Protein Alignment slp2 and Foxb2

DIOPT Version :10

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_032049.1
• Gene: Foxb2 / 14240
• MGIID: 1347468
• Length: 428
• Species: Mus musculus
• Alignment Length: 286
• Identity: 103/286 - (36%)
• Similarity: 125/286 - (43%)
• Gaps: 88/286 - (30%)

  Fly   170 KPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSL 234
            :|.|....::||||||.:|..|||:.|:||.|.|:.||::||...||||::.|.||||:|||||.
Mouse     3 RPGKSSYSDQKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSF 67

  Fly   235 NKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFPGL 299
            |.||:|:||..|.||||::|.|.|...|:|..||.  ||||            ||      |..|
Mouse    68 NDCFIKIPRRPDQPGKGSFWALHPDCGDMFENGSF--LRRR------------KR------FKVL 112

  Fly   300 AAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPG---HPGLP-------------------- 341
            .|..                |.::...:..||..|||   ||..|
Mouse   113 RADH----------------AHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHH 161

  Fly   342 -PGLPGLPGPPGP--------QGPPGPPPPPFVAPPTSSELYQRLQYQQLLH----QHAAAAALA 393
             |..|  |.||.|        |..|.|.||...:.|......|. |..|..|    |.|||.|.|
Mouse   162 HPPQP--PPPPPPHMVPYFHQQPAPAPQPPHLPSQPAQQPQPQS-QPPQTSHPGKMQEAAAVAAA 223

  Fly   394 AHQRQLSVAAASAA-------SQPPP 412
            |      .|||:||       ||.||
Mouse   224 A------AAAAAAAVGSVGRLSQFPP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	FH_FOXG	180..258	CDD:410795	46/77 (60%)
Foxb2	NP_032049.1	FH_FOXB2	1..110	CDD:410817	59/126 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..217		25/101 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	408..428