Protein Alignment TTLL4B and ttll4

DIOPT Version :9

• Sequence 1: NP_001260010.1
• Gene: TTLL4B / 33609
• FlyBaseID: FBgn0031574
• Length: 989
• Species: Drosophila melanogaster
• Sequence 2: XP_002933990.3
• Gene: ttll4 / 100144652
• XenbaseID: XB-GENE-492394
• Length: 1103
• Species: Xenopus tropicalis
• Alignment Length: 1041
• Identity: 349/1041 - (33%)
• Similarity: 519/1041 - (49%)
• Gaps: 160/1041 - (15%)

  Fly    41 SGKGIEILDFHESWLEEVELYK-----------DKMVMCKKLAHHNHVPASSHH--LQPHLAAPN 92
            ||....:..||:.:..|:.|.:           :.:.:..|:|......||:.|  :.|.|..|
 Frog    92 SGSFHRLRSFHDPFDRELFLQRPVNDHTSFQRLESLWLRPKIAILRPYTASNKHPPITPTLKLP- 155

  Fly    93 RNHGRIVQSSTPQ-HRSSAGG----------GSAAGATASDS-----VSARYSPPGQKQRS--PP 139
              :..:..|...| |..||.|          ...|..|.|::     |:..:..|...:..  |.
 Frog   156 --YSAMATSLIDQRHLPSAAGEPHDISVRNPTRIATRTLSENPRPALVTNSFLRPSSAKVHFYPR 218

  Fly   140 SPRKRLTPEKVANLGGGG---GGSKVGAQ----RIIIRGTPPNSSTPKVAAT-PSNVPVV----- 191
            ..||.:.....:.|..|.   |.||...|    ..|..||  .|:..|.||| .:|..::
 Frog   219 LDRKPMNSTSSSPLHHGPKDIGQSKEETQPYCHSCIHPGT--TSTDHKGAATAKANDDILWKMVE 281

  Fly   192 ANSVLQSEPYKKVQMLLKRAREEAFAKHTAGNSAANGNGPKRSAHSPPIQAKVP-----PSNMSC 251
            .|:.:....|::.|:       ..|.|....    .|:..|.|...||::| :|     .:..||
 Frog   282 DNNAVDIMHYQEAQL-------TEFVKQLTD----KGDLLKTSHIVPPLEA-IPVICDDTAYTSC 334

  Fly   252 PST------------QTLKPSPPSKIVVN-----SFHGSSMLSTQQQEEKSRLLTQNGLTKSAAT 299
            ..:            .||.||....:.:|     :...::...|||.....:       .:|...
 Frog   335 KESVPFALNPAGHPQPTLLPSVSGDVCLNGNVDCTLANNANACTQQAAAHLK-------AQSPGA 392

  Fly   300 ALETSLYASLYANAPQNSQPQFHSPRISGGDHV--------ASYVG-VSLNKGAG-HDNDRKHE- 353
            :.|::...|||..||::   :.|.|.|  |::|        |:.:. :.||:.:| .|...:.|
 Frog   393 SCESNSCPSLYTLAPKS---ESHLPEI--GNNVQGVNITVMATQISTIHLNRTSGAKDTQAQPER 452

  Fly   354 -DD-----PCAAIDDI-----NYYDDSDSEEEYVGTPFFLEEDNTETRQSKHTRL-LPQKTPS-- 404
             ||     |...:|.|     :..|||:.|||        |||:.::...:.:.: :|....|
 Frog   453 IDDLPSPVPNQELDGIEEELPDDLDDSEVEEE--------EEDDEDSNVDQSSSIGIPSAASSFS 509

  Fly   405 -----KESVRTTDSEASVYFRPEAILSPSLFPHVPPYLNFTSHADKGPPMPAALHRVLKWKLSPV 464
                 .|||....||.....:|  ..|.||||:|.|.|.|.:..:|...:|.|..::||||:|.|
 Frog   510 NARQIDESVEQMSSEMDYTVKP--AFSKSLFPNVHPTLYFGTQEEKVELLPWAQRKLLKWKMSNV 572

  Fly   465 MPKIVKRVVLNSGFRIIKNTTDWMAVWEKHMKSPGFRTIRSHQKYNHIPGSFRIGRKDTMWRSIY 529
            .|.:||..:..|.||:.|...||:..|..||||..|:::|::||.||.||||:|||||.:||::.
 Frog   573 TPNVVKHTIARSHFRVTKKNQDWLGCWGHHMKSTAFKSLRAYQKLNHFPGSFQIGRKDRLWRNLS 637

  Fly   530 NNMKKFGKKEFGFMQKSYIMPDDLESLRQVWPKNASKLTKWIVKPPASARGTGIRIVNKWSQFPK 594
            .....:|||||.|..:|:::|.|::.|::.|.:..:: .||||||||||||.||::::||||.||
 Frog   638 KMQAHYGKKEFNFFPQSFVLPQDIKLLKKAWEEGGNR-QKWIVKPPASARGMGIQVIHKWSQLPK 701

  Fly   595 DRPLVVQKYIERPLLINDNKFDMRLYVVLTSINPLRIYMYKDGLARFASVKYSSELSNLDERCMH 659
            .|||:||:|:.:|.||:.:|||:|:||.:||.:||||||:.|||.||||.||||.:.:|..:.||
 Frog   702 KRPLLVQRYLHKPYLISGSKFDLRIYVYVTSFDPLRIYMFTDGLVRFASCKYSSSMKSLGNKFMH 766

  Fly   660 LTNYSINKFSQNYAKNEDFNACQGHKWTLQSLWSCLENRGVNTKRLWATLRNLVIKGIVSGESGL 724
            |||||:||.:.:|..|.|..|||||||.|::||:.|..:|.|:.|:|..::::|||.|::.:..:
 Frog   767 LTNYSVNKNNADYQANPDQTACQGHKWALKALWNYLNQKGFNSDRIWEKIKDIVIKTIIASDPYV 831

  Fly   725 NRMYRQNVNFRYNCFELFGFDVLLDENLVPWLLEINISPSLHSELPLDLHVKGPLIQAVLNTALY 789
            |...:..|...|.|.||||||::|||||.||:||:||||||||..|||:.:||.:|:.:||.|.:
 Frog   832 NSFVKMYVQSPYCCHELFGFDIMLDENLKPWVLEVNISPSLHSNSPLDISIKGQMIRDLLNLAGF 896

  Fly   790 QVPPK---LNERQQADILEELNLTGPLCHDKRIFTTCLTAEEVRKHNQYTNRSIEFREEYVDTIL 851
            .:|.|   .........:.|.:......|...|     .|||..|..:|..:.|..::.|. |:|
 Frog   897 VLPSKDEVCTASPSGSSISESSAGKDKGHSLEI-----VAEEKMKRARYLIQKIPDKDLYA-TVL 955

  Fly   852 DNLLPDDVRCLIVAEDELARCQPLERIFPTAGTHVYLRYVENARYYNRLLDAWETKYAKNREMGI 916
            |:|.|:|||.|:..||||:||...|||||:..|..|||:.|..||.|.|.:.||.||..:||.|.
 Frog   956 DHLTPEDVRVLVETEDELSRCGQFERIFPSPITSRYLRFFEQPRYLNILTNQWEQKYYTDRERGR 1020

  Fly   917 ALLSRYCRDKYHLQVSDAAMEKEPNVALTEIDMLHVRKDEVLDGATTLAILKPVVQEGCEVAPIP 981
            .||..:|...||   |...:..:    |........|.|..|:|.|...:::.        .|:|
 Frog  1021 DLLRSFCLKNYH---SGTVLPSQ----LFSFPRSPTRTDAHLNGFTRSEVMRH--------GPLP 1070

  Fly   982 D 982
            :
 Frog  1071 N 1071

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL4B	NP_001260010.1	TTL	504..799	CDD:281171	151/297 (51%)
ttll4	XP_002933990.3	TTL	612..905	CDD:397308	151/293 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	344	1.000	Domainoid score	I1053
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	498	1.000	Inparanoid score	I1340
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250453at33208
OrthoFinder	1	1.000	-	-		FOG0006381
OrthoInspector	1	1.000	-	-		otm48456
Panther	1	1.100	-	-	O	PTHR12241
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4643
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160