DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp2 and foxo

DIOPT Version :9

Sequence 1:NP_476834.1 Gene:slp2 / 33608 FlyBaseID:FBgn0004567 Length:451 Species:Drosophila melanogaster
Sequence 2:NP_001262557.1 Gene:foxo / 41709 FlyBaseID:FBgn0038197 Length:622 Species:Drosophila melanogaster


Alignment Length:414 Identity:103/414 - (24%)
Similarity:154/414 - (37%) Gaps:119/414 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 HNNNNLNTTNWGSPEDHEAESDPESDLDVTSMSPAPVANPNESDPDEVDEEFVEEDIECDG---- 155
            |.:|.|.....|.          :..||| ...|...|..| :.|....|.|||...|.|.    
  Fly    14 HTDNGLAMDQLGG----------DLPLDV-GFEPQTRARSN-TWPCPRPENFVEPTDELDSTKAS 66

  Fly   156 --ETTDGDAENKSNDGKPVK--DKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPY 216
              :...||::....:....|  ..:.|.....||..||..||..:::|||||:.|||:::.|.||
  Fly    67 NQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPY 131

  Fly   217 YRD-----NKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRT 276
            ::|     :..||:|||||||||:..|::|..  :..||.::|||:|.|:       .||..||.
  Fly   132 FKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQN--EGTGKSSWWMLNPEAK-------PGKSVRRR 187

  Fly   277 TAA------------SRSRLAAFKRS-LIG----------PMFPGLAAYPQF-----GQFLTYPP 313
            .|:            ::.|:.|.::: ::|          .:..||..:|:.     |.|...|.
  Fly   188 AASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPD 252

  Fly   314 --TAPSLLASMYQRYNPFAPKGGPGHPGLP-------------PGLPGLPGPPGPQ--------- 354
              ...|..||...|.:|...:......|.|             ..|..|.|....:         
  Fly   253 FRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQ 317

  Fly   355 ------GPPGPPPPPFVAPPTSSELYQRLQYQQ--------------------LLHQ-------H 386
                  |.|..||||...||...:..|:.|.|.                    |||:       |
  Fly   318 GFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMH 382

  Fly   387 AAAAALAAHQRQLSVAAASAASQP 410
            .|...|:.:....:::.|...|:|
  Fly   383 NARDGLSPNSVTTTMSPAYPNSEP 406

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp2NP_476834.1 Forkhead 180..265 CDD:306709 38/89 (43%)
foxoNP_001262557.1 FH 95..175 CDD:238016 35/81 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45445531
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2294
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.740

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