Protein Alignment slp2 and FOXD4

DIOPT Version :9

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_997188.2
• Gene: FOXD4 / 2298
• HGNCID: 3805
• Length: 439
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 125/412 - (30%)
• Similarity: 158/412 - (38%)
• Gaps: 117/412 - (28%)

  Fly    44 LNLTNLMKMARTPH--LKSSFSINSILPETVEHHDEDEEEDVEKKSPAKFPPNHNNNNLNTTNWG 106
            :||....::..||.  |:.|...:..:....|..||||||...:    :|........|....||
Human     1 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEEEAASQ----QFLEQSLQPGLQVARWG 61

  Fly   107 S---PEDH-EAESDPESDLDVTSMSPAPVANPNESDPDEVDEEFVEEDIECDGETTDGDAENKSN 167
            .   |.:| |....|                   |||.|...||                .....
Human    62 GVALPREHIEGGGGP-------------------SDPSEFGTEF----------------RAPPR 91

  Fly   168 DGKPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNL 232
            .....:|.:...|||.||.|||.|||.||..|||||:||..:|....||||.....|||||||||
Human    92 SAAASEDARQPAKPPSSYIALITMAILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNL 156

  Fly   233 SLNKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFP 297
            |||.||||:||....|||||||.|||:::|:|..||..:.|:|           |:|.
Human   157 SLNDCFVKIPREPGRPGKGNYWSLDPASQDMFDNGSFLRRRKR-----------FQRH------- 203

  Fly   298 GLAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPGHPGLPPGLPGLPGP-PGPQGPPGPPP 361
                .|..|..|.:|...|:..|::   :||        .||...|.|..|.| ||.....||..
Human   204 ----QPTPGAHLPHPFPLPAAHAAL---HNP--------RPGPLLGAPAPPQPVPGAYPNTGPGR 253

  Fly   362 PPFVAPPTSSELYQRLQYQQLLHQHAAAAALAAHQRQLSVAAASAASQPPPTHHHPHLAVGQAPL 426
            .|:.                |||.|.        .|.|.::|.:.|..|..
Human   254 RPYA----------------LLHPHP--------PRYLLLSAPAYAGAPKK-------------- 280

  Fly   427 SPGGDSPGPSPQPLHKPVTVVS 448
            :.|.|...|:|.|...|..|:|
Human   281 AEGADLATPAPFPCCSPHLVLS 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	54/84 (64%)
FOXD4	NP_997188.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46		13/48 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..104		11/76 (14%)
		Forkhead	104..189	CDD:306709	54/84 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..232		10/50 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850