Protein Alignment slp2 and FOXD4L4

DIOPT Version :9

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_954714.2
• Gene: FOXD4L4 / 349334
• HGNCID: 23762
• Length: 416
• Species: Homo sapiens
• Alignment Length: 411
• Identity: 130/411 - (31%)
• Similarity: 164/411 - (39%)
• Gaps: 111/411 - (27%)

  Fly    44 LNLTNLMKMARTPH--LKSSFSINSILPETVEHHDEDEEEDVEKKSPAKFPPNHNNNNLNTTNWG 106
            :||....:...||.  |:.|...:..:....|..||||.||.|:::..:|........|....||
Human     1 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEARQQFLEQSLQPGLQVARWG 65

  Fly   107 S---PEDH-EAESDPESDLDVTSMSPAPVANPNESDPDEVDEEFVEEDIECDGETTDGDAENKSN 167
            .   |.:| |....|                   |||.|...:|                .....
Human    66 GVALPREHIEGGGGP-------------------SDPSEFGTKF----------------RAPPR 95

  Fly   168 DGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNL 232
            .....:|.:...||||||.|||.|||.|:..|||||:||..:|....||||.....|||||||||
Human    96 SAAASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNL 160

  Fly   233 SLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFP 297
            |||.||||:||....|||||||.|||:::|:|..||..:.|:|           |||..:.|
Human   161 SLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKR-----------FKRHQLTP--- 211

  Fly   298 GLAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQGPPGPPPP 362
                    |..|.:|...|:..|::   :||        |||   .|.|.|.||    .|.|...
Human   212 --------GAHLPHPFPLPAAHAAL---HNP--------HPG---PLLGAPAPP----QPVPGAY 250

  Fly   363 PFVAPPTSSELYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQPPPTHHHPHLAVGQAPLS 427
            |..||       .|..| .|||.|..        |.|.::|...|..|..              :
Human   251 PNTAP-------GRRPY-ALLHPHPL--------RYLLLSARVYAGAPKK--------------A 285

  Fly   428 PGGDSPGPSPQPLHKPVTVVS 448
            .|.|...|:|.|...|..|:|
Human   286 EGADLATPAPFPCCSPHLVLS 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	54/84 (64%)
FOXD4L4	NP_954714.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55		15/53 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	70..105		10/69 (14%)
		Forkhead	108..194	CDD:278670	55/85 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820