DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp2 and foxf1

DIOPT Version :9

Sequence 1:	NP_476834.1	Gene:	slp2 / 33608	FlyBaseID:	FBgn0004567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001039226.1	Gene:	foxf1 / 734087	XenbaseID:	XB-GENE-478922	Length:	373	Species:	Xenopus tropicalis

Alignment Length:	384	Identity:	111/384 - (28%)
Similarity:	152/384 - (39%)	Gaps:	107/384 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 PVANPNESDPDEV------DEEFVEEDIECDGETTDGDAENKSNDG--KPVKDKKGNEKPPYSYN 186
            |...|.:|.|...      .:..|.|...|..:|      .|:|.|  :|       |||||||.
Frog     9 PSQPPAQSSPMSAATDKHGGQPSVMESANCATKT------KKTNAGIRRP-------EKPPYSYI 60

  Fly   187 ALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKG 251
            |||:|||:.|..|||||:.||:::.:..|::|.:.|||:||:|||||||:||:|:|:....||||
Frog    61 ALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKG 125

  Fly   252 NYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFP-----GLAAYPQFGQF--- 308
            :||.:||::|.:|   ..|..|||.....|      |...:.||:.     |....|:...|
Frog   126 HYWTIDPASEFMF---EEGSFRRRPRGFRR------KCQALKPMYSMMNGLGFNHIPETYSFQGA 181

  Fly   309 ---LTYPPTA--------------PSLLASMYQRYNP---FAPKGGPGHPGLPPGLPG------- 346
               :..||.:              ||.:..|....:|   .|..||..:.|...|..|
Frog   182 SGTIACPPNSLSLDSGIGMMNGHLPSNVDGMGLSGHPVSHIAANGGHSYMGSCTGSSGGDYSHHD 246

  Fly   347 ----LPGPPGPQGP------------PGPPPP-----PF-----VAPPTSSELYQRLQYQQLLHQ 385
                |.|..|...|            |....|     |.     .|.|.||.|......|..|||
Frog   247 SGSPLLGGGGVMEPHSVYSSPASAWAPSASTPYIKQQPLSPCNSAANPLSSSLSSHSLDQSYLHQ 311

  Fly   386 --HAAAAALAAHQRQ--------------LSVAAASAASQPPPTHHHPHLAVGQAPLSP 428
              |..|:.|....|.              .|..|.:::|....:..:.|..||...:.|
Frog   312 NSHNTASELQGIPRYHSQSPSMNDRKEFVFSFNAMASSSMHSGSGSYYHQQVGYQDIKP 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	47/84 (56%)
foxf1	NP_001039226.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51		11/47 (23%)
		Forkhead	53..139	CDD:365978	49/88 (56%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..255		4/18 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	283..306		6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910