Protein Alignment slp2 and FOXA1

DIOPT Version :9

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_004487.2
• Gene: FOXA1 / 3169
• HGNCID: 5021
• Length: 472
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 97/274 - (35%)
• Similarity: 120/274 - (43%)
• Gaps: 44/274 - (16%)

  Fly   168 DGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNL 232
            |.|..|....:.||||||.:||.|||:|:..|.|||:.||::||...||||.|:|.|||||||:|
Human   158 DAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSL 222

  Fly   233 SLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFP 297
            |.|.|||||.|..|.||||:||.|.|.:.::|..|.  .|||:.......:..|......|....
Human   223 SFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGC--YLRRQKRFKCEKQPGAGGGGGSGSGGS 285

  Fly   298 GLAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQGPPGPPPP 362
            |....|:..:    .|:..|         ||.|  ..|.|.|:......|.|.|.| ||...|
Human   286 GAKGGPESRK----DPSGAS---------NPSA--DSPLHRGVHGKTGQLEGAPAP-GPAASP-- 332

  Fly   363 PFVAPPTSSELYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQPPPTHHHPHLAVGQAPLS 427
                             |.|.|..|.|...|:   :|...|:|.|   ||....|. |:...|.|
Human   333 -----------------QTLDHSGATATGGAS---ELKTPASSTA---PPISSGPG-ALASVPAS 373

  Fly   428 PGGDSPGPSPQPLH 441
            .......|....||
Human   374 HPAHGLAPHESQLH 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	51/84 (61%)
FOXA1	NP_004487.2	Forkhead_N	17..169	CDD:369872	3/10 (30%)
		FH_FOXA1	157..268	CDD:410812	59/111 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	269..392		38/161 (24%)
		HNF_C	398..461	CDD:401339

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910