DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp2 and foxj1a

DIOPT Version :9

Sequence 1:	NP_476834.1	Gene:	slp2 / 33608	FlyBaseID:	FBgn0004567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001070174.2	Gene:	foxj1a / 767737	ZFINID:	ZDB-GENE-060929-1178	Length:	458	Species:	Danio rerio

Alignment Length:	239	Identity:	74/239 - (30%)
Similarity:	101/239 - (42%)	Gaps:	58/239 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 NLNTTNWGSPEDH------EAESDPESDLDVTSMSPAPVANPNESD------------------- 138
            |.:|....||..|      :|.|.|.:....:...|.....|..:.
Zfish    65 NASTGQHTSPSSHSHLMGSDAPSSPLAGDPASIGMPLTPGKPTAASFCRVPMFSALPSLVAHGHC 129

  Fly   139 PDEVDEEFVEEDIECDGETTDGDAENKSNDGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTL 203
            |||||                    .|||.         :.||||||..||.||::.|.:.::||
Zfish   130 PDEVD--------------------YKSNP---------HIKPPYSYATLICMAMQASKKTKITL 165

  Fly   204 NGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGS 268
            :.||::|..|..|:|.....|||||||||||||||:||||..|:||||.:|.:||...:..:..:
Zfish   166 SCIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPRQKDEPGKGGFWKIDPQYAERLLNEA 230

  Fly   269 TGKLRR---RTTAASRSRLAAFKRSLIGPMFPGLAAYPQFGQFL 309
            ..|.|.   :...|.:.|| .......|.:...|:..|:..|.|
Zfish   231 YKKRRLPPVQINPALQHRL-RMNAQATGVISRNLSVSPESQQLL 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	46/84 (55%)
foxj1a	NP_001070174.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	68..99		7/30 (23%)
		Forkhead	142..228	CDD:278670	46/85 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..324
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.950