Protein Alignment slp2 and FOXI1

DIOPT Version :10

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_036320.2
• Gene: FOXI1 / 2299
• HGNCID: 3815
• Length: 378
• Species: Homo sapiens
• Alignment Length: 286
• Identity: 98/286 - (34%)
• Similarity: 126/286 - (44%)
• Gaps: 90/286 - (31%)

  Fly   180 KPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRH 244
            :|||||:|||.|||..:.:|||||:.||:|:..|.|:|..:|.|||||||||||||.||.||||.
Human   123 RPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRD 187

  Fly   245 YDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTT--AASRSRLAAFKRSLIGPMFPGLAAYPQFGQ 307
            .|||||||||.|||:.|.:|..|:..:.|:|.:  ::|.:.||..|.....|:.......||
Human   188 EDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDSPKTTEPQ--- 249

  Fly   308 FLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGPPGPQGPPGPPPPPFVAPPTSSE 372
                     .:|                  .|..||  |....|..:    |.|||..||..:|.
Human   250 ---------DIL------------------DGASPG--GTTSSPEKR----PSPPPSGAPCLNSF 281

  Fly   373 LYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQPPPTHHHPHLAVGQAPLSPGGDSPGPSP 437
            |.....|                     |:..|      ||.|         ||.    :||.||
Human   282 LSSMTAY---------------------VSGGS------PTSH---------PLV----TPGLSP 306

  Fly   438 QPLHK------------PVTVVSRNS 451
            :|..|            |:|.:|.:|
Human   307 EPSDKTGQNSLTFNSFSPLTNLSNHS 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	FH_FOXG	180..258	CDD:410795	52/77 (68%)
FOXI1	NP_036320.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		FH_FOXI1	120..219	CDD:410827	58/95 (61%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..278		22/105 (21%)