DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp2 and foxi3a

DIOPT Version :9

Sequence 1:	NP_476834.1	Gene:	slp2 / 33608	FlyBaseID:	FBgn0004567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_944599.2	Gene:	foxi3a / 387257	ZFINID:	ZDB-GENE-031126-3	Length:	353	Species:	Danio rerio

Alignment Length:	250	Identity:	86/250 - (34%)
Similarity:	111/250 - (44%)	Gaps:	64/250 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 KPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRH 244
            :|||||:|||.|||..:..:||||:.||:|:..|.|:|..:|..||||||||||||.||:||||.
Zfish   116 RPPYSYSALIAMAIHGAPNRRLTLSQIYQYVADNFPFYNKSKASWQNSIRHNLSLNDCFMKVPRD 180

  Fly   245 YDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTT-----------AASRSRLAAFKRSLIGPMFPG 298
            ..||||||||.|||:.|.:|..|:..:.|:|.:           :.|.|.|::       |..|.
Zfish   181 DSDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDSLAEEEGKGYSGSDSALSS-------PKNPS 238

  Fly   299 LAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGP--------PGPQG 355
            .::  :.|........||.|        |.|..:.|....|....|  ||.|        ..|.|
Zfish   239 DSS--ERGNSPISTDQAPCL--------NSFLNQMGDVASGSREAL--LPSPLAVPLSQRSSPTG 291

  Fly   356 PPGPPPPPFVAP--------------------------PTSSELYQRLQYQQLLH 384
            ..|...|....|                          |.||:||..|....||:
Zfish   292 VYGSYSPNATMPQWETQIPQSSISSTPYKDGYSDSMLNPYSSQLYPVLGSSDLLY 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	52/84 (62%)
foxi3a	NP_944599.2	FH	116..204	CDD:214627	53/87 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820