Protein Alignment slp2 and Foxm1

DIOPT Version :9

• Sequence 1: NP_476834.1
• Gene: slp2 / 33608
• FlyBaseID: FBgn0004567
• Length: 451
• Species: Drosophila melanogaster
• Sequence 2: NP_032047.4
• Gene: Foxm1 / 14235
• MGIID: 1347487
• Length: 757
• Species: Mus musculus
• Alignment Length: 555
• Identity: 131/555 - (23%)
• Similarity: 191/555 - (34%)
• Gaps: 176/555 - (31%)

  Fly    26 PLP------PTTHHSALQSP---------------------HPVGLNLTNLMKMARTPH-----L 58
            |||      .|:...|.:||                     .|.|:.:.|   ...||:     :
Mouse    17 PLPVQNAPSETSEEEAKRSPAQPEPAPAQASQEVAESSSCKFPAGIKIIN---HPTTPNTQVVAI 78

  Fly    59 KSSFSINSILPETVEHHDEDEEEDVEKKSPAKF-------PPNHNNNNLNTTNWGSPEDHEAESD 116
            .|:..|.||:........|.     ....|.:|       |.:|.:         .|:.|.:...
Mouse    79 PSNADIQSIITALTAKGKES-----GSSGPNRFILISSGGPSSHPS---------QPQAHSSRDS 129

  Fly   117 PESDLDVTSMSP------APVANPNESDPDEVDEEFVEEDIECDGETTDGDAEN------KSNDG 169
            ..:::...::.|      .||..|..:.|.:..|.:...  |..|.|.|....|      .|:||
Mouse   130 KRAEVITETLGPKPAAKGVPVPKPPGAPPRQRQESYAGG--EAAGCTLDNSLTNIQWLGKMSSDG 192

  Fly   170 ------KPVKDKKGN-------------------------EKPPYSYNALIMMAIRQSSEKRLTL 203
                  |...::|.|                         |:|||||.|:|..||..:..||:||
Mouse   193 LGPCSVKQELEEKENCHLEQNRVKVEEPSGVSTSWQDSVSERPPYSYMAMIQFAINSTERKRMTL 257

  Fly   204 NGIYEYIMTNHPYYRD-NKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSA------E 261
            ..||.:|..:.||::. .|.||:|||||||||:..||   |.....||.::|.:.|||      :
Mouse   258 KDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFV---RETSANGKVSFWTIHPSANRYLTLD 319

  Fly   262 DVFIGGSTG-----------------KLRRRTTAASRSRLAAFKRSLIGPMFPGLAAY------P 303
            .||.....|                 :|.|..|..:...|.|  |..:.|:.|.:::|      |
Mouse   320 QVFKPLEPGSPQSPEHLESQQKRPNPELHRNVTIKTEIPLGA--RRKMKPLLPRVSSYLVPIQFP 382

  Fly   304 QFGQFLTYP------PTAPSLLASMYQRYNP---FAPKGGPGHPGLPPGLPGLPGPPGPQGPPGP 359
            .....:..|      |.|.||::|...|::.   .|||......|:.|             .|..
Mouse   383 VNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVLLSSEGIAP-------------LPAT 434

  Fly   360 PPPPFVAPPTSSE-LYQRLQYQQLLHQHAAAAALAAH-QRQLSVAAASAASQPPPTHHHPH-LAV 421
            .||....|....| |...|..|.:..:........|| :|.:.|       :.||....|. .|.
Mouse   435 EPPKEEKPLLGGEGLLPLLPIQSIKEEEMQPEEDIAHLERPIKV-------ESPPLEEWPSPCAS 492

  Fly   422 GQAPLSPGGD--SPGPSPQP------LHKPVTVVS 448
            .:..||...:  |..|:|:|      |..|...||
Mouse   493 LKEELSNSWEDSSCSPTPKPKKSYCGLKSPTRCVS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slp2	NP_476834.1	Forkhead	180..265	CDD:306709	40/91 (44%)
Foxm1	NP_032047.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..54		7/36 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..167		13/85 (15%)
		FH	234..309	CDD:238016	36/77 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	323..348		1/24 (4%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	500..560		8/28 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..635
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	660..709

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820