DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp2 and Foxc2

DIOPT Version :10

Sequence 1:NP_476834.1 Gene:slp2 / 33608 FlyBaseID:FBgn0004567 Length:451 Species:Drosophila melanogaster
Sequence 2:NP_001095150.1 Gene:Foxc2 / 171356 RGDID:621703 Length:494 Species:Rattus norvegicus


Alignment Length:354 Identity:116/354 - (32%)
Similarity:148/354 - (41%) Gaps:99/354 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   180 KPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSLNKCFVKVPRH 244
            ||||||.|||.|||:.:.||::||||||::||...|:||:||||||||||||||||:|||||||.
  Rat    71 KPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRD 135

  Fly   245 YDDPGKGNYWMLDPSAEDVFIGGSTGKLRRR-------TTAASRSRL-----AAFKRSLIG-PMF 296
            ...||||:||.|||.:.::|..||..:.|||       .....|:.|     |:.|.:..| |:.
  Rat   136 DKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVPKDKEERAHLKEPPPASAKGAPTGTPVA 200

  Fly   297 PG------------LAAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPG------HPGLPPG 343
            .|            .||.|...........:|........|.:...|.|.|.      |...|.|
  Rat   201 DGPKEAEKKVVVKSEAASPALPVITKVETLSPEGALQASPRSSASTPAGSPDGSLPEHHAAAPNG 265

  Fly   344 LPGL---------PGPPGPQGPPGPP------PP---PFVAPPTSSELYQRLQYQQLLHQHAAAA 390
            |||.         ..|||....|...      ||   |:.|.|.::       |.|...|...||
  Rat   266 LPGFSVETIMTLRTSPPGGDLSPAAARAGLVVPPLALPYAAAPPAA-------YAQPCAQGLEAA 323

  Fly   391 ALAAHQRQL-SVAAASAASQP-----PPT---------------------------------HHH 416
            ..|.:|..: :::..:.|.:|     ||.                                 |||
  Rat   324 GSAGYQCSMRAMSLYTGAERPAHVCVPPALDEALSDHPSGPGSPLGALNLAAGQEGALGASGHHH 388

  Fly   417 PHLAVGQAPLSPGGDSPGPSPQPLHKPVT 445
            .|    .:.|.|....|.|.|.|..:|.|
  Rat   389 QH----HSHLHPQAPPPAPQPPPAPQPAT 413

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp2NP_476834.1 FH_FOXG 180..258 CDD:410795 55/77 (71%)
Foxc2NP_001095150.1 FH_FOXC1 66..158 CDD:410818 58/86 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 166..213 8/46 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 233..267 7/33 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 380..422 12/38 (32%)

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