Protein Alignment slp2 and Foxd2

DIOPT Version :10

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_001386132.1
• Gene: Foxd2 / 313504
• RGDID: 1304642
• Length: 494
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 129/387 - (33%)
• Similarity: 153/387 - (39%)
• Gaps: 113/387 - (29%)

  Fly   113 AESDPESDLDVTS--------------MSPAPVANPNESDPDEVDEEFVEEDIECDGETTD---- 159
            |.|:|::|:||..              .:|..|.......|.|..|..|.||.|..|..:|
  Rat    19 ALSEPDADIDVVGGGSGGGELTARSGPRAPRDVLPHGHELPPEEAEADVAEDEEESGGCSDCEPR 83

  Fly   160 -----GDAENKSNDGKPVKDKKGNE----------------------KPPYSYNALIMMAIRQSS 197
                 |.|....:.|..|:..:|..                      ||||||.|||.|||.||.
  Rat    84 ALGPRGAAAAAGSPGPGVQAARGATGPGPGPGPGPPSGGAATRSPLVKPPYSYIALITMAILQSP 148

  Fly   198 EKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSAED 262
            :|||||:.|.|:|....||||:....||||||||||||.||||:||...:|||||||.|||.:.|
  Rat   149 KKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESAD 213

  Fly   263 VFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFP------------GLAAYPQFGQFLTYPPTA 315
            :|..||..:.|:|           |||..:.|..|            |.||....|.||
  Rat   214 MFDNGSFLRRRKR-----------FKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFL------ 261

  Fly   316 PSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQGPPGPPPPPFVAPPTSSELYQRLQYQ 380
                       :.||..|..|: |....||....|     ||||.|.|
  Rat   262 -----------SGFAAYGAYGY-GYGLALPAYGAP-----PPGPAPHP----------------- 292

  Fly   381 QLLHQHAAAAALAAHQR-QLSVAAASAASQPP-PTHHHPHLAVGQAPLSPGGDSPGPSPQPL 440
               |.|..|.|.||... ||||....||:.|| |.......:...||........||||..|
  Rat   293 ---HPHPHAFAFAATAPCQLSVPPGRAAAPPPGPPTASVFASATSAPAPAPAPGSGPSPAGL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	FH_FOXG	180..258	CDD:410795	52/77 (68%)
Foxd2	NP_001386132.1	FH_FOXD1_D2-like	131..229	CDD:410820	61/108 (56%)