DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slp2 and Foxk1

DIOPT Version :9

Sequence 1:	NP_476834.1	Gene:	slp2 / 33608	FlyBaseID:	FBgn0004567	Length:	451	Species:	Drosophila melanogaster
Sequence 2:	NP_001032296.2	Gene:	Foxk1 / 304298	RGDID:	1309643	Length:	719	Species:	Rattus norvegicus

Alignment Length:	360	Identity:	110/360 - (30%)
Similarity:	165/360 - (45%)	Gaps:	55/360 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 PESDL-DVTSMSPAP---VANPNE--SDP---DEVDEEFVE---EDIECDGETTDGDAENKSNDG 169
            ||.|| .:.|..|:|   ::.||.  :.|   ......||:   .|::...|.....|..:..|.
  Rat   216 PEPDLRSLVSPIPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQQADT 280

  Fly   170 KPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSL 234
            ......|...||||||..||:.||..:.:::|||:|||.:|..::||||...:||||||||||||
  Rat   281 SGGDSPKDESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSL 345

  Fly   235 NKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLA--AFKRSLIGPMFP 297
            |:.|:||||..::||||::|.:||::|...:..:..|.|:|..:..|:...  :.:.:...|..|
  Rat   346 NRYFIKVPRSQEEPGKGSFWRIDPASEAKLVEQAFRKRRQRGVSCFRTPFGPLSSRSAPASPTHP 410

  Fly   298 GLAA-----------YPQFGQFLTYPPTAPSLLASMYQ-RYNPFAPKGGPGHPGLPPGLPGLPGP 350
            ||.:           ..:.|..:.:.|...|.|||:.: ||:..|| |.|  ....|.:..:|
  Rat   411 GLMSPRSSGLQTPECLSREGSPIPHDPDLGSKLASVPEYRYSQSAP-GSP--VSAQPVIMAVP-- 470

  Fly   351 PGPQGPPGPPPPPFVAPPTSSELYQRLQYQQ----LLH--QHAAAAALAAHQRQLSVAAASA--- 406
                    |.|...||.|.:......:..||    .:|  |.|....:.   |.::.:|.||
  Rat   471 --------PRPSNLVAKPVAYMPASIVTSQQPSGHAIHVVQQAPTVTMV---RVVTTSANSANGY 524

  Fly   407 --ASQPPPTHHHPHLAVGQAPLSPGGDSPGPSPQP 439
              |||......|.  ..|.|.|..|.::.|...:|
  Rat   525 ILASQGSTATSHD--TAGTAVLDLGNEARGLEEKP 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	47/84 (56%)
Foxk1	NP_001032296.2	FHA	<88..190	CDD:224630
		FHA	96..189	CDD:238017
		Forkhead	291..377	CDD:278670	47/85 (55%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820