQKLPNINSGQLQVTGHLAKIQ-KPGSLTKSLYK 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_722946.1	TTL	504..798	CDD:397308	87/307 (28%)
LOC100490189	XP_002933977.1	TTL	290..555	CDD:397308	85/293 (29%)