DRSC/TRiP Functional Genomics Resources

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Protein Alignment slp2 and Foxb2

DIOPT Version :9

Sequence 1:NP_476834.1 Gene:slp2 / 33608 FlyBaseID:FBgn0004567 Length:451 Species:Drosophila melanogaster
Sequence 2:NP_032049.1 Gene:Foxb2 / 14240 MGIID:1347468 Length:428 Species:Mus musculus


Alignment Length:286 Identity:103/286 - (36%)
Similarity:125/286 - (43%) Gaps:88/286 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   170 KPVKDKKGNEKPPYSYNALIMMAIRQSSEKRLTLNGIYEYIMTNHPYYRDNKQGWQNSIRHNLSL 234
            :|.|....::||||||.:|..|||:.|:||.|.|:.||::||...||||::.|.||||:|||||.
Mouse     3 RPGKSSYSDQKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSF 67

  Fly   235 NKCFVKVPRHYDDPGKGNYWMLDPSAEDVFIGGSTGKLRRRTTAASRSRLAAFKRSLIGPMFPGL 299
            |.||:|:||..|.||||::|.|.|...|:|..||.  ||||            ||      |..|
Mouse    68 NDCFIKIPRRPDQPGKGSFWALHPDCGDMFENGSF--LRRR------------KR------FKVL 112

  Fly   300 AAYPQFGQFLTYPPTAPSLLASMYQRYNPFAPKGGPG---HPGLP-------------------- 341
            .|..                |.::...:..||..|||   ||..|                    
Mouse   113 RADH----------------AHLHSGSSKGAPGTGPGGHLHPHHPHHAHHHHHHHHHAAHHHHHH 161

  Fly   342 -PGLPGLPGPPGP--------QGPPGPPPPPFVAPPTSSELYQRLQYQQLLH----QHAAAAALA 393
             |..|  |.||.|        |..|.|.||...:.|......|. |..|..|    |.|||.|.|
Mouse   162 HPPQP--PPPPPPHMVPYFHQQPAPAPQPPHLPSQPAQQPQPQS-QPPQTSHPGKMQEAAAVAAA 223

  Fly   394 AHQRQLSVAAASAA-------SQPPP 412
            |      .|||:||       ||.||
Mouse   224 A------AAAAAAAVGSVGRLSQFPP 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
slp2NP_476834.1 Forkhead 180..265 CDD:306709 48/84 (57%)
Foxb2NP_032049.1 FH 13..101 CDD:214627 49/87 (56%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 118..217 25/101 (25%)
E_Pc_C <342..>406 CDD:284226
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 408..428
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000010
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2114
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.940

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