Protein Alignment slp2 and FOXB1

DIOPT Version :9

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_036314.2
• Gene: FOXB1 / 27023
• HGNCID: 3799
• Length: 325
• Species: Homo sapiens
• Alignment Length: 299
• Identity: 92/299 - (30%)
• Similarity: 116/299 - (38%)
• Gaps: 100/299 - (33%)

  Fly   170 KPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSL 234
            :|.::...::||||||.:|..|||:.|.||.|.|:.||::||...||||:|.|.||||:|||||.
Human     3 RPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSF 67

  Fly   235 NKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGS------------------------------T 269
            |.||:|:||..|.||||::|.|.||..|:|..||                              .
Human    68 NDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQ 132

  Fly   270 GKLRRRTTAASRSRL----------------AAFKRSL-----------------IGPMFPGLAA 301
            .|||....|||.:.|                :.||...                 ...|.|..||
Human   133 AKLRLSALAASGTHLPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPVPAA 197

  Fly   302 YPQFGQFLT--------YP-----------PTAPSLLASMYQRY----NPFAPKGGPGHPGLP-- 341
            ||...|..|        :|           .|..|:.:..|..|    .|.....|...|.:|
Human   198 YPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMASGDYSAYGVPLKPLCHAAGQTLPAIPVP 262

  Fly   342 --------PGLPGLPGPPGPQGPPGPPPPPFVAPPTSSE 372
                    |.||.||.|........||.    ..||||:
Human   263 IKPTPAAVPALPALPAPIPTLLSNSPPS----LSPTSSQ 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	50/84 (60%)
FOXB1	NP_036314.2	FH_FOXB2	1..110	CDD:410817	54/106 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..325		6/18 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.940