DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp2 and foxa2

DIOPT Version :9

Sequence 1:NP_476834.1 Gene:slp2 / 33608 FlyBaseID:FBgn0004567 Length:451 Species:Drosophila melanogaster
Sequence 2:NP_989423.1 Gene:foxa2 / 395063 XenbaseID:XB-GENE-480476 Length:434 Species:Xenopus tropicalis


Alignment Length:326 Identity:101/326 - (30%)
Similarity:134/326 - (41%) Gaps:74/326 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   103 TNWGSPEDHEAESDPESDLDVTSMSP-APVANPNESDPDEVDEEFVEEDIECDGETTDGDAENKS 166
            |...|...|.:.|........|||:. ||..|.|...|     .:.:.:|            |:|
 Frog    88 TGVASMASHLSPSMSPMSAQATSMNALAPYTNMNSMSP-----IYGQSNI------------NRS 135

  Fly   167 NDGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHN 231
            .|.|..:....:.||||||.:||.|||:||..|.|||:.||::||...|:||.|:|.|||||||:
 Frog   136 RDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHS 200

  Fly   232 LSLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRL--AAFKRSLIGP 294
            ||.|.||:||||..|.||||::|.|.|.:.::|..|...:.::|.....:..|  ...|:...|.
 Frog   201 LSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKKPSLREGGGKKLSEGS 265

  Fly   295 MFPGLAA----YPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQG 355
            ...|.||    ....|....:..::|    ...|:.:....|...|                   
 Frog   266 SSVGSAANSSSESSVGNESPHSSSSP----CQEQKRSLVDMKSSQG------------------- 307

  Fly   356 PPGPPPPPFVAPPTSSELYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQPPPTHH----H 416
                ..|...|.|.|       |.|.||.||        |    ||.:..|.|...|.||    |
 Frog   308 ----LSPDHAASPAS-------QAQHLLSQH--------H----SVLSHEAQSHLKPEHHYSFNH 349

  Fly   417 P 417
            |
 Frog   350 P 350

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp2NP_476834.1 Forkhead 180..265 CDD:306709 50/84 (60%)
foxa2NP_989423.1 Forkhead_N 17..148 CDD:369872 17/76 (22%)
FH 149..237 CDD:214627 51/87 (59%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..339 26/135 (19%)
HNF_C 349..423 CDD:370449 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.910

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